Cold agglutinin induced autoimmune hemolytic anemia and NK-cell leukemia: a new association

Amy Skorupa, Uzair B Chaudhary, John Lazarchick
American Journal of Hematology 2007, 82 (7): 668-71
Cold agglutinin induced autoimmune hemolytic anemia is uncommonly associated with leukemia and lymphomas. We present a case of a young Mexican female presenting with a cold agglutinin hemolytic anemia with expression of a rare Pr antigen specificity and an aggressive NK-cell leukemia. Our patient had a rapid fatal course. To our knowledge this is the first reported case of such an association.

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