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Research Support, Non-U.S. Gov't
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Thalamic deep brain stimulation activates the cerebellothalamocortical pathway.

G F Molnar, A Sailer, C A Gunraj, A E Lang, A M Lozano, R Chen
Neurology 2004 September 15
To investigate the mechanism of action of deep brain stimulation (DBS), the authors studied the effects of thalamic DBS on the cerebellothalamocortical (CTC) pathway. With DBS turned off, excitability of the CTC pathway was reduced. Turning DBS on resulted in facilitation of the CTC pathway. Therefore, thalamic DBS appears to activate rather than inhibit the target area.

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