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Journal of Cosmetic Dermatology

Navin Bhatt, Sudha Agrawal, Kabindra Mehta
BACKGROUND: Facial appearance has increasing importance to individuals and women, in particular. Till date, there are no reports of the extrinsic factors influencing skin aging in Nepalese population. OBJECTIVES: To assess the risk factors and self-perception for facial aging in Nepalese population. METHODS: A cross-sectional study was conducted among 110 attendees aged 30-70 years visiting the dermatology outpatient department of B.P. Koirala Institute of Health Sciences...
February 17, 2019: Journal of Cosmetic Dermatology
Esraa Salah Ali Ismail, Aikaterini Patsatsi, Wafaa Mohammed Abd El-Maged, Essam El-Din Abd El-Aziz Nada
BACKGROUND: Despite the wide therapeutic options available for the treatment of melasma, including many active topical medications, technologies with lights and peelings, clinical control of this disorder is extremely challenging. OBJECTIVES: To evaluate the effect of microneedling with topical vitamin C in the treatment of melasma. METHODS: Thirty female patients with melasma received six sessions of microneedling with addition of topical vitamin C every two weeks...
February 15, 2019: Journal of Cosmetic Dermatology
Edwin D Lephart
Several journal reports, reviews, and commentaries over the last 20-25 years have pointed out the controversy attached to 17β-estradiol's inhibitory or stimulatory influence on hair follicle growth/cycling citing rodent (murine) and human results. While 17β-estradiol is the most potent sex steroid hormone in the body and has almost equal affinity for estrogen receptor (ER) alpha (α) and beta (β), there appears to be specific ER-mediated effects on scalp hair follicles/growth, etc. Additionally, the newly discovered G protein-coupled estrogen receptor (GPR30 or GPER) and the orphan receptor, estrogen-related receptor (ERR) gamma (γ), in skin and other tissue sites have potential impacts of how estrogens via these receptors may alter scalp hair characteristics, but this remains to be elucidated...
February 15, 2019: Journal of Cosmetic Dermatology
Ioannis E Liapakis, Angelos C Tzouganakis, Eleftherios I Paschalis, Miriam Englander, Athanasios Christopoulos, Georgia Gloustianou, Paraskevas Kontoes
Parry-Romberg syndrome is a hemifacial atrophy which can be complicated by melasma. We present two cases of Parry-Romberg syndrome, treated by fat transfer and bleaching of the skin using a modified "Kligman's formula." The atrophy, as well as the skin dyschromia, improved, and the results were stable.
February 15, 2019: Journal of Cosmetic Dermatology
Sajin Alexander, Banavasi S Girisha, Handattu Sripathi, Tonita M Noronha, Akshata C Alva
BACKGROUND AND OBJECTIVE: Keloids and hypertrophic scars (HTS) are abnormal fibrous reactions that persist for prolonged periods, rarely regress without treatment and recur after excision. Many modalities of treatment have been advocated but the success rates of these have been variable. The present study is an attempt to evaluate and compare the efficacy of combination of fractional CO2 laser (FCL) and intralesional steroid (ILS) against ILS alone in the treatment of keloids and HTS...
February 15, 2019: Journal of Cosmetic Dermatology
Michael H Gold, Julie Biron
INTRODUCTION: Skin rejuvenation procedures have become common with sophisticated technologies with reduced downtime and related risks. Recently, microneedling has been paired with radiofrequency to create Fractional Radiofrequency Microneedling (FRFM) to induce neocollagenesis. Frequently, topical products are applied immediately after the needling. This procedure is known as percutaneous collagen induction therapy (PCIT). Postoperative topical wound care is critical for prompt rapid and safe healing, with moist wound healing deemed of primary importance for fast and correct scarring process...
February 12, 2019: Journal of Cosmetic Dermatology
Fariba Iraji, Mojtaba Nasimi, Ali Asilian, Gita Faghihi, Samaneh Mozafarpoor, Hossein Hafezi
INTRODUCTION: Melasma is a prevalent annoying skin hyperpigmentation disorder that commonly involves reproductive-aged females. Variety of treatments with controversial results has been recommended. The aim of the current study was to evaluate combination therapy of tranexamic acid (TA) and vitamin C with and without glutathione with mesotherapy technique for treatment of melasma. METHODS AND MATERIALS: This is a randomized clinical trial study conducted on 30 patients referred to Dermatology Clinics...
