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Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Emergence of extended-spectrum beta-lactamase and fluoroquinolone resistance genes among Irish multidrug-resistant isolates.
This study sought to identify mechanisms behind resistance to third-generation cephalosporins and ciprofloxacin in Irish multidrug-resistant Enterobacteriaceae isolates. The most prevalent extended-spectrum beta-lactamase genes identified were bla SHV-12 and bla CTX-M-15. These were associated with the fluoroquinolone resistance genes aac(6')-IB-cr, qnrA and qnrB, not previously reported in Irish isolates.
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