Lore Vanderbeke, Cato Jacobs, Simon Feys, Agustin Reséndiz-Sharpe, Yves Debaveye, Greet Hermans, Stephanie Humblet-Baron, Katrien Lagrou, Philippe Meersseman, Marijke Peetermans, Laura Seldeslachts, Arno Vanstapel, Greetje Vande Velde, Eric Van Wijngaerden, Alexander Wilmer, Erik Verbeken, Gert De Hertogh, Joost Wauters
Rationale: Invasive pulmonary aspergillosis has emerged as a frequent coinfection in severe coronavirus disease (COVID-19), similarly to influenza, yet the clinical invasiveness is more debated. Objectives: We investigated the invasive nature of pulmonary aspergillosis in histology specimens of influenza and COVID-19 ICU fatalities in a tertiary care center. Methods: In this monocentric, descriptive, retrospective case series, we included adult ICU patients with PCR-proven influenza/COVID-19 respiratory failure who underwent postmortem examination and/or tracheobronchial biopsy during ICU admission from September 2009 until June 2021...
August 1, 2023: American Journal of Respiratory and Critical Care Medicine