LeAnn Boyce, Ahasan Harun, Gayle Prybutok, Victor R Prybutok
This research establishes a theoretical framework for evaluating antecedents of the information seeking behaviors of online forum participants with chronic obstructive pulmonary disease (COPD). We evaluated the proposed framework using partial least squares structural equation modeling (PLS-SEM) after gathering data using a cross-sectional survey. We subsequently assessed the framework using importance-performance map analysis (IPMA). Findings suggest that perceived ease of use does not singularly influence COPD forum users' information seeking behavior...
July 19, 2021: Health Promotion International
Tarek Abdel Latif Ghonimi, Mohamad Mahmood Alkad, Essa Abdulla Abuhelaiqa, Muftah M Othman, Musab Ahmed Elgaali, Rania Abdelaziz M Ibrahim, Shajahan M Joseph, Hassan Ali Al-Malki, Abdullah Ibrahim Hamad
CONTEXT: Patients on maintenance dialysis are more susceptible to COVID-19 and its severe form. We studied the mortality and associated risks of COVID-19 infection in dialysis patients in the state of Qatar. METHODS: This was an observational, analytical, retrospective, nationwide study. We included all adult patients on maintenance dialysis therapy who tested positive for COVID-19 (PCR assay of the nasopharyngeal swab) during the period from February 1, 2020, to July 19, 2020...
2021: PloS One
Daniel Stevens, Pantelis Andreou, Daniel Rainham
PURPOSE: Physical activity (PA) predicts important health outcomes in chronic obstructive pulmonary disease (COPD). In the general population, environmental factors have the potential to influence PA; however, data are limited in this clinical population. Therefore, we sought to investigate associations between the environment and PA, sedentary behavior, and self-rated health in COPD. METHODS: Sociodemographic, PA, sedentary behavior, and self-rated health data were collected from a prospective cohort of 418 individuals with COPD (65% female; 58 ± 8 yr), while environmental data were drawn from a national environmental data repository and individually matched to participant postal code...
July 20, 2021: Journal of Cardiopulmonary Rehabilitation and Prevention
Lisa G Wood
No abstract text is available yet for this article.
July 21, 2021: Respirology: Official Journal of the Asian Pacific Society of Respirology
Rafael Mesquita, Guilherme P F da Silva, Francisco Alessandro Braga do Nascimento, Marcelo Alcantara Holanda, Daniela Gardano Bucharles Mont'Alverne, Paulo Vinicius de Oliveira Junior, Daisy J A Janssen, Eanes Delgado Barros Pereira
This study aimed to compare religiosity and religious coping (RC) between Brazilian and Dutch patients with chronic obstructive pulmonary disease (COPD) and to examine associations with physical and psychological health. Religiosity, RC, and physical and psychological health were cross-sectionally assessed in 161 patients with COPD (74 from Brazil and 87 from the Netherlands). Brazilian participants showed the greatest religiosity (p < 0.05), and weak correlations were observed between religiosity/RC and exercise capacity and quality of life (p < 0...
July 21, 2021: Journal of Religion and Health
Li-Peng Yao, Ran Tao
During recent decades, the elevation of workers' health has become the utmost point of concern since it is considered among the primary indicators of economies. The economies, especially the emerging ones, are primarily focusing on every indicator to uplift their businesses. Along with the other aspects, it is also required to assess the impact of Chronic Obstructive Pulmonary Disease (COPD) on workers' health conditions in small- and medium-scale enterprises (SMEs). With this aim, we are presenting a detailed analysis to reveal useful insights regarding the COPD-workers' health nexus...
2021: Frontiers in Public Health
Seyed Ali Javad Mousavi, Jafar Aslani, Zahra Aslani, Hanieh Raji
Background: Impulse oscillometry (IOS) is a method that does not depend on the cooperation of the patient and can detect small airway diseases with higher sensitivity than spirometry. However, the clinical application value of IOS in the screening of patients exposed to risk factors COPD and early diagnosis remains unclear. The aim of this study is to evaluate diagnostic sensitivity of IOS in the early detection of patients exposed to risk factors COPD. Methods: A prospective cross-sectional study was conducted in Rasoul Akram Hospital, Tehran, Iran, from 2013 to 2015...
