A European evaluation of cosmetic treatment of facial volume loss with Juvéderm™ Voluma™ in patients previously treated with Restylane Sub-Q™.

BACKGROUND: Juvéderm™ VOLUMA™ (Voluma) is a new injectable, long-lasting, resorbable hyaluronic acid filler. It restores facial volume, resulting in a more youthful appearance.

AIMS: To evaluate current in-market perceptions of the aesthetic result and use of Voluma.

PATIENTS/METHODS: Men and women >30 years who had received Restylane SubQ™ (Restylane) <2 years previously, now requiring re-treatment and who consented to Voluma treatment were included.

RESULTS: Eighty-four patients (mean age 51 years, 88% women) were recruited. The mean total volume of Voluma injected was 2.73 mL/patient. This included treatment to both sides of the face, specifically in the malar and chin areas or both (mean 1.36 mL each to the right and left sides of the face). Seventy-five percent of injectors found Voluma fairly/very easy to inject and 84.5% found it easy to sculpt/massage. Most patients (98%) and physicians (98%) rated the aesthetic effect of Voluma as improved. Injectors rated Voluma as better than previous Restylane use in 69.1% of patients (P < 0.001), and preference for Voluma was expressed in 61% of patients (P < 0.001). Ninety-nine percent of injectors would recommend Voluma to colleagues and patients (100%); 96.4% of patients would recommend it to friends. Treatment was well tolerated.

CONCLUSIONS: Voluma is easy to use, sculpt, and massage. Physicians and patients rated the cosmetic effects highly, and both groups reported a preference for Voluma in those patients previously treated with Restylane.