Lisheng Ge, Neil T Hoa, Zechariah Wilson, Gabriel Arismendi-Morillo, Xiao-Tang Kong, Rajeev B Tajhya, Christine Beeton, Martin R Jadus
The Big Potassium (BK) ion channel is commonly known by a variety of names (Maxi-K, KCNMA1, slo, stretch-activated potassium channel, KCa1.1). Each name reflects a different physical property displayed by this single ion channel. This transmembrane channel is found on nearly every cell type of the body and has its own distinctive roles for that tissue type. The BKα channel contains the pore that releases potassium ions from intracellular stores. This ion channel is found on the cell membrane, endoplasmic reticulum, Golgi and mitochondria...
October 2014: International Immunopharmacology