Clinical and Economic Impact of Implementing OVIVA Criteria on Patients With Bone and Joint Infections in Outpatient Parenteral Antimicrobial Therapy.

Michael Marks, Lucy C K Bell, Imogen Jones, Tommy Rampling, Katharina Kranzer, Stephen Morris-Jones, Sarah Logan, Gabriele Pollara

Clinical Infectious Diseases 2020 June 25

The OVIVA study demonstrated noninferiority for managing bone and joint infections (BJIs) with oral antibiotics. We report that 79.7% of OPAT patients being treated for BJIs at our center would be eligible for oral antibiotics, saving a median (IQR) 19.5 IV-antibiotic days (8.5-37) and GBP 1234 (569-2594) per patient.

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