2021: Medical Journal of the Islamic Republic of Iran
Stefanie Krick, E Scott Helton, Molly Easter, Seth Bollenbecker, Rebecca Denson, Rennan Zaharias, Phillip Cochran, Shia Vang, Elex Harris, James M Wells, Jarrod W Barnes
Chronic obstructive pulmonary disease (COPD) is a systemic disease strongly associated with cigarette smoking, airway inflammation, and acute disease exacerbations. Changes in terminal sialylation and fucosylation of asparagine (N)-linked glycans have been documented in COPD, but the role that glycosyltransferases may play in the regulation of N-linked glycans in COPD has not been fully elucidated. Recent studies suggest that modulation of ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase-1), which catalyzes terminal α2-6 sialylation of cellular proteins, may regulate inflammation and contribute to COPD phenotype(s)...
2021: Frontiers in Immunology
Haiyan Ge, Xuanqi Liu, Wenchao Gu, Xiumin Feng, Fengying Zhang, Fengfeng Han, Yechang Qian, Xiaoyan Jin, Beilan Gao, Li Yu, Hong Bao, Min Zhou, Shengqing Li, Zhijun Jie, Jian Wang, Zhihong Chen, Jingqing Hang, Jingxi Zhang, Huili Zhu
Background: Chronic obstructive pulmonary disease (COPD) often coexists with multiple comorbidities which may have a significant impact on acute exacerbations of patients. At present, what kind of comorbidities affects acute exacerbations and how comorbidities lead to poor prognosis are still controversial. The purpose of our study is to determine the impact of comorbidities on COPD exacerbation and establish an acute exacerbation risk assessment system related to comorbidities. Methods: A total of 742 COPD patients participated in the Shanghai COPD Investigation on Comorbidity Program (SCICP, ChiCTR2000030911)...
2021: Journal of Inflammation Research
Joanne Sloots, Mirthe Bakker, Job van der Palen, Michiel Eijsvogel, Paul van der Valk, Gerard Linssen, Clara van Ommeren, Martijn Grinovero, Monique Tabak, Tanja Effing, Anke Lenferink
Background: Chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) often coexist and share periods of symptom deterioration. Electronic health (eHealth) might play an important role in adherence to interventions for the self-management of COPD and CHF symptoms by facilitating and supporting home-based care. Methods: In this pilot study, an eHealth self-management intervention was developed based on paper versions of multi-morbid exacerbation action plans and evaluated in patients with both COPD and CHF...
2021: International Journal of Chronic Obstructive Pulmonary Disease
Yongmei Zhang, Xiaoxuan Meng, Yuehao Shen, Jiajia Xie, Xi Yu, Qiaoshuo Wang, Lan Wang
Purpose: To analyze the reliability and validity of the Brief international classification of functioning, disability and health (ICF) core set for chronic obstructive pulmonary disease (COPD). Patients and Methods: A cross-sectional study was conducted in four tertiary hospitals in Tianjin, China. A total of 100 patients with COPD were selected to evaluate functioning and disability involving body functions, body structures, activities and participation as well as environmental factors of the Brief ICF core set for COPD...
2021: International Journal of Chronic Obstructive Pulmonary Disease
Yong Jun Choi, Do Sun Kwon, Taehee Kim, Jae Hwa Cho, Hyung Jung Kim, Min Kwang Byun, Hye Jung Park
Alanine aminotransferase (ALT) levels reflect skeletal muscle volume and general performance, which are associated with chronic obstructive pulmonary disease (COPD) development and prognosis. This study aimed to investigate ALT levels as a risk factor for COPD development. This 13-year population-based retrospective observational cohort study included 422,452 participants for analysis. We classified groups according to the baseline ALT levels (groups 1-5: ALT (IU/L) < 10; 10-19; 20-29; 30-39; and ≥ 40, respectively)...
July 21, 2021: Scientific Reports
James D Chalmers, Jakko van Ingen, Roald van der Laan, Jean-Louis Herrmann
Nontuberculous mycobacterial (NTM) pulmonary disease is a chronic respiratory infection associated with declining lung function, radiological deterioration and significantly increased morbidity and mortality. Patients often have underlying lung conditions, particularly bronchiectasis and COPD. NTM pulmonary disease is difficult to treat because mycobacteria can evade host defences and antimicrobial therapy through extracellular persistence in biofilms and sequestration into macrophages. Management of NTM pulmonary disease remains challenging and outcomes are often poor, partly due to limited penetration of antibiotics into intracellular spaces and biofilms...
