Zhe-Yue Han, Jia-Tong Wu, Yu-Xuan Lin, Yu Bi, Anam Naseem, Zhi-Chao Hao, Juan Pan, Wei Guan, Hai-Xue Kuang, Qing-Shan Chen, Li-Li Zhang, Yan Liu, Bing-You Yang
Seven new triterpenoids, named Adeterpenoids A-G (1-7) and eight known compounds (8-15), were isolated from 70% ethanol extract of the roots of Adenophora tetraphylla (Thub.) Fisch. The compounds from it were separated by column chromatography techniques such as silica gel, ODS, and preparative liquid chromatography. Their structures were clarified based on extensive spectral analysis (1D, 2D-NMR, HR-ESI-MS, IR, UV, and CD) and comparison with the literature. At the same time, all compounds were evaluated for their cytotoxic activity against the LN229 (human glioma cell line)...
March 16, 2024: Fitoterapia