Obstetrical complications of thin endometrium in assisted reproductive technologies: a systematic review.

PURPOSE: The aim of the systematic review is to describe the obstetrical complications associated with pregnancies in the context of a thin endometrial lining.

METHODS: Systematic review of the literature.

RESULTS: Patients who conceive in the setting of a thin endometrium have a significantly increased risk of early pregnancy loss, namely miscarriage and ectopic pregnancy. These patients also have a twofold increase in low birth weight and preterm delivery, as well as a significantly higher risk of intrauterine growth restriction and composite adverse perinatal outcomes.

CONCLUSIONS: In addition to the lower probability of conception, a thin endometrium in assisted reproductive technologies appears to be associated with both early and late pregnancy complications. These pregnancies thus warrant special attention and close follow-up from obstetricians.