journal
https://read.qxmd.com/read/33441460/glass-half-full-preservation-of-memory-in-alzheimer-related-primary-progressive-aphasia
#1
EDITORIAL
Seyed Ahmad Sajjadi, Sharon Ash, Stefano Cappa
No abstract text is available yet for this article.
January 13, 2021: Neurology
https://read.qxmd.com/read/33441459/pearls-oy-ster-upbeat-nystagmus-and-quadriplegia-in-a-young-girl-with-bilateral-medial-medullary-syndrome-mms
#2
Intan Aaroni Md Isa, Sanihah Abdul Halim, Chee Yong Chuan
No abstract text is available yet for this article.
January 13, 2021: Neurology
https://read.qxmd.com/read/33441458/deep-medullary-vein-thrombosis-in-neonate-a-peculiar-mri-pattern
#3
Ana Paula Alves Fonseca, Ruann Melo de Carvalho, Mário Padula, Rita de Cassia Maciel Pincerato
No abstract text is available yet for this article.
January 13, 2021: Neurology
https://read.qxmd.com/read/33441457/teaching-neuroimages-magnetic-susceptibility-weighted-imaging-mapped-the-migratory-route-of-a-paragonimus-in-brain
#4
Ke Yu, Mingjie Zhang
No abstract text is available yet for this article.
January 13, 2021: Neurology
https://read.qxmd.com/read/33441456/idiopathic-recurring-stupor-an-unusual-clinical-condition-responding-to-flumazenil
#5
Andrea Gómez García, Inmaculada Navas Vinagre, Antonio Herranz Bárcenas
No abstract text is available yet for this article.
January 13, 2021: Neurology
https://read.qxmd.com/read/33441455/association-of-initial-maximal-motor-ability-with-long-term-functional-outcome-in-patients-with-col6-related-dystrophies
#6
Daniel Natera-de Benito, A Reghan Foley, Cristina Domínguez-González, Carlos Ortez, Minal Jain, Aron Mebrahtu, Sandra Donkervoort, Ying Hu, Margaret Fink, Pomi Yun, Tracy Ogata, Julita Medina, Meritxell Vigo, Katherine G Meilleur, Meganne E Leach, Jahannaz Dastgir, Jordi Díaz-Manera, Laura Carrera-García, Jessica Expósito-Escudero, Macarena Alarcon, Daniel Cuadras, Elena Montiel-Morillo, José C Milisenda, Raul Dominguez-Rubio, Montse Olivé, Jaume Colomer, Cristina Jou, Cecilia Jimenez-Mallebrera, Carsten G Bönnemann, Andres Nascimento
OBJECTIVE: To accurately categorize the phenotypes of individuals with collagen VI-related dystrophies (COL6-RDs) during the first years of life in order to predict long-term motor function and pulmonary function, provide phenotype-specific anticipatory care and improve clinical trial readiness. METHODS: This retrospective, multicenter, international study analyzed the relationship of long-term motor and pulmonary function with the initial maximal motor ability achieved in individuals with COL6-RD...
January 13, 2021: Neurology
https://read.qxmd.com/read/33441454/memory-resilience-in-alzheimer-s-disease-with-primary-progressive-aphasia
#7
M-Marsel Mesulam, Christina Coventry, Alan Kuang, Eileen H Bigio, Qinwen Mao, Margaret E Flanagan, Tamar Gefen, Jaiashre Sridhar, Changiz Geula, Hui Zhang, Sandra Weintraub, Emily J Rogalski
OBJECTIVE: To determine whether memory is preserved longitudinally in primary progressive aphasia (PPA) associated with Alzheimer's disease (AD), and to identify potential factors that maintain memory despite underlying neurofibrillary degeneration of mediotemporal memory areas. METHODS: Longitudinal memory assessment in 17 PPA patients with autopsy or biomarker evidence of AD (PPA-AD) and 14 patients with amnestic dementia of the Alzheimer type with AD at autopsy (DAT-AD)...
January 13, 2021: Neurology
https://read.qxmd.com/read/33441453/role-of-the-nucleus-basalis-as-a-key-network-node-in-temporal-lobe-epilepsy
#8
Hernán F J González, Saramati Narasimhan, Graham W Johnson, Kristin E Wills, Kevin F Haas, Peter E Konrad, Catie Chang, Victoria L Morgan, Mikail Rubinov, Dario J Englot
OBJECTIVE: To determine if nucleus basalis of Meynert (NBM) may be a key network structure of altered functional connectivity in temporal lobe epilepsy (TLE), we examined fMRI with network based analyses. METHODS: We acquired resting-state fMRI in 40 adults with TLE and 40 matched healthy control participants. We calculated functional connectivity of NBM and used multiple complementary network based analyses to explore the importance of NBM in TLE networks without biasing our results by our approach...
