journal
https://read.qxmd.com/read/38605482/cutaneous-adverse-events-following-covid-19-vaccination-a-case-series-of-30-japanese-patients-and-a-review-of-93-japanese-studies
#1
JOURNAL ARTICLE
Atsunori Baba, Kiyoko Yamada, Takuro Kanekura
In Japan, cutaneous adverse events (AEs) following the coronavirus disease 2019 (COVID-19) vaccination have been frequently described; however, a larger case series and literature review are lacking. There is an urgent need for an extensive investigation of new cases and previous reports to provide a thorough body of information about post-COVID-19 immunization cutaneous AEs. We aimed to analyze patients with cutaneous AEs after COVID-19 vaccination in our hospital and review previous studies of cutaneous AEs...
April 11, 2024: Journal of Dermatology
https://read.qxmd.com/read/38605475/oral-abrocitinib-in-the-treatment-of-refractory-dissecting-cellulitis-of-the-scalp-a-case-report
#2
LETTER
Sha Jin, Chao Yue, Shiwen Wang, Ping Wang
No abstract text is available yet for this article.
April 11, 2024: Journal of Dermatology
https://read.qxmd.com/read/38605474/toxic-epidermal-necrolysis-complicated-with-primary-cutaneous-aspergillosis-a-report-of-four-cases
#3
JOURNAL ARTICLE
Qianru Liu, Huilin Su, Chunli Hong, Jiande Han, Xiaohong Chen, Xuhua Tang
Primary cutaneous aspergillosis (PCA) is a rare opportunistic infection caused by Aspergillus that can be life-threatening. PCA is mainly reported in immunocompromised hosts such as patients with AIDS, those with hematologic malignancy, or infants with occlusive dressings. However, no study has previously reported PCA associated with toxic epidermal necrolysis (TEN). This study reports four cases of TEN complicated with PCA, presenting with discrete gray or black spots over newly formed epithelia. Risk factors of PCA in patients with TEN include host factors, iatrogenic factors, indoor environment, and wound care...
April 11, 2024: Journal of Dermatology
https://read.qxmd.com/read/38605467/role-of-neurogenic-inflammation-in-the-pathogenesis-of-alopecia-areata
#4
REVIEW
Yetan Shi, Sheng Wan, Xiuzu Song
Alopecia areata refers to an autoimmune illness indicated by persistent inflammation. The key requirement for alopecia areata occurrence is the disruption of immune-privileged regions within the hair follicles. Recent research has indicated that neuropeptides play a role in the damage to hair follicles by triggering neurogenic inflammation, stimulating mast cells ambient the follicles, and promoting apoptotic processes in keratinocytes. However, the exact pathogenesis of alopecia areata requires further investigation...
April 11, 2024: Journal of Dermatology
https://read.qxmd.com/read/38605458/marked-effect-of-larotrectinib-on-primary-cutaneous-secretory-carcinoma-a-case-report
#5
LETTER
Kazuma Hayakawa, Ryokichi Irisawa, Rika Umefune, Kenichiro Mae, Yoshihisa Shimada, Reisuke Takahashi, Toshitaka Nagao, Kazutoshi Harada
No abstract text is available yet for this article.
April 11, 2024: Journal of Dermatology
https://read.qxmd.com/read/38605448/in-vivo-and-ex-vivo-tests-for-culprit-drugs-identification-in-severe-cutaneous-adverse-drugs-reactions
#6
JOURNAL ARTICLE
P Sittiwattanawong, K Kantikosum, K Charoenchaipiyakul, S Pootongkam, P Asawanonda, S J Kerr, P Thantiworasit, P Sodsai, N Hirankarn, J Klaewsongkram, P Rerknimitr
Drug causality assessment in severe cutaneous adverse reactions (SCARs) remains challenging. We investigated the usefulness of in-vivo drug patch tests (PT), ex-vivo interferon (IFN)-γ enzyme-linked immunospot (ELISpot) assay, and lymphocyte transformation test (LTT) in 30 SCARs patients within the past 36 months. Drug PT yielded a 20% positivity rate (n = 6), while IFN-γ ELISpot and LTT showed positive rates of 56.67% (n = 17) and 41.38% (n = 12), respectively...
April 11, 2024: Journal of Dermatology
https://read.qxmd.com/read/38605447/genetic-mutations-in-pyoderma-gangrenosum-hidradenitis-suppurativa-and-associated-autoinflammatory-syndromes-insights-into-pathogenic-mechanisms-and-shared-pathways
#7
LETTER
Chiara Moltrasio, Paola Maura Tricarico, de Moura Rodrigues Ronald, Brandão Lucas, Crovella Sergio, Angelo Valerio Marzano
No abstract text is available yet for this article.
