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Journal Article
Research Support, U.S. Gov't, P.H.S.
Prolonged differential wound hyperalgesia after an interval of unilateral epidural blockade during lower abdominal surgery.
Anesthesia and Analgesia 2005 May
We assessed postoperative pain at rest and with movement along with wound hyperalgesia in a patient who had undergone lower abdominal surgery under general anesthesia with a unilateral epidural block that persisted throughout surgery and in whom the epidural catheter was replaced immediately afterward. Pain and wound hyperalgesia were consistently greater on the "unblocked" side for the 3-wk period of observation. Thus, even imperfect intraoperative attenuation of noxious stimuli can lead to persistent reductions in postoperative pain.
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