January 13, 2021: Neurology
https://read.qxmd.com/read/33441452/association-of-gray-matter-atrophy-patterns-with-clinical-phenotype-and-progression-in-multiple-sclerosis
#9
Maria A Rocca, Paola Valsasina, Alessandro Meani, Claudio Gobbi, Chiara Zecca, Alex Rovira, Jaume Sastre-Garriga, Hugh Kearney, Olga Ciccarelli, Lucy Matthews, Jacqueline Palace, Antonio Gallo, Alvino Bisecco, Carsten Lukas, Barbara Bellenberg, Frederik Barkhof, Hugo Vrenken, Paolo Preziosa, Massimo Filippi
OBJECTIVES: Grey matter (GM) involvement is clinically relevant in multiple sclerosis (MS). Using source-based morphometry (SBM), we characterized GM atrophy and its 1-year evolution across different MS phenotypes. METHODS: Clinical and MRI data were obtained at 8 European sites from 170 healthy controls (HCs) and 398 MS patients (34 clinically isolated syndromes [CIS], 226 relapsing-remitting [RR], 95 secondary progressive [SP] and 43 primary progressive [PP] MS)...
January 13, 2021: Neurology
https://read.qxmd.com/read/33431519/leisure-activity-participation-and-risk-of-dementia-an-18-year-follow-up-of-the-whitehall-ii-study
#10
(no author information available yet)
No abstract text is available yet for this article.
January 11, 2021: Neurology
https://read.qxmd.com/read/33431518/-correction-long-term-employment-outcomes-after-epilepsy-surgery-in-childhood
#11
(no author information available yet)
No abstract text is available yet for this article.
January 11, 2021: Neurology
https://read.qxmd.com/read/33431517/association-of-bone-mineral-density-to-cerebral-small-vessel-disease-burden
#12
Jeong-Min Kim, Dr Kwang-Yeol Park, Dr Hye Ryoun Kim, Dr Hwa Young Ahn, Dr Leonardo Pantoni, Dr Moo-Seok Park, Dr Su-Hyun Han, Dr Hae-Bong Jung, Dr Jaehan Bae Dr
OBJECTIVE: To test the hypothesis that bone mineral loss is mechanistically related to cerebral small vessel disease (SVD), we investigated the relationship between bone mineral density and the prevalence and intensity of SVD among stroke patients. METHODS: We analyzed data of 1190 consecutive stroke patients older than 50 years who underwent both brain MRI and dual-energy X-ray absorptiometry from the stroke registry of Chung-Ang University Hospital in Seoul, Korea...
January 11, 2021: Neurology
https://read.qxmd.com/read/33431516/quality-improvement-in-neurology-headache-quality-measurement-set
#13
(no author information available yet)
No abstract text is available yet for this article.
January 11, 2021: Neurology
https://read.qxmd.com/read/33408152/networking-not-working-functional-connectivity-to-predict-post-stroke-cognition
#14
EDITORIAL
Amy Brodtmann, Argye Hillis
No abstract text is available yet for this article.
January 6, 2021: Neurology
https://read.qxmd.com/read/33408151/painful-recurrent-diplopia-caused-by-medial-rectus-cysticercosis
#15
Emmanuelle Moret, François-Xavier Borruat
No abstract text is available yet for this article.
January 6, 2021: Neurology
https://read.qxmd.com/read/33408150/validation-of-the-alzheimer-disease-dementia-conversion-related-pattern-as-an-atn-biomarker-of-neurodegeneration
#16
Ganna Blazhenets, Lars Frings, Yilong Ma, Arnd Sörensen, David Eidelberg, Jens Wiltfang, Philipp T Meyer
OBJECTIVE: To determine whether the Alzheimer's disease dementia conversion-related pattern (ADCRP) on [18 F]FDG PET can serve as a valid predictor for the development of Alzheimer's disease dementia, the individual expression of the ADCRP (subject score) and its prognostic value were examined in subjects with mild cognitive impairment and biologically defined Alzheimer's disease. METHODS: 269 subjects with available [18 F]FDG PET, [18 F]AV-45 PET, phosphorylated and total tau in CSF, and neurofilament light chain in plasma were included...
