Use of voriconazole in a patient with aspergilloma caused by an itraconazole-resistant strain of Aspergillus fumigatus

E Dannaoui, D Garcia-Hermoso, J M Naccache, I Meneau, D Sanglard, C Bouges-Michel, D Valeyre, O Lortholary
Journal of Medical Microbiology 2006, 55: 1457-9
The case is reported of a patient with cavitary sarcoidosis complicated by an aspergilloma caused by an itraconazole-resistant strain of Aspergillus fumigatus, who was treated with voriconazole. The authors suggest that susceptibility testing of A. fumigatus strains is of value during long-term therapy with itraconazole, and that voriconazole may be a good option for treatment of patients infected with itraconazole-resistant strains of A. fumigatus.

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