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Journal of Dermatology

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https://read.qxmd.com/read/30768822/revival-of-favus-in-japan-caused-by-trichophyton-schoenleinii
#1
Kentaro Iwasa, Kohei Ogawa, Hiroaki Azukizawa, Hiroshi Tanabe, Tomoyuki Iwanaga, Kazushi Anzawa, Takashi Mochizuki, Hideo Asada
Favus is a type of dermatophytosis known to produce yellow scutula around hair follicles. Most cases of this disease worldwide are infections of Trichophyton schoenleinii. Favus has rarely been reported in Japan throughout the last four decades, and T. schoenleinii has not been clinically isolated in any case during the period. Here, we report a case of favus of vellus hair observed in a 63-year-old Japanese woman. Fungal culture showed negative; however, we detected fungal elements in the crust and hair bulbs by Grocott staining...
February 15, 2019: Journal of Dermatology
https://read.qxmd.com/read/30768808/terbinafine-resistant-strain-of-trichophyton-interdigitale-strain-isolated-from-a-tinea-pedis-patient
#2
Junichiro Hiruma, Hiroyuki Kitagawa, Hiromitsu Noguchi, Rui Kano, Masataro Hiruma, Hiroshi Kamata, Kazutoshi Harada
Trichophyton interdigitale is an anthropophilic species that is frequently isolated from tinea unguium and tinea pedis throughout the world. In the present study, antifungal susceptibility testing was performed on T. interdigitale isolates from Japanese patients (isolated in 2017-2018; 24 strains) to assess itraconazole (ITZ) and terbinafine (TRF) susceptibility of these strains. E-test determinations revealed that the mean ITZ minimum inhibitory concentration (MIC) of the 24 strains was 0.023 mg/L (range, 0...
February 15, 2019: Journal of Dermatology
https://read.qxmd.com/read/30768803/relationship-between-dermoscopy-and-pathology-in-a-case-of-clonal-type-pigmented-bowen-s-disease-observation-with-vertical-view-dermoscopy
#3
Mika Yamanaka-Takaichi, Toshiyuki Ozawa, Nao Kusutani, Junko Sowa-Osako, Masaru Tanaka, Yozo Murata, Yuki Kubo, Masahiko Ohsawa, Daisuke Tsuruta, Hiroshi Sakai
Pigmented Bowen's disease (pBD) is a subtype of Bowen's disease, which presents clinically as a well-circumscribed, hyperpigmented plaque. Its clinical manifestations are not fully characterized, and differential diagnoses include various pigmented skin lesions. Dermoscopy could be useful for the diagnosis, although nothing has been reported on the dermoscopic features of clonal-type pBD. We herein report a first case of clonal-type pBD on the sole and its dermoscopic features. Dermoscopy showed brown to blue-gray dots/globules and focally anastomosing lines on the non-weight-bearing area, while the weight-bearing area had a brown to blue-gray fibrillar-like pattern...
February 15, 2019: Journal of Dermatology
https://read.qxmd.com/read/30758883/oral-lichen-planus-and-lichen-planopilaris-complicated-with-thymoma
#4
LETTER
Kazuya Teramura, Takeshi Kato, Junko Nishikawa, Takeshi Nakanishi, Toshihiro Tanaka, Noriki Fujimoto
No abstract text is available yet for this article.
February 13, 2019: Journal of Dermatology
https://read.qxmd.com/read/30758879/severe-bullous-pemphigoid-in-a-metastatic-lung-cancer-patient-treated-with-pembrolizumab
#5
LETTER
Eriko Adachi, Tetsuya Honda, Shoko Nonoyama, Hiroyuki Irie, Kentaro Yamamura, Atsushi Otsuka, Kenji Kabashima
No abstract text is available yet for this article.
February 13, 2019: Journal of Dermatology
https://read.qxmd.com/read/30758872/refractory-warts-successfully-treated-with-a-nitric-zinc-complex-solution
#6
LETTER
Eduardo Rozas-Muñoz, Joan Mir-Bonafé, Jaime Piquero-Casals
No abstract text is available yet for this article.
February 13, 2019: Journal of Dermatology
https://read.qxmd.com/read/30758866/biologic-induced-urticaria-due-to-polysorbate-20
#7
LETTER
Maiko Kato, Naoki Oiso, Shusuke Uchida, Shigeto Yanagihara, Hiroyuki Sano, Yuji Tohda, Akira Kawada
No abstract text is available yet for this article.
