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JOURNAL ARTICLE
Zenon Pogorelić, Boris Milovac, Tin Čohadžić, Jakov Todorić
BACKGROUND: This study aims to compare outcomes of treatment, in terms of early and late complications, between the Snodgrass and meatal mobilization (MEMO) techniques in children operated on because of distal hypospadias. METHODS: The medical records of 127 children who underwent glandular, coronal, or subcoronal hypospadias repair between 1 January 2019 and 31 December 2023 were retrospectively reviewed. A total of 105 children met the inclusion criteria and were included in further analysis...
April 9, 2024: Biomedicines
#2
JOURNAL ARTICLE
Ryan Snodgrass, Vincent Kotsubo, Scott Backhaus, Joel Ullom
Pulse tube refrigerators are a critical enabling technology for many disciplines that require low temperatures. These refrigerators dominate the total power consumption of most modern cryostats, including those that reach millikelvin temperatures using additional cooling stages. In state-of-the-art commercial pulse tube refrigerators, the acoustic coupling between the driving compressor and the refrigerator is fixed and optimized for operation at base temperature. We show that this optimization is incorrect during the cooldown process, which results in wasted power consumption by the compressor and slow cooldown speed...
April 23, 2024: Nature Communications
#3
RANDOMIZED CONTROLLED TRIAL
Sonia Ben Khalifa, Ahmed Ben Slimene, Hajer Blaiti, Refka Kaddour, Amjed Fekih Hassen, Pierre Pardessus, Christopher Brasher, Souhayl Dahmani
INTRODUCTION: Evidence regarding the potentiating effects of intravenous dexamethasone on peripheral regional anesthesia in children is sparse. The objective of the current study was to investigate the potentiating effect of intravenous dexamethasone upon pudendal block during surgical correction of hypospadias using Snodgrass technique. METHODS: The study consisted of a monocentric, randomized controlled, double-blinded study. Patients were randomized to receive either intravenous dexamethasone 0...
April 16, 2024: BMC Anesthesiology
#4
JOURNAL ARTICLE
Rajendran Ramaswamy, Samir Morsi Hegab, Hany Fawsy, Saif Saeed Ghalib, Mohamed Shawky, Ghazi Mukattash
AIMS: The aim of the study was to perform a detailed analysis of the clinical characteristics of megameatus with intact prepuce (MIP) and to audit our results of reconstructive surgeries on MIP. MATERIALS AND METHODS: Design: Retrospective analysis. Setting: Pediatric surgery department of tertiary level. Subjects, methods: Hospital records and pictures of MIP operated over a 9-year period. Age, size of penis, circumcised or not, shape of glans, external urethral meatus (EUM), urethral plate (UP), chordee, distal urethra, reconstructive surgery, and complications were analyzed...
2024: Journal of Indian Association of Pediatric Surgeons
#5
JOURNAL ARTICLE
Yvonne Benatzy, Megan A Palmer, Dieter Lütjohann, Rei-Ichi Ohno, Nadja Kampschulte, Nils Helge Schebb, Dominik C Fuhrmann, Ryan G Snodgrass, Bernhard Brüne
Macrophage cholesterol homeostasis is crucial for health and disease and has been linked to the lipid-peroxidizing enzyme arachidonate 15-lipoxygenase type B (ALOX15B), albeit molecular mechanisms remain obscure. We performed global transcriptome and immunofluorescence analysis in ALOX15B-silenced primary human macrophages and observed a reduction of nuclear sterol regulatory element-binding protein (SREBP) 2, the master transcription factor of cellular cholesterol biosynthesis. Consequently, SREBP2-target gene expression was reduced as were the sterol biosynthetic intermediates desmosterol and lathosterol as well as 25- and 27-hydroxycholesterol...
