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Author's reply to the Letter "The emergence of zoonotic rat hepatitis E virus infection".
Hepatology : Official Journal of the American Association for the Study of Liver Diseases 2020 March 20
We thank Dr. C. Adlhoch and Dr. SA Baylis for their comments on our study describing the impact of rat hepatitis E virus (Orthohepevirus C genotype 1 or HEV-C1) on human health in Hong Kong. We concur with them that HEV-C1 infection is currently a blind spot in hepatitis E diagnostic testing. As they point out, routinely used molecular assays for HEV diagnostics or blood donor screening would not be able to detect HEV-C1.
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