Yuan Li, Xinyu Wu, Min Liu, Ke Deng, Annamaria Tullini, Xiao Zhang, Junyu Shi, Hongchang Lai, Maurizio S Tonetti
AIM: Treatment of periodontitis, a chronic inflammatory disease driven by biofilm dysbiosis, remains challenging due to patients' poor performance and adherence to the necessary oral hygiene procedures. Novel, artificial intelligence-enabled multimodal-sensing toothbrushes (AI-MST) can guide patients' oral hygiene practices in real-time and transmit valuable data to clinicians, thus enabling effective remote monitoring and guidance. The aim of this trial was to assess the effect of such a system as an adjunct to clinical practice guideline-conform treatment...
April 17, 2024: Journal of Clinical Periodontology
Young-Chang Ko, Jungwon Lee, Istvan Urban, Yang-Jo Seol, Yong-Moo Lee, Ki-Tae Koo
AIM: This study investigated the adjunctive effect of polydeoxyribonucleotide (PDRN) on bone formation in alveolar ridge preservation (ARP) sockets. MATERIALS AND METHODS: Both mandibular second, third and fourth premolars of eight beagle dogs were randomly divided into ARP and ARP/PDRN groups. Following tooth extraction, ARP procedures were conducted using collagenized alloplastic graft material and bilayer collagen membrane soaked with normal saline (ARP group) or PDRN (ARP/PDRN group) for 10 min before application...
April 13, 2024: Journal of Clinical Periodontology
(no author information available yet)
No abstract text is available yet for this article.
April 3, 2024: Journal of Clinical Periodontology
(no author information available yet)
No abstract text is available yet for this article.
April 3, 2024: Journal of Clinical Periodontology
J Li, L J Ye, Y W Dai, H W Wang, J Gao, Y H Shen, F Wang, Q G Dai, Y Q Wu
AIM: This study aimed to reveal the unique microenvironment of peri-implantitis through single-cell analysis. MATERIALS AND METHODS: Herein, we performed single-cell RNA sequencing (scRNA-seq) of biopsies from patients with peri-implantitis (PI) and compared the results with healthy individuals (H) and patients with periodontitis (PD). RESULTS: Decreased numbers of stromal cells and increased immune cells were found in the PI group, which implies a severe inflammatory infiltration...
April 2, 2024: Journal of Clinical Periodontology
Maria Elisa Galarraga-Vinueza, Shayan Barootchi, Leonardo Mancini, Hamoun Sabri, Frank Schwarz, German O Gallucci, Lorenzo Tavelli
AIM: To apply high-frequency ultrasound (HFUS) echo intensity for characterizing peri-implant tissues at healthy and diseased sites and to investigate the possible ultrasonographic markers of health versus disease. MATERIALS AND METHODS: Sixty patients presenting 60 implants diagnosed as healthy (N = 30) and peri-implantitis (N = 30) were assessed with HFUS. HFUS scans were imported into a software where first-order greyscale outcomes [i...
April 1, 2024: Journal of Clinical Periodontology
Yihua Yue, Kathleen M Hovey, Michael J LaMonte, Jean Wactawski-Wende, Chris A Andrews, Amy E Millen
AIM: To examine the association of dietary patterns with periodontal disease (PD) and its progression over 5 years. MATERIALS AND METHODS: Analyses involved 1197 post-menopausal women from the OsteoPerio cohort. Dietary patterns assessed include Healthy Eating Index-2015 (HEI), Alternative HEI (AHEI), Dietary Approaches to Stop Hypertension (DASH) and alternate Mediterranean Diet (aMed) at baseline (the average of two food frequency questionnaires administered between 1993 and 2001)...
March 27, 2024: Journal of Clinical Periodontology
Valentin Bartha, Dan Grünfeld, Aleksandra Kopunic, Christian Klein, Diana Wolff, Petra Ratka-Krüger, Johan Peter Woelber, Christian Meller
AIM: To evaluate the suitability of a Doppler ultrasound probe in detecting the greater palatine artery or its greater branches non-invasively. MATERIALS AND METHODS: The palatal mucosa of 108 participants (median age 34 years, 51 female) was systematically divided into transversal sectors, each aligning with the positions of the upper molars (M), premolars (P) and canine teeth (C), aiming to facilitate precise and consistent localization of the detected palatal blood vessel across different patients...
