Paige Taylor, Shannon Hartzell, Alfredo Mirandola, Mario Ciocca, Giuseppe Magro, Paola Alvarez, Christine B Peterson, Christopher R Peeler, Eugene J Koay, Rebecca M Howell, Stephen F Kry
This study characterized OSLD nanoDots for use in a therapeutic carbon beam using the IROC framework for remote output verification. 
Approach: The absorbed dose correction factors for OSLD (fading, linearity, beam quality, angularity, and depletion), as defined by AAPM TG 191, were characterized for carbon beams. For the various correction factors, the effect of carbon LET was examined by characterizing in both a low and high LET setting. 
Main Results: Fading was not statistically different between reference photons and carbon, nor between low and high LET carbon; thus, the standard IROC-defined exponential function could be used to characterize fading...
April 25, 2024: Physics in Medicine and Biology