February 13, 2019: Journal of Dermatology
https://read.qxmd.com/read/30758859/efficacy-of-combined-radiotherapy-and-anti-programmed-death-1-therapy-in-acral-and-mucosal-melanoma
#8
Junji Kato, Tokimasa Hida, Masanori Someya, Sayuri Sato, Masahide Sawada, Kohei Horimoto, Mao Fujioka, Tomoyuki Minowa, Yoshiyuki Matsui, Takaaki Tsuchiya, Mio Kitagawa, Kensei Nakata, Koh-Ichi Sakata, Toshihiko Torigoe, Hisashi Uhara
Some studies showed that clinical response to immune check point inhibitors is lower in acral and mucosal melanoma than in cutaneous melanoma. Although the synergistic effect of radiotherapy (RT) and ipilimumab has been reported in patients with brain metastasis, the efficacy of combined RT and anti-programmed death 1 (PD-1) therapy for acral and mucosal melanoma is unclear. The present study aimed to evaluate the efficacy of combined RT and anti-PD-1 therapy for acral and mucosal melanoma. We retrospectively analyzed patients with acral or mucosal melanoma who were treated with anti-PD-1 and RT at Sapporo Medical University Hospital...
February 13, 2019: Journal of Dermatology
https://read.qxmd.com/read/30756423/atopic-dermatitis-disease-registry-in-japanese-adult-patients-with-moderate-to-severe-atopic-dermatitis-address-j-baseline-characteristics-treatment-history-and-disease-burden
#9
Norito Katoh, Hidehisa Saeki, Yoko Kataoka, Takafumi Etoh, Satoshi Teramukai, Hiroki Takagi, Yuki Tajima, Marius Ardeleanu, Elena Rizova, Kazuhiko Arima
Moderate to severe atopic dermatitis (AD) has a high disease burden and a significant effect on quality of life. Observational studies are necessary to determine the patient disease burden and long-term disease control in the Japanese population. ADDRESS-J is a non-interventional, observational registry of adult Japanese patients with moderate to severe AD. Herein, we report baseline data from the ADDRESS-J study describing disease characteristics and current treatment practices. At baseline, 300 adult AD patients with Investigator's Global Assessment (IGA) scores (range, 0-4) of 3 (moderate) or 4 (severe) whose treatments for AD were intensified, were assessed for clinical and patient-reported outcomes and current AD treatments...
February 13, 2019: Journal of Dermatology
https://read.qxmd.com/read/30740762/sex-differences-of-chinese-patients-with-primary-localized-cutaneous-amyloidosis
#10
LETTER
Ping Lu, Fangfang Wu, Maoqiang Man, Zhili Rong, Yuling Zhang, Bin Yang
No abstract text is available yet for this article.
February 11, 2019: Journal of Dermatology
https://read.qxmd.com/read/30724385/changes-in-inflammatory-markers-correlated-with-increased-testosterone-after-laparoscopic-sleeve-gastrectomy-in-obese-chinese-men-with-acanthosis-nigricans
#11
Cuiling Zhu, Fangyun Mei, Jingyang Gao, Donglei Zhou, Liesheng Lu, Shen Qu
Bariatric surgery is an effective method for severe obesity and its related comorbidities. This study was performed to explore the alterations of sex hormones and inflammatory markers following laparoscopic sleeve gastrectomy (LSG) among obese Chinese men with acanthosis nigricans (AN). Sixty-five obese men who underwent LSG were enrolled, comprising simple obesity without AN (OB group, n = 20) and obesity with AN (AN group, n = 45). There were 31 healthy male controls with normal body mass index (BMI) included...
February 6, 2019: Journal of Dermatology
https://read.qxmd.com/read/30719747/b-cell-lymphoblastic-leukemia-lymphoma-in-infants-report-of-two-cases-on-the-face
#12
LETTER
Takahiro Kiyohara, Kaoru Makimura, Sei Nakamaru, Mari Miyamoto, Takako Shijimaya, Naoko Nagano, Hirotsugu Tanimura
No abstract text is available yet for this article.
February 5, 2019: Journal of Dermatology
https://read.qxmd.com/read/30719729/varied-responses-to-and-efficacies-of-hydroxychloroquine-treatment-according-to-cutaneous-lupus-erythematosus-subtypes-in-japanese-patients
#13
Yasushi Ototake, Yukie Yamaguchi, Miwa Kanaoka, Asami Akita, Nobuaki Ikeda, Michiko Aihara
Hydroxychloroquine is recommended as the first-line systemic treatment for cutaneous lupus erythematosus (CLE) in Western countries, and it was approved in Japan in 2016. However, the efficacy of hydroxychloroquine in various cutaneous lupus erythematosus subtypes in Japanese patients has not been elucidated to date. Therefore, we investigated the efficacy of hydroxychloroquine for the treatment of cutaneous manifestations according to CLE subtypes in Japanese patients. We enrolled 35 patients (29 diagnosed with systemic lupus erythematosus and six with CLE) in this retrospective study...
