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Clinicians vs. epidemiologists: Patch testing with methyldibromo glutaronitrile as a controversial issue.

The preservative methyldibromo glutaronitrile (MDBGN) (CAS 35691-65-7) is known since long as an important contact allergen mainly used in cosmetics (Review: [1]). MDBGN was banned EU-wide from being used in leave-on products in 2005, for rinse-off products in 2008, and further restricted for non-cosmetic (technical) applications in 2010. However, positive reactions in patch testing (PT) continued to occur. This article is protected by copyright. All rights reserved.

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