We have located links that may give you full text access.
Comment
Journal Article
Review
Orchestration of pathogen recognition by inflammasome diversity: Variations on a common theme.
European Journal of Immunology 2007 November
Innate immunity is a crucial part of the immune system, capable of mounting specific host responses against distinct pathogens. An integral component of the innate immune system is a network of pathogen recognition receptors, which are present at the surface of the cell or in the cytoplasm. Nucleotide oligomerization domain (Nod)-like receptors form the largest known family of intracellular innate immune sensors of microbes and danger signals that initiate early host responses. Some Nod-like receptors, such as NALP, NAIP and IPAF, form molecular machines termed inflammasomes, which are involved in the activation of inflammatory cytokines such as IL-1beta and IL-18. The diversity and the role of the different types of inflammasomes remain poorly defined. In this issue of the European Journal of Immunology, it is reported that the Gram-negative human pathogen Pseudonomas aeruginosa specifically activates an IPAF inflammasome. This finding, in combination with other recently published reports, reveals how different pathogens engage distinct types of inflammasomes, further highlighting the diversity and plasticity of inflammasomes activation.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app