April 3, 2024: Redox Biology
#6
JOURNAL ARTICLE
Deanna M Green, Thomas Lahiri, Karen S Raraigh, Fadel Ruiz, Jacquelyn Spano, Nicholas Antos, Lynn Bonitz, Lillian Christon, Myrtha Gregoire-Bottex, Jaime E Hale, Elinor Langfelder-Schwind, Álvaro La Parra Perez, Karen Maguiness, John Massie, Erin McElroy-Barker, Meghan E McGarry, Angelique Mercier, Anne Munck, Kathryn E Oliver, Staci Self, Kathryn Singh, Michael Smiley, Steven Snodgrass, Audrey Tluczek, Pamela Tuley, Paula Lomas, Elise Wong, Sarah E Hempstead, Albert Faro, Clement L Ren
A multidisciplinary committee developed evidence-based guidelines for the management of cystic fibrosis transmembrane conductance regulator-related metabolic syndrome/cystic fibrosis screen-positive, inconclusive diagnosis (CRMS/CFSPID). A total of 24 patient, intervention, comparison, and outcome questions were generated based on surveys sent to people with CRMS/CFSPID and clinicians caring for these individuals, previous recommendations, and expert committee input. Four a priori working groups (genetic testing, monitoring, treatment, and psychosocial/communication issues) were used to provide structure to the committee...
April 5, 2024: Pediatrics
#7
JOURNAL ARTICLE
Lee T Gettler, Jelena Jankovic-Rankovic, Rieti G Gengo, Geeta N Eick, Marcela Pfaff Nash, Ewoton Newton Arumah, Adan Mohammed Boru, Said Ahmed Ali, Samuel S Urlacher, Jerrold S Meyer, J Josh Snodgrass, Rahul C Oka
When armed conflict compels people to flee from their homelands, they embark on protracted journeys during which they experience wide ranging physical, social, and psychological challenges. Few studies have focused on refugee psychosocial and physiological profiles during the transitional phase of forced migration that often involves temporary sheltering. Transient refugees' experiences can vary substantially based on local socio-ecological conditions in temporary settlements, including the length of stay, living conditions, as well as the availability and accessibility of physical and social resources...
March 12, 2024: Psychoneuroendocrinology
#8
JOURNAL ARTICLE
Melissa A Liebert, Samuel S Urlacher, Felicia C Madimenos, Theresa E Gildner, Tara J Cepon-Robins, Christopher J Harrington, Richard G Bribiescas, Lawrence S Sugiyama, J Josh Snodgrass
OBJECTIVES: The hypothalamic-pituitary-adrenal (HPA) axis and its primary end product, the glucocorticoid cortisol, are major components of the evolved human stress response. However, most studies have examined these systems among populations in high-income settings, which differ from the high pathogen and limited resource contexts in which the HPA axis functioned for most of human evolution. METHODS: We investigated variability in diurnal salivary cortisol patterns among 298 Indigenous Shuar from Amazonian Ecuador (147 males, 151 females; age 2-86 years), focusing on the effects of age, biological sex, and body mass index (BMI) in shaping differences in diurnal cortisol production...
March 22, 2024: American Journal of Human Biology: the Official Journal of the Human Biology Council
#9
JOURNAL ARTICLE
Jessica L Williams, Jamie L Perry, Taylor D Snodgrass, Davinder J Singh, M'hamed Temkit, Thomas J Sitzman
OBJECTIVE: To investigate whether flexible nasopharyngoscopy, when performed in addition to magnetic resonance imaging (MRI), influences the type of surgery selected or success of surgery in patients with velopharyngeal insufficiency (VPI). DESIGN: Cohort study. SETTING: A metropolitan children's hospital. PATIENTS: Patients with non-syndromic, repaired cleft palate presenting for management of VPI. INTERVENTIONS: MRI and nasopharyngoscopy or MRI alone for preoperative imaging of the velopharyngeal mechanism...
March 15, 2024: Cleft Palate-craniofacial Journal
#10
JOURNAL ARTICLE
T Zhang, S Peng, C-K Mao, W-W Zhu, Q-F Deng, Y-S Cao
OBJECTIVE: We aimed to explore the effectiveness of the modified tubularized incised plate urethroplasty (Snodgrass Technique) in hypospadias surgery. PATIENTS AND METHODS: A study was conducted on 50 pediatric patients with hypospadias treated in our hospital from May 2020 to May 2023. The patients were divided into two groups based on the condition of their urethral plate; 22 patients were included in the study group and 28 patients were included in the control group...
February 2024: European Review for Medical and Pharmacological Sciences
#11
JOURNAL ARTICLE
Alