Clinical effects of the adjunctive use of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in the management of peri-implant diseases: a randomized clinical trial.

AIM: To evaluate the efficacy of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth-rinse, as an adjunct to professionally and patient-administered mechanical plaque removal, in the treatment of peri-implant mucositis (PiM).

MATERIAL AND METHODS: Patients displaying PiM in, at least, one implant were included in this randomized, double-blinded, clinical trial. Subjects received professional prophylaxis (baseline and 6-months) and were instructed to regular oral hygiene practices and to rinse, twice daily, with the test or placebo mouth-rinses, during one year. Clinical, radiographic and microbiological outcomes were evaluated at baseline, 6 and 12 months. Disease resolution was defined as absence of bleeding on probing (BOP). Data was analysed by repeated measures ANOVA, Student-t and chi square tests.

RESULTS: Fifty-four patients were included and 46 attended the final visit (22 in control and 24 in test group). In the test group, there was a 24.49% greater reduction in BOP at the buccal sites (95% confidence interval [3.65-45.34%]; p=0.002) than in controls. 58.3% of test implants and 50% controls showed healthy peri-implant tissues at final visit (p>0.05).

CONCLUSIONS: The use of the test mouth-rinse demonstrated some adjunctive benefits in the treatment of PiM. Complete disease resolution could not be achieved in every case. This article is protected by copyright. All rights reserved.