CKD.QLD: PROFILE OF PATIENTS WITH CHRONIC KIDNEY DISEASE (CKD) FROM REGIONAL QUEENSLAND, AUSTRALIA: A REGISTRY REPORT.

BACKGROUND: Chronic Kidney Disease, Queensland (CKD.QLD) is a multidisciplinary, collaborative research platform for CKD in Queensland. All public renal services contribute towards the CKD Registry, including Toowoomba Hospital which is a referral hospital for Darling Downs Health (DDH) serving largely regional population in Queensland. We aim to present the profile of the CKD cohort recruited to CKD.QLD Registry from Toowoomba Hospital, the first comprehensive report on pre-dialysis population from regional Australia METHODS: Study subjects were patients in the DDH service who consented to be included in the CKD.QLD registry from June 2011 to December 2016. Those who were on renal replacement therapy (RRT) were excluded. Patients were followed until date of RRT, death, discharge or lost to follow up or a censor date of 30th June 2017.

RESULTS: Overall 1051 subjects representing 13% of CKD.QLD Registry gave consent of whom, 42.7% were ≥ 70 years. The mean age was 63.8 ± 15.1 years (median age 67 years) with male predominance (55.4%) The majority were born in Australia (86.4%). Aboriginal and Torre Strait islanders (A&TSI) constituted 9.6% of the cohort. The predominant CKD stages were 3b (28.9%) and 4 (27.7%). Hypertension and diabetes were noted in 91% and 44%, of subjects respectively. Diabetic nephropathy was the leading cause of CKD (26.7%) followed by renovascular disease (17.3%) and glomerulonephritis (14.8%). In 12% the diagnosis was uncertain. Major co-morbidities include coronary artery disease (24.7%) chronic lung disease (14.8%), cerebrovascular disease (11.6%) and peripheral vascular disease (8. 9%).Non-vascular co-morbidities include arthritis (24.6%), gout (23.6%) and gastro oesophageal reflux disease (19%). The multi-morbidity profile was differed by gender, diabetic status and age. During a follow-up period of 72 months 93 (8.8%) started RRT and 175 (16.6%) died. Of those 82% died without RRT and 18% died after RRT.

CONCLUSIONS: This CKD Registry cohort from regional Queensland consists mainly of older Caucasians with male predominance. The A&TSI patients were over represented compared to overall population. A significant proportion had cardio-vascular disease and multiple co-morbidities which differed by gender, diabetic status and age. This report provides valuable data for health services planning and delivery in regional Queensland. This article is protected by copyright. All rights reserved.