April 11, 2024: Journal of Dermatology
https://read.qxmd.com/read/38605436/cellulitis-with-pseudomonas-putida-bacteremia-in-a-patient-with-autoimmune-hepatitis-a-case-report
#8
LETTER
Hiroto Ono, Fumiaki Taga, Reimon Yamaguchi, Yoshitsugu Iinuma, Akira Shimizu
No abstract text is available yet for this article.
April 11, 2024: Journal of Dermatology
https://read.qxmd.com/read/38605435/expression-of-phosphorylated-janus-kinase-1-and-il-4r%C3%AE-by-dermal-basophils-and-epidermal-keratinocytes-in-atopic-dermatitis-associated-prurigo-nodules-a-case-report
#9
LETTER
Riichiro Sugiura, Takashi Hashimoto, Satoshi Okuno, Takahiro Satoh
No abstract text is available yet for this article.
April 11, 2024: Journal of Dermatology
https://read.qxmd.com/read/38605433/a-rare-case-of-metastatic-extramammary-paget-disease-developing-transfusion-related-acute-lung-injury-during-chemotherapy
#10
LETTER
Yu Kurokami, Chigusa Yamashita, Kazunori Yokoi, Kyoko Tonomura, Yosuke Ishitsuka, Takeshi Yoshida, Yukiko Koyama, Yuji Fujino, Manabu Fujimoto, Atsushi Tanemura
No abstract text is available yet for this article.
April 11, 2024: Journal of Dermatology
https://read.qxmd.com/read/38587252/erythema-nodosum-of-the-extremities-following-dupilumab-treatment-in-a-patient-with-atopic-dermatitis
#11
LETTER
Yuka Hanami, Toshiyuki Yamamoto
No abstract text is available yet for this article.
April 8, 2024: Journal of Dermatology
https://read.qxmd.com/read/38587235/herpes-simplex-virus-infection-with-a-marginal-nikolsky-sign-in-an-immunocompromised-patient
#12
LETTER
Eriko Takayama, Akiko Yoshioka
No abstract text is available yet for this article.
April 8, 2024: Journal of Dermatology
https://read.qxmd.com/read/38558466/prevalence-and-risk-factors-for-onychomycosis-in-acute-care-dermatology-wards
#13
JOURNAL ARTICLE
Tsuyoshi Inoue, Daisuke Watabe, Maiko Furukawa, Maki Goto, Hirofumi Kamada, Yuri Sato, Nobuyuki Arakawa, Shinpei Miura, Toshiki Sato, Shinji Yasuhira, Yuichiro Tsunemi, Hiroo Amano
We conducted a cross-sectional study on the clinical and mycological features of onychomycosis in patients in the dermatology ward of Iwate Medical University Hospital, an acute care hospital. Of the 226 hospitalized patients, 73 (32.3%) had onychomycosis and 61 (26.9%) were diagnosed after admission. The toenail was the most common site of onychomycosis (94.5%), while toenail plus fingernail and fingernail only sites were 4.1% and 1.4%, respectively. The most common clinical form of onychomycosis was distal and lateral subungual onychomycosis (79%) with Trichophyton rubrum (66...
April 1, 2024: Journal of Dermatology
https://read.qxmd.com/read/38558381/a-case-of-plasma-cell-vulvitis-successfully-treated-with-crisaborole
#14
LETTER
Yimin He, Mingyuan Xu, Nanhui Wu, Fei Wu, Changchang Li, Ying Gao, Yeqiang Liu
No abstract text is available yet for this article.
April 1, 2024: Journal of Dermatology
https://read.qxmd.com/read/38558228/intractable-nocardial-mycetoma-with-possible-colonisation-by-candida-species
#15
JOURNAL ARTICLE
Ayano Sumioki, Kanami Saito, Haruto Nishida, Akira Nishizono, Yuji Miyamoto, Norihisa Ishii, Masataro Hiruma, Kazutoshi Shibuya, Takashi Yaguchi, Yutaka Hatano
A Japanese male in his 30s with no underlying medical condition presented with painless nodules after being bitten by a dog during a stay in Bali, Indonesia, 7 years earlier. He was referred to our department with multiple ulcers, nodules, and masses on the right leg. The final diagnosis was mycetoma caused by Nocardia vulneris, which may have been exacerbated by colonization of Candida parapsilosis and C. tropicalis as these yeasts were isolated by culture from the tissue. Treatment with minocycline hydrochloride and sulfamethoxazole trimethoprim showed partial efficacy, but the addition of posaconazole achieved significant efficacy...
