Stock and flow

BACKGROUND: Intracranial stents and flow diverters contain significant amounts of metals, notably nickel, which can cause allergic reactions in a considerable portion of the population. These allergic responses may lead to complications like in-stent stenosis (ISS) and TIA/Stroke in patients receiving stents or flow diverters for intracranial aneurysms. METHODS: We conducted a systematic review of studies from inception until July 2023, which reported outcomes of patients with metal allergy undergoing neurovascular stenting...

In light of the profound advancements in information and communication technologies ushering in the knowledge economy, the urban space is undergoing a transformation from the traditional "space of places" to the emerging "space of flows." This shift poses questions about the influence of knowledge flows on urban economic centrality. This paper seeks to address this knowledge gap by introducing a theoretical framework that elucidates how knowledge contributes to urban economic centrality. Our analysis focuses on both intra-city knowledge stocks and inter-city knowledge flows...

Skeletal muscle is the largest organ system in the human body and plays critical roles in athletic performance, mobility, and disease pathogenesis. Despite growing recognition of its importance by major health organizations, significant knowledge gaps remain regarding skeletal muscle health and its crosstalk with nearly every physiological system. Relevant public health challenges like pain, injury, obesity, and sarcopenia underscore the need to accurately assess skeletal muscle health and function. Feasible, non-invasive techniques that reliably evaluate metrics including muscle pain, dynamic structure, contractility, circulatory function, body composition, and emerging biomarkers are imperative to unraveling the complexities of skeletal muscle...

Real-world complex systems such as the earth's climate, ecosystems, stock markets, and combustion engines are prone to dynamical transitions from one state to another, with catastrophic consequences. State variables of such systems often exhibit aperiodic fluctuations, either chaotic or stochastic in nature. Often, the parameters describing a system vary with time, showing time dependency. Constrained by these effects, it becomes difficult to be warned of an impending critical transition, as such effects contaminate the precursory signals of the transition...

Global resource extraction raises concerns about environmental pressures and the security of mineral supply. Strategies to address these concerns depend on robust information on natural resource endowments, and on suitable methods to monitor and model their changes over time. However, current mineral resources and reserves reporting and accounting workflows are poorly suited for addressing mineral depletion or answering questions about the long-term sustainable supply. Our integrative review finds that the lack of a robust theoretical concept and framework for mass-balance (MB)-consistent geological stock accounting hinders systematic industry-government data integration, resource governance, and strategy development...

This study focuses on the rescheduling problem with disruptions that cause partial blockages in the urban rail transit (URT), contributing to extending the relative train rescheduling studies. The alternative driving measure (ADM), which could be regarded as one train rerouting measure, is used to skip the blocked section, and a mixed-integer nonlinear programming (MINLP) model is built based on it. Time-varying passenger flow as well as the turnaround process of rolling stocks is taken into consideration. To solve the model, a customized genetic algorithm is used to quickly generate high-quality solutions...

We evaluated the performance of 12 lateral flow devices (LFDs) by assessing their analytical sensitivity for SARS-Cov-2 variant BA.2.86. Kits from ACON, Orient Gene, Xiamen Biotime, Getein and SureScreen detected variant BA.2.86 to sufficient sensitivity levels, comparable to those observed with previous Omicron variants. The stocks of LFDs currently held by the UK government do not currently need changing for deployment for this variant.

The patterning of excitatory cortical neurons from human pluripotent stem cells (hPSCs) is a desired technique for the study of neurodevelopmental disorders, as neurons can be created and compared from control hPSC lines, hPSC lines generated from patients, and CRISPR-modified hPSC lines. Therefore, this technique allows for the examination of disease phenotypes and assists in the development of potential new therapeutics for neurodevelopmental disorders. Many protocols, however, are optimized for use with specific hPSC lines or within a single laboratory, and they often provide insufficient guidance on how to identify positive stages in the differentiation or how to troubleshoot...

The ecosystem of Bandon Bay, in the Gulf of Thailand (GoT), has been impacted since 2007 by the continued stocking of larval blue swimming crab Portunus pelagicus , also called a crab bank. In this study, the food web in the Bay was modelled using Ecopath software to compare the trophic status, interaction and energy flow among the components in the system in 2007 and 2016 (i.e., before and 10 years after the crab bank intervention). The models were based on data collected from trawling. Twenty fish and shellfish components were used in the 2007 model, while 22 were used in the 2016 model...

Climate change is expected to increase the number of heat wave events, leading to prolonged exposures to severe heat stress (HS) and the corresponding adverse effects on dairy cattle productivity. Modelling dairy cattle productivity under HS conditions is complicated because it requires comprehending the complexity, non-linearity, dynamicity, and delays in animal response. In this paper, we applied the System Dynamics methodology to understand the dynamics of animal response and system delays of observed milk yield (MY) in dairy cows under HS...