September 30, 2021: European Respiratory Review: An Official Journal of the European Respiratory Society
Tara Ballav Adhikari, Dinesh Neupane, Arjun Karki, Arne Drews, Brendan Cooper, Marieann Högman, Torben Sigsgaard, Per Kallestrup
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide and the commonest of non-communicable diseases (NCDs) in Nepal. Risk factors like indoor and outdoor air pollution, a high prevalence of smoking, and the lack of awareness of COPD make it a serious public health concern. However, no attempt has been made in Nepal to estimate its burden and address the disease at the community level. METHOD: This study aims to evaluate the effect of a community-based health educational intervention administered by Female Community Health Volunteers (FCHVs) on the prevention and management of COPD...
July 21, 2021: Trials
Stefan Paciocco, Anita Kothari, Christopher J Licskai, Madonna Ferrone, Shannon L Sibbald
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a prevalent chronic disease that requires comprehensive approaches to manage; it accounts for a significant portion of Canada's annual healthcare spending. Interprofessional teams are effective at providing chronic disease management that meets the needs of patients. As part of an ongoing initiative, a COPD management program, the Best Care COPD program was implemented in a primary care setting. The objectives of this research were to determine site-specific factors facilitating or impeding the implementation of a COPD program in a new setting, while evaluating the implementation strategy used...
July 21, 2021: BMC Health Services Research
Chi-Tai Lee, Ping-Huai Wang
BACKGROUND: Low handgrip strength (HGS) is independently associated with a higher exacerbation risk in stable chronic obstructive pulmonary disease (COPD); however, the relationship between HGS while being admitted for COPD exacerbation and further exacerbation risk after discharge remains unclear. METHODS: We enrolled patients admitted for COPD exacerbation between January 2018 and June 2019. HGS tests were done within 3 days after admission. The primary endpoint was exacerbations within 12 months after the index admission, which needed emergency room visits or hospital admission...
July 21, 2021: BMC Pulmonary Medicine
Lianne Parkin, Sheila Williams, Katrina Sharples, David Barson, Simon Horsburgh, Rod Jackson, Billy Wu, Jack Dummer
BACKGROUND: Coronary heart disease occurs more frequently among patients with chronic obstructive pulmonary disease (COPD) compared to those without COPD. While some research suggests that long-acting bronchodilators might confer an additional risk of acute coronary syndrome (ACS), information from real-world clinical practice about the cardiovascular impact of using two versus one long-acting bronchodilator for COPD is limited. We undertook a population-based nested case-control study to estimate the risk of ACS in users of both a long-acting muscarinic antagonist (LAMA) and a long-acting beta2-agonist (LABA) relative to users of a LAMA...
July 21, 2021: Journal of Internal Medicine
Xian-Feng Meng, Qing-Yan Lin, Honglei Yin, Zeng-Qi Li
BACKGROUND: This study evaluates role of hyperpolarized 3 helium (3 He) MRI measured apparent diffusion coefficient (ADC) in examining pulmonary function of chronic obstructive pulmonary disease (COPD) patients. METHODS: After literature search in electronic databases, studies were selected by following precise eligibility criteria. Meta-analyses were performed to estimate mean difference in ADC between COPD patients and healthy individuals, and to seek correlations between lung ADC and pulmonary function...
July 19, 2021: Clinical Respiratory Journal
Koichi Nishimura, Toru Oga, Kazuhito Nakayasu, Hiroyuki Taniguchi, Tomoya Ogawa, Fumiko Watanabe, Shinichi Arizono, Masaaki Kusunose, Ryo Sanda, Ayumi Shibayama, Sawako Okamoto, Janelle Yorke
INTRODUCTION: The Dyspnoea-12 (D-12) is a brief, easy to complete questionnaire for measuring breathlessness. OBJECTIVES: To facilitate further efforts to measure dyspnoea in real clinical settings, the authors aimed to develop and validate a Japanese version of the D-12 and also compare the D-12 with the Baseline Dyspnea Index (BDI) and the Activity component of the St. George's Respiratory Questionnaire (SGRQ). METHODS: The standardized procedure in accordance with international guidelines was used to create the translation...
July 19, 2021: Clinical Respiratory Journal
Yixiao Zhao, Andrew M Hernandez, John M Boone, Sabee Molloi
PURPOSE: Small airways with inner diameters less than 2 mm are sites of major airflow limitations in patients with chronic obstructive pulmonary disease (COPD) and asthma. The purpose of this study is to investigate the limitations for accurate assessment of small airway dimensions using both high-resolution CT (HRCT) and conventional normal-resolution CT at low dose levels. METHODS: To model the normal human airways from the 3rd to 20th generations, a cylindrical polyurethane phantom with 14 airway tubes of inner diameters (ID) ranging from 0...
July 20, 2021: Medical Physics
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