April 1, 2024: Journal of Dermatology
https://read.qxmd.com/read/38558171/reliability-validity-and-sensitivity-of-the-japanese-version-of-the-university-of-california-los-angeles-scleroderma-clinical-trial-consortium-gastrointestinal-tract-instrument-application-to-efficacy-assessment-of-intravenous-immunoglobulin-administration
#16
JOURNAL ARTICLE
Kazuki M Matsuda, Eiki Sugimoto, Yoshiaki Ako, Marie Kitamura, Mai Miyahara, Hirohito Kotani, Yuta Norimatsu, Teruyoshi Hisamoto, Ai Kuzumi, Takemichi Fukasawa, Shinichi Sato, Ayumi Yoshizaki
This study aimed to develop and assess the reliability, validity, and sensitivity of the Japanese version of the University of California Los Angeles Scleroderma Clinical Trial Consortium gastrointestinal tract (GIT) Instrument 2.0 (the GIT score), as an evaluation tool for GIT symptoms in systemic sclerosis (SSc). The Japanese version of the GIT score was constructed using the forward-backward method. The reliability and validity of this instrument were evaluated in a cohort of 38 SSc patients. Correlation analysis was conducted to assess the relationship between the GIT score and existing patient-reported outcome measures...
April 1, 2024: Journal of Dermatology
https://read.qxmd.com/read/38558105/proteasome-inhibitor-associated-histiocytoid-sweet-s-syndrome-clinical-and-histological-similarities-to-nakajo-nishimura-syndrome-suggest-a-potential-mechanism
#17
JOURNAL ARTICLE
Ryang Cho, Saeko Nakajima, Yo Kaku, Junko Tezuka, Masakazu Fujimoto, Naotomo Kambe, Kenji Kabashima
Histiocytoid Sweet's syndrome (HSS) is a variant of Sweet's syndrome (SS) that clinically resembles SS but differs histologically by infiltrates, predominantly composed of immature cells of the myeloid lineage. Medications such as proteasome inhibitors have been reported to cause HSS but there has been little discussion on the underlying mechanism. Here we report two cases of HSS associated with a proteasome inhibitor. Both patients were on ixazomib for the treatment of multiple myeloma and presented with acute erythematous plaques on the upper half of the body...
April 1, 2024: Journal of Dermatology
https://read.qxmd.com/read/38558035/sars-cov-2-spike-protein-found-in-the-acrosyringium-and-eccrine-gland-of-repetitive-miliaria-like-lesions-in-a-woman-following-mrna-vaccination
#18
LETTER
Shigetoshi Sano, Mayuko Yamamoto, Reiko Kamijima, Hozumi Sano
No abstract text is available yet for this article.
April 1, 2024: Journal of Dermatology
https://read.qxmd.com/read/38529706/long-term-follow-up-results-from-keynote-041-phase-1b-study-of-pembrolizumab-in-japanese-patients-with-advanced-melanoma
#19
JOURNAL ARTICLE
Kenji Yokota, Tatsuya Takenouchi, Yasuhiro Fujisawa, Satoshi Fukushima, Hiroshi Uchi, Takashi Inozume, Yoshio Kiyohara, Hisashi Uhara, Kazuhiko Nakagawa, Hiroshi Furukawa, Shirong Han, Masaru Watanabe, Kazuo Noguchi, Naoya Yamazaki
Pembrolizumab demonstrated an acceptable safety profile and promising antitumor activity in Japanese patients with advanced melanoma in the phase 1b KEYNOTE-041 (Study of Pembrolizumab [MK-3475] in Participants With Advanced Melanoma) trial. To evaluate the long-term efficacy and safety of pembrolizumab in Japanese patients with advanced melanoma in KEYNOTE-041. The current analysis reports results of additional follow-up of approximately 12 months since the initial analysis. Eligible patients had locally advanced (unresectable stage III) or metastatic (stage IV) melanoma not amenable to local therapy and had received two or fewer prior systemic therapies...
March 26, 2024: Journal of Dermatology
https://read.qxmd.com/read/38525829/plantar-keratoderma-and-curly-hair-as-a-diagnostic-clue-of-cardiomyopathy-risk
#20
Stine Bjørn Gram, Klaus Brusgaard, Anette Bygum, Alex Hørby Christensen, Lilian Bomme Ousager
No abstract text is available yet for this article.
March 25, 2024: Journal of Dermatology
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