February 8, 2019: Journal of Cosmetic Dermatology
Tâmara Gomes, Priscilla Baqueiro, Caroline Oliveira, Rafael Alves, Patrícia Lordelo
INTRODUCTION: The Ehlers-Danlos Syndrome (EDS) can presentis a reduction in fibroblast proliferation and collagen production. Microneedling a minimally invasive technique that through mechanical stimulus there is incentive to the production of collagen and elastin. OBJECTIVE: Present a case study in a patient with EDS complaining of flaccidity on large genital labia, using microneedling as a therapeutic proposal. METHODOLOGY: A 36-year-old female with EDS type III...
February 7, 2019: Journal of Cosmetic Dermatology
Seema Rani, Kabir Sardana
Nevus of ota is a dermal melanocytosis common among Asian patients, mottled, blue-gray macule that is usually located unilaterally within the distribution of the first and second branches of the trigeminal nerve and almost always responds well to treatment with Q-switched lasers (eg, ruby, alexandrite, and Nd: YAG). In spite of the plethora of science behind laser-tissue interactions, the objective evaluation of nevus of ota response to laser is not on firm footing and most studies report subjective percentile scoring improvement...
February 5, 2019: Journal of Cosmetic Dermatology
Xin Guan, Chun-Lei Zhang
PURPOSE: The current meta-analysis was conducted to better evaluate the role of adalimumab for patients with psoriasis in terms of its safety profile on the basis of eligible randomized controlled trials (RCTs). METHODS: The following electronic databases such as Cochrane, PubMed, and Embase database involving the index words were screened and identified for qualified studies updated to December 2018. Associated publications and sources were hand-searched for more related details...
February 4, 2019: Journal of Cosmetic Dermatology
Fatma Mohamed El-Esawy, Mohamed Saber Hussein, Amira Ibrahim Mansour
BACKGROUND: Male androgenetic alopecia (MAGA) is caused by the conversion of the terminal to vellus hair. Zinc is one of the most studied trace elements in hair disorders and biotin is one of the most prescribed supplement for its treatment. OBJECTIVES: The study aimed to evaluate serum zinc and biotin levels in MAGA patients to answer the question if there is a value to add zinc or biotin as a supplements in the MAGA treatment. PATIENTS AND METHODS: Sixty MAGA patients and 60 age, sex, and body mass index-matched healthy volunteers were included...
February 3, 2019: Journal of Cosmetic Dermatology
Georgia S K Lee
A handheld 2 MHz ultrasound Doppler device determines the presence or absence of pulsatile arterial flow immediately beneath the selected site of entry for dermal filler injection. In combination with near infrared technology to map out superficial veins, mishaps from intravascular injections may be reduced. A total of 448 patients aged range between 21 and 74 years, with 168 out of total of 1019 treatment sites having both infrared and ultrasound Doppler assisted preinjection mapping were reviewed. The injection technique is described...
January 31, 2019: Journal of Cosmetic Dermatology
Jana Pavlačková, Pavlína Egner, Jana Polašková, Jarmila Hojerová, Lucie Pinďáková, Pavel Mokrejš, Vendula Varaďová
BACKGROUND: Cosmetic products mean any substance or mixture intended to be placed in contact with the external parts of the human body (eg, epidermis, lips) and should not pass to the lower parts and penetrate to the skin. As a part of evaluation of cosmetic safety, the transdermal absorption of substances should be investigated. MATERIALS AND METHODS: In vitro absorption was investigated with Franz diffusion cells on untreated porcine skin and specimens of the same treated with 15%wt...
January 30, 2019: Journal of Cosmetic Dermatology
Liu Shuo, Yang Ting, Wu KeLun, Zhao Rui, Zhao Rui, Wang Hang
BACKGROUND: Oily skin is one of the most common dermatological complaints. Oily skin may be accompanied by enlarged pores, acne, and seborrheic dermatitis. Moreover, oily skin has negative effects on self-perception. Most therapeutic approaches used to treat oily skin have had varying degrees of efficacy and include topical treatments, such as photodynamic therapy and lasers. However, certain of these therapies for oily skin may lead to severe side effects. With the expanding use and high safety profile of botulinum toxin type A (BoNT-A), its use in the treatment of oily skin has caused significant concerns; moreover, relevant reports have gradually accumulated to address the efficacy of BoNT-A and explore its mechanisms of action...