Rare-earth-doped nanoscaled BaGdF5 is known as an efficient contrasting agent for X-ray micro-CT and NMR as well as a promising candidate for X-ray photodynamic therapy, thereby opening an opportunity for theragnostic applications. Conventional synthesis of Ln-doped BaGdF5 consider a long-lasting batch procedure, while a conjugation with photosensitizer usually implies a separate stage requiring active mixing. To the best of our knowledge, in this work, we for the first time obtain BaGdF5 :Tb3+ nanophosphors in a microfluidic route at temperatures as low as 100 °C while decreasing the time of thermal treatment down to 6 min...

A 16-week feeding trial was done to examine the impacts of continuous feeding (CF) or pulse-feeding (PF) of multi-strain probiotics on Asian seabass (Lates calcarifer, 30.0 ± 0.1 g) juveniles. In this study, three different multi-strain probiotic mixtures were added to a basal diet, including (I) a mixture of different strains of Lactobacillus plantarum, (II) a mixture of the first probiotic (I) + L. delbrueckii sub bulgaricus, L. rhamnosus and L. acidophilus, and (III) a mixture of the second probiotic (II) + two quorum quenching (QQ) bacteria (Bacillus thuringiensis QQ1 and B...

Implementing green credit is a crucial step for nations looking to control social capital flows, improve environmental governance, and foster high-quality economic development in the context of the global low-carbon transition. This study analyzes the effects of green credit policy on high-quality economic development (HQED) from the perspective of enterprise innovation using panel data from 30 Chinese provinces. The data is from the period between 2011 and 2020. We use the benchmark regression and mediation effect models to analyze the relationship between green credit and HQED...

The rapidly increasing scientific research on the stock market and the visible impact of media on equity prices are nowadays in limelight. To a greater extent, causal analysis can reckon the sentimental effect of the broadcasted content on stock valuation. We propose a four stage model to detect the direction of information flow between the news sentiment and stock price. Whilst web scraping explores and extracts the news datasets, the modified VADER algorithm finds the sentiments of the aired media. The associational causal analysis determines the cause effect between the news and stock price...

Terrestrialecosystems are significant carbon sinks and are crucial for understanding the regional and global carbon cycles, energy flow, and climate change. As land use change is a significant process affecting ecosystem carbon stocks and striving for land degradation neutrality (LDN), studying it is essential for comprehending the evolution of regional carbon sink functions and achieving sustainable development goals. The drastically diverse land use patterns in each of the study area's regions resulted in significant differences in carbon stock...

Land use change, anthropogenic exploitation and climate change have impacted the flow of services in the Himalayan region. The dominant land uses in the region include natural forest, degraded forest, rubber (Hevea brasiliensis) plantations, Areca catechu plantations, Areca agroforestry and Piper agroforestry were considered for the study. A progressive shift in land use was defined as the conversion and restoration of a less productive system like degraded land to plantations or agroforestry systems. A land use shift was considered retrogressive when it entails the establishment of plantations after clearing natural forests or anthropogenic disturbance of natural forests resulting in forest degradation...

BACKGROUND: Compression stockings are routinely prescribed after total knee arthroplasty (TKA). Non-compressive sleeves embedded with semiconductor elements (Incrediwear) are designed to enhance blood flow. The objective of this investigation is to compare compression stockings and Incrediwear on post-TKA measures. METHODS: In this single-center prospective clinical pilot study, patients undergoing TKA were assigned to either the compression stocking (control) or Incrediwear (experimental) group...

OBJECTIVE: The use of medical compression stockings (MCS) in patients with peripheral arterial disease (PAD) and diabetes is the subject of an ongoing critical debate. While reducing leg edema of various origins by improving venous back flow, there is a concern about additional arterial flow obstruction when compression therapy is applied in pre-existing PAD. The aim of this study is to obtain further information on the use of class I MCS in patients with advanced PAD and to evaluate the framework conditions for a safe application...

In financial markets, the market-order sign exhibits strong persistence, widely known as the long-range correlation (LRC) of order flow; specifically, the sign autocorrelation function (ACF) displays long memory with power-law exponent γ, such that C(τ)∝τ^{-γ} for large time-lag τ. One of the most promising microscopic hypotheses is the order-splitting behavior at the level of individual traders. Indeed, Lillo, Mike, and Farmer (LMF) introduced in 2005 a simple microscopic model of order-splitting behavior, which predicts that the macroscopic sign correlation is quantitatively associated with the microscopic distribution of metaorders...

The annual goatgrass, Aegilops biuncialis is a rich source of genes with considerable agronomic value. This genetic potential can be exploited for wheat improvement through interspecific hybridization to increase stress resistance, grain quality and adaptability. However, the low throughput of cytogenetic selection hampers the development of alien introgressions. Using the sequence of flow-sorted chromosomes of diploid progenitors, the present study enabled the development of chromosome-specific markers. In total, 482 PCR markers were validated on wheat (Mv9kr1) and Ae...