January 6, 2021: Neurology
https://read.qxmd.com/read/33408149/high-frequency-oscillations-in-epilepsy-what-have-we-learned-and-what-needs-to-be-addressed
#17
REVIEW
Zhuying Chen, Matias I Maturana, Anthony N Burkitt, Mark J Cook, David B Grayden
For the past two decades, high-frequency oscillations (HFOs) have been enthusiastically studied by the epilepsy community. Emerging evidence shows that HFOs harbour great promise to delineate epileptogenic brain areas and possibly predict the likelihood of seizures. Investigations into HFOs in clinical epilepsy have advanced from small retrospective studies relying on visual identification and correlation analysis to larger prospective assessments using automatic detection and prediction strategies. While most studies have yielded promising results, some have revealed significant obstacles to clinical application of HFOs, thus raising debate about the reliability and practicality of HFOs as clinical biomarkers...
January 6, 2021: Neurology
https://read.qxmd.com/read/33408148/mild-cognitive-impairment-at-risk-for-lewy-body-dementia
#18
Qin Chen, Val J Lowe, Bradley F Boeve, Scott A Przybelski, Toji Miyagawa, Matthew L Senjem, Clifford R Jack, Timothy G Lesnick, Walter K Kremers, Julie A Fields, Hoon-Ki Min, Christopher G Schwarz, Jeffrey L Gunter, Jonathan Graff-Radford, Rodolfo Savica, David S Knopman, David Jones, Tanis J Ferman, Neill R Graff-Radford, Ronald C Petersen, Kejal Kantarci
OBJECTIVE: To determine the clinical phenotypes associated with the amyloid-β PET and dopamine transporter imaging (123 I-FP-CIT SPECT) findings in mild cognitive impairment (MCI) with the core clinical features of dementia with Lewy bodies (DLB; MCI-LB). METHODS: Patients with MCI who had at least one core clinical feature of DLB (n=34) were grouped into β-amyloid A+ or A- and 123 I-FP-CIT SPECT D+ or D- groups based on previously established abnormality cut points for A+ with Pittsburgh compound-B PET standardized uptake value ratio (PiB SUVR) ≥1...
January 6, 2021: Neurology
https://read.qxmd.com/read/33408147/temporal-dynamics-of-beta-amyloid-accumulation-in-aging-and-alzheimer-s-disease
#19
William J Jagust, Susan M Landau
OBJECTIVE: We performed this study to understand the time course of β-amyloid (Aβ) deposition in the brain, which is crucial for planning therapeutic trials of Aβ lowering therapies in Alzheimer's disease (AD). METHODS: Two samples of participants from the Alzheimer's disease neuroimaging initiative were studied with [18 F]Florbetapir (FBP) Aβ positron emission tomography (PET) and followed for up to 9 years. Sample A included 475 cognitively normal (CN) older people and those with mild cognitive impairment (MCI) and AD, and sample B included 220 CN Aβ- individuals...
January 6, 2021: Neurology
https://read.qxmd.com/read/33408146/association-of-csf-biomarkers-with-hippocampal-dependent-memory-in-preclinical-alzheimer-disease
#20
Alexandra N Trelle, Valerie A Carr, Edward N Wilson, Michelle S Swarovski, Madison P Hunt, Tyler N Toueg, Tammy T Tran, Divya Channappa, Nicole K Corso, Monica K Thieu, Manasi Jayakumar, Ayesha Nadiadwala, Wanjia Guo, Natalie J Tanner, Jeffrey D Bernstein, Celia P Litovsky, Scott A Guerin, Anna M Khazenzon, Marc B Harrison, Brian K Rutt, Gayle K Deutsch, Frederick T Chin, Guido A Davidzon, Jacob N Hall, Sharon J Sha, Carolyn A Fredericks, Katrin I Andreasson, Geoffrey A Kerchner, Anthony D Wagner, Elizabeth C Mormino
OBJECTIVE: To determine if memory tasks with demonstrated sensitivity to hippocampal function can detect variance related to preclinical Alzheimer's disease (AD) biomarkers, we examined associations between performance in three memory tasks and CSF Aβ42 /Aβ40 and p-tau181 in cognitively unimpaired older adults (CU). METHODS: CU enrolled in the Stanford Aging and Memory Study (N=153; age 68.78 ± 5.81 yrs; 94 female) completed a lumbar puncture and memory assessments...
January 6, 2021: Neurology
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