March 20, 2024: Journal of Clinical Periodontology
Lenz Surdiacourt, Véronique Christiaens, Thomas De Bruyckere, Stefanie De Buyser, Aryan Eghbali, Stijn Vervaeke, Faris Younes, Jan Cosyn
AIM: To compare connective tissue graft (CTG) with collagen matrix (CMX) in terms of increase in buccal soft tissue profile (BSP) when applied at single implant sites. MATERIALS AND METHODS: Patients with a single tooth gap in the anterior maxilla and horizontal mucosa defect were enrolled in a multi-centre randomized controlled trial. All were fully healed sites with a bucco-palatal bone dimension of at least 6 mm, and received an immediately restored single implant using a full digital workflow...
March 14, 2024: Journal of Clinical Periodontology
Hyun-Chang Lim, Kwang-Seok Lee, Seung-Yun Shin, Ronald E Jung, Ui-Won Jung, Daniel S Thoma
AIM: To determine the effects of implant timing and type of soft-tissue grafting on histological and histomorphometric outcomes in a preclinical model. MATERIALS AND METHODS: Four implant placement protocols were randomly applied at the mesial root sites of the third and fourth mandibular premolars in 10 mongrel dogs: immediate placement (group IP), early placement (group EP), delayed placement with/without alveolar ridge preservation (groups ARP and DP, respectively)...
March 14, 2024: Journal of Clinical Periodontology
Andrew Liaw, Chun Liu, Mark Bartold, Sašo Ivanovski, Pingping Han
AIM: To evaluate the effect of non-surgical periodontal therapy (NSPT) on salivary histone deacetylases (HDACs) gene expression in patients with Stage III-IV periodontitis at baseline and at 3 and 6 months post NSPT treatment. MATERIALS AND METHODS: Twenty patients completed the study. Periodontitis (as well as the corresponding staging and grading) was diagnosed according to the 2017 World Workshop Classification. Clinical measures were recorded and whole unstimulated saliva was collected at baseline and at 3 and 6 months after NSPT...
March 11, 2024: Journal of Clinical Periodontology
Sam Asher, Anna Liisa Suominen, Ruth Stephen, Tiia Ngandu, Seppo Koskinen, Alina Solomon
AIM: Emerging evidence suggests association of tooth loss with impaired cognition. However, the differential effects of anterior versus posterior tooth loss, occlusal support loss and chewing ability are not considered comprehensively. MATERIALS AND METHODS: We conducted cross-sectional (N = 4036) and longitudinal analyses (N = 2787) on data from Health 2000 and 2011 Surveys for associations of posterior occlusal support loss, anterior versus posterior tooth loss, and chewing ability with baseline cognition and 11-year cognitive decline...
March 11, 2024: Journal of Clinical Periodontology
Wenchuan Liu, Aimei Song, Yixi Wu, Pizhang Gong, Jingjing Zhao, Liguo Zhang, Xinyang Liu, Ruwei Wang, Hongmei Guo, Pishan Yang
AIM: To evaluate the effect of subgingival delivery of progranulin (PGRN)/gelatin methacryloyl (GelMA) complex as an adjunct to scaling and root planing (SRP) on an experimental periodontitis dog model with Class II furcation involvement (FI). MATERIALS AND METHODS: A Class II FI model was established, and the defects were divided into four treatment groups: (a) no treatment (control); (b) SRP; (c) SRP + GelMA; (d) SRP + PGRN/GelMA. Eight weeks after treatment, periodontal parameters were recorded, gingival crevicular fluid and gingival tissue were collected for ELISA and RT-qPCR, respectively, and mandibular tissue blocks were collected for micro computed tomography (micro-CT) scanning and hematoxylin and eosin (H&E) staining...
March 10, 2024: Journal of Clinical Periodontology
Vincent J J Donker, Gerry M Raghoebar, Kirsten W Slagter, Diederik F M Hentenaar, Arjan Vissink, Henny J A Meijer
AIM: To compare the marginal bone level of immediately placed implants, with either immediate or delayed provisionalization (IP or DP), in the maxillary aesthetic zone after 10 years of function. MATERIALS AND METHODS: Participants with a failing tooth in the maxillary aesthetic zone were randomly assigned to immediate implant placement with either IP (n = 20) or DP (n = 20) after primary wound closure with a free gingival graft...
