Angiolymphoid hyperplasia with eosinophilia affecting the nail bed and underlying bone

Hiromi Tsuboi, Mikio Masuzawa, Kensei Katsuoka
Journal of Dermatology 2006, 33 (6): 399-402
A 69-year-old Japanese woman had a dark red, 1-cm nodule located in the nail bed of the middle toe of her right foot. An X-ray examination revealed an osteolytic lesion of the distal phalanx of the right middle toe. Histopathology showed a proliferation of blood vessels surrounded by epithelioid cells and an infiltration of many eosinophils and some inflammatory cells. There has been no recurrence after surgical excision of the skin lesion and the distal phalanx of the right middle toe.

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