Emma M Coomans, Lotte A de Koning, Roos M Rikken, Sander C Verfaillie, Denise Visser, Anouk den Braber, Jori Tomassen, Marleen van de Beek, Lyduine E Collij, Afina W Lemstra, Albert D Windhorst, Frederik Barkhof, Sandeep S Golla, Pieter Jelle Visser, Philip Scheltens, Wiesje M van der Flier, Rik Ossenkoppele, Bart N Van Berckel, Elsmarieke van de Giessen
BACKGROUND AND OBJECTIVES: Recently, the US Food and Drug Administration approved the tau-binding radiotracer [18 F]flortaucipir and an accompanying visual read method to support the diagnostic process in cognitively impaired patients assessed for Alzheimer's disease (AD). Studies evaluating this visual read method are limited. Here, we evaluated the performance of the visual read method in participants along the AD continuum and dementia with Lewy Bodies (DLB) by determining its reliability, accordance with semi-quantitative analyses and associations with clinically relevant variables...
September 25, 2023: Neurology