March 7, 2024: Journal of Clinical Periodontology
Silas Alves-Costa, Gustavo G Nascimento, Marco A Peres, Huihua Li, Susilena Arouche Costa, Cecilia Claudia Costa Ribeiro, Fábio Renato Manzolli Leite
AIM: Investigating the association between sugar-sweetened beverages (SSBs) and periodontitis and whether the awareness of diabetes modifies this relationship. MATERIALS AND METHODS: Cross-sectional analysis was conducted using the National Health and Nutrition Examination Survey (NHANES III) data involving US adults aged 30-50. Periodontitis was classified according to the Centers for Disease Control and Prevention and American Academy of Periodontology (CDC-AAP), and SSB consumption as dichotomous (<5 or ≥5, <7 or ≥7 and <14 or ≥14 times/week), ordinal and continuous variables...
March 7, 2024: Journal of Clinical Periodontology
Koji Mizutani, Isao Minami, Risako Mikami, Daisuke Kido, Kohei Takeda, Keita Nakagawa, Shu Takemura, Natsumi Saito, Hiromi Kominato, Eri Sakaniwa, Kuniha Konuma, Yuichi Izumi, Yoshihiro Ogawa, Takanori Iwata
AIM: This study aimed to investigate the effects of diabetes care on periodontal inflammation. MATERIALS AND METHODS: This prospective cohort study included 51 Japanese patients with type 2 diabetes who underwent intensive diabetes care including educational hospitalization and regular outpatient treatment for 6 months. Dental prophylaxis without subgingival scaling was provided three times during the observational period. Associations between changes in periodontal parameters and glycaemic control levels were evaluated using multiple regression analysis...
March 6, 2024: Journal of Clinical Periodontology
Emmanuel Wiernik, Adeline Renuy, Sofiane Kab, Philippe Gabriel Steg, Marcel Goldberg, Marie Zins, Giuseppina Caligiuri, Philippe Bouchard, Maria Clotilde Carra
AIM: To assess the prevalence of severe periodontitis based on the population-based CONSTANCES cohort using a validated self-reported questionnaire. MATERIALS AND METHODS: Individuals were selected from the adult population in France using a random sampling scheme. Analyses were restricted to those invited in 2013-2014 who completed the periodontal health questionnaire at the 2017 follow-up. The risk of severe periodontitis was assessed using the periodontal screening score (PESS) and weighting coefficients were applied to provide representative results in the general French population...
March 2, 2024: Journal of Clinical Periodontology
Elin Hadler-Olsen, Natalia Petrenya, Birgitta Jönsson, Ólöf Anna Steingrímsdóttir, Audun Stubhaug, Christopher Sivert Nielsen
AIM: To assess the relationship between periodontitis and experimental pain tolerance. MATERIALS AND METHODS: Participants from the population-based seventh survey of the Tromsø Study with data on periodontitis were included (n = 3666, 40-84 years old, 51.6% women). Pain tolerance was assessed through (i) pressure pain tolerance (PPT) test with a computerized cuff pressure algometry on the leg, and (ii) cold-pressor tolerance (CPT) test where one hand was placed in circulating 3°C water...
March 1, 2024: Journal of Clinical Periodontology
Fulong Li, Chunliang Ma, Shuang Lei, Yaping Pan, Li Lin, Chunling Pan, Qian Li, Fengxue Geng, Dongyu Min, Xiaolin Tang
AIM: Blood-brain barrier (BBB) disorder is one of the early findings in cognitive impairments. We have recently found that Porphyromonas gingivalis bacteraemia can cause cognitive impairment and increased BBB permeability. This study aimed to find out the possible key virulence factors of P. gingivalis contributing to the pathological process. MATERIALS AND METHODS: C57/BL6 mice were infected with P. gingivalis or gingipains or P. gingivalis lipopolysaccharide (P...
February 27, 2024: Journal of Clinical Periodontology
Fatemah Hasan, Antonio Magan-Fernandez, Aliye Akcalı, Chuanming Sun, Nikos Donos, Luigi Nibali
AIM: To assess periodontal stability and the association between tooth- and patient-related factors and tooth loss during supportive periodontal care (SPC). MATERIALS AND METHODS: A prospective observational study was carried out on previously treated periodontitis patients followed up for 5 years in SPC. The risk profile (low, moderate, high) of each patient based on periodontal risk assessment (PRA) scoring at baseline was evaluated, and tooth loss rates were analysed...
February 26, 2024: Journal of Clinical Periodontology
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