Anti-inflammatory and antinociceptive activities of Trewia polycarpa roots

D Chamundeeswari, J Vasantha, S Gopalakrishnan, E Sukumar
Fitoterapia 2004, 75 (7): 740-4
The alcoholic extract of Trewia polycarpa roots, when administered orally to rats at doses of 50-400 mg/kg, exhibited a dose-dependent anti-inflammatory activity in both acute and chronic models. It also showed a significant antinociceptive action mice in the dose range of 25-200 mg/kg. The extract did not reveal any toxicity in rats up to a dose of 3.2 g/kg (p.o.). It showed the presence of terpenoids, alkaloids, flavonoids, quinones and glycosides on phytochemical screening.

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