January 29, 2019: Journal of Cosmetic Dermatology
Yaqiong Xing, Jun Xie, Si Jiang, Manandhar Upasana, Jiquan Song
INTRODUCTION: The incidence rate of psoriasis vulgaris (PSV) coexisting with Juvenile dermatomyositis (JDM) is low. Through our thorough literature search, we found that PSV arising on JDM with superficial fungal infection of facial skin is rarely reported. So, we hereby, report a case of combination of the above three diseases. Meanwhile, we also reviewed the previous literatures aiming at the related basis, clinical manifestation, diagnosis, and treatment of the diseases. Interestingly, of all cases, this case is the only one in which the symptom of muscle weakness preceded the appearance of rash...
January 29, 2019: Journal of Cosmetic Dermatology
Byungjun Ahn, Seol-Hoon Lee, Jin-Hyun Kim, Areum Goh, Sun-Gyoo Park, Cheon-Koo Lee, Nae-Gyu Kang
BACKGROUND: Due to internal or external factors, the desquamation (turnover) rate of the stratum corneum slows down, resulting in skin problems. Therefore, adjusting the exfoliation rate through cosmetics is an important issue. OBJECTIVE: This report aimed to develop exfoliating agents with lesser adverse effects and higher efficiency through an ex vivo screening method and in vivo turnover rate analysis of human skin. METHODS: Various molecules were evaluated by the ex vivo porcine skin exfoliation method and screened for their potential as effective agents...
January 29, 2019: Journal of Cosmetic Dermatology
Abhijeet Kumar Jha, Keshavamurthy Vinay, Md Zeeshan, Prasoon Kumar Roy, R K P Chaudhary, Aditi Priya
BACKGROUND: Platelet-rich plasma (PRP) is a popular procedure for the treatment of androgenetic alopecia (AGA). AIM: To ascertain the role of minoxidil 5% lotion alone versus minoxidil 5% lotion and PRP versus minoxidil 5% lotion, PRP with microneedling in AGA. MATERIAL AND METHODS: Ninety-three AGA patients with Hamilton-Norwood score 1-5 were grouped into three groups A, B, and C. Patients in group A (control group) were treated with minoxidil 5% lotion twice daily (n = 31), whereas patients in group B underwent treatment with minoxidil 5% lotion twice daily and PRP (n = 31), and group C patients received minoxidil 5% lotion twice daily, PRP, and microneedling (n = 31)...
January 28, 2019: Journal of Cosmetic Dermatology
Suparuj Lueangarun, Karuna Sriviriyakul, Therdpong Tempark, Chittima Managit, Pongtip Sithisarn
BACKGROUND: Acne vulgaris is the most common inflammatory sebaceous gland disorder in young adults. The resistant strains of Propionibacterium acnes (P. acnes) are of increasing concern in the treatment of acne. OBJECTIVES: To evaluate the efficacy of 0.5% topical mangosteen extract in nanoparticle loaded gel (containing alpha-mangostin) compared with 1% clindamycin gel for treatment of mild-to-moderate acne vulgaris. METHODS: Patients aged 18-40 years were enrolled in this double-blinded, split-face, randomized, control study...
January 27, 2019: Journal of Cosmetic Dermatology
Gabriella Fabbrocini, Alessandro Napolitano, Anna Masarà, Sara Cacciapuoti
BACKGROUND: Eyelashes have both a protective and an aesthetic function. Hypotrichosis of the eyelashes may negatively influence an individual's self-perception. OBJECTIVE: To evaluate efficacy and safety of topical administration of a new cosmetic preparation containing 15 keto fluprostenol isopropyl ester (80 µgr/mL) for the treatment of idiopathic hypotrichosis of the eyelashes. METHODS: This is a monocentric, double-blind, vehicle-controlled study...
January 21, 2019: Journal of Cosmetic Dermatology
Sidharth Sonthalia, Maya Vedamurthy, Mary Thomas, Mohamad Goldust, Abhijeet K Jha, Sakshi Srivastava, Ishad Aggarwal
BACKGROUND: Lichen Planus Pigmentosus (LPP), a disorder with stubborn treatment-refractory hyperpigmentation predominantly affects the darker skin. Deep dermal pigmentary incontinence of LPP renders the condition treatment-refractory. OBJECTIVES: Lack of a consistently effective depigmenting treatment protocol of inactive LPP mandates exploration of novel approaches. We analyzed the effect of six sessions of modified phenol peel on reduction of pigmentation of LPP in Indian patients...
January 20, 2019: Journal of Cosmetic Dermatology
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