February 5, 2019: Journal of Dermatology
https://read.qxmd.com/read/30719722/sudden-elevation-of-plasma-d-dimer-levels-induced-by-the-combination-therapy-of-dabrafenib-and-trametinib-report-of-two-cases
#14
Saki Akino, Hiroyuki Ohashi, Tatsuro Okano, Sora Takeuchi, Tamihiro Kawakami, Yoshinao Soma, Takafumi Kadono
The combination therapy of dabrafenib and trametinib revolutionized the treatment for BRAF V600-mutated melanoma. Various adverse events have been reported for this treatment, most notably fever. Herein, we report two cases of novel an adverse event, namely sudden and significant elevation of plasma D-dimer level induced by this therapy. In the first case, the remarkable elevation of plasma D-dimer level up to 87.4 mg/dL was noted on day 11, and in the second case, the plasma D-dimer level reached 125.5 mg/dL on day 25...
February 5, 2019: Journal of Dermatology
https://read.qxmd.com/read/30714650/peripheral-blood-eosinophilia-is-associated-with-the-presence-of-skin-ulcers-in-patients-with-systemic-sclerosis
#15
Tomoyuki Hara, Takaharu Ikeda, Yutaka Inaba, Kayo Kunimoto, Naoya Mikita, Chikako Kaminaka, Nobuo Kanazawa, Yuki Yamamoto, Kayoko Tabata, Takao Fujii, Masatoshi Jinnin
The role of eosinophil in systemic sclerosis (SSc) is still controversial. In the present study, the relationship between skin ulcers and peripheral blood eosinophilia were analyzed in patients with SSc. We retrospectively investigated the clinical records of all patients who were diagnosed with SSc on the basis of American College of Rheumatology/European League Against Rheumatism 2013 criteria, and were followed up for more than 2 years at Wakayama Medical University. As a result, maximum eosinophil counts during the 2-year follow-up period were 20-983/mm3 (median, 270), whereas maximum eosinophil percentages were 0...
February 4, 2019: Journal of Dermatology
https://read.qxmd.com/read/30714643/successful-treatment-of-refractory-cutaneous-lupus-vasculitis-with-i-v-immunoglobulin
#16
LETTER
Risa Takamuki, Naoko Okiyama, Sae Inoue, Ruriko Endo, Yuya Kondo, Yusuke Chino, Takayuki Sumida, Manabu Fujimoto
No abstract text is available yet for this article.
February 4, 2019: Journal of Dermatology
https://read.qxmd.com/read/30714641/orthotic-treatment-for-refractory-plantar-ulcers-using-distribution-assessments-of-sensory-disturbance-and-dynamic-plantar-pressure-in-patients-with-hansen-s-disease-a-case-series
#17
LETTER
Syoichi Tashiro, Yuki Oku, Naoki Gotou, Takahiro Sugano, Keita Kikuhara, Takuya Nakamura, Hiromi Suzuki, Norio Endo, Chieko Miyata, Katsuhiro Mizuno, Norihisa Ishii, Yutaka Asato
No abstract text is available yet for this article.
February 4, 2019: Journal of Dermatology
https://read.qxmd.com/read/30714633/claudin-reduction-may-relate-to-an-impaired-skin-barrier-in-rosacea
#18
Zhili Deng, Mengting Chen, Hongfu Xie, Dan Jian, San Xu, Qinqin Peng, Ke Sha, Yingzi Liu, Yiya Zhang, Wei Shi, Ji Li
Rosacea is a chronic inflammatory skin disorder whose pathophysiological mechanism remains largely unknown. Although recent studies have revealed the hypersensitivity of the skin towards chemical, thermal and biological stimuli, there is no direct molecular evidence suggesting the skin barrier is impaired in rosacea. In this study, we demonstrated that the mRNA levels of most claudins (CLDN), the main components of tight junctions determining the major barrier of the paracellular pathway between epithelial cells, were lowered in lesional skin of rosacea patients, especially with erythematotelangiectatic (ETR) and papulopustular (PPR) subtypes...
February 4, 2019: Journal of Dermatology
https://read.qxmd.com/read/30710379/case-report-of-cutaneous-nodule-caused-by-gordonia-bronchialis-in-an-immunocompetent-patient-after-receiving-acupuncture
#19
Myoung Eun Choi, Chang Jin Jung, Chong Hyun Won, Sung Eun Chang, Mi Woo Lee, Jee Ho Choi, Woo Jin Lee
Gordonia species were recently found to cause human infection. Most Gordonia bronchialis infections are associated with sternal wounds and foreign bodies. Here, we present a case of a firm cutaneous nodule caused by G. bronchialis on an immunocompetent patient's lower extremity after receiving acupuncture. Our present case indicates that spontaneous cutaneous infection of G. bronchialis can develop even in a healthy patient. With the popularity of complementary and alternative medicine, physicians should be aware that G...
February 1, 2019: Journal of Dermatology
https://read.qxmd.com/read/30701580/severe-genital-frostbite-due-to-improper-use-of-an-aerosol-spray-a-case-of-raising-awareness-of-the-risk-of-skin-necrosis-with-aerosol-propellants
#20
LETTER
Yuko Kurosaki, Osamu Negi, Kenji Takamori, Yasushi Suga
No abstract text is available yet for this article.
January 31, 2019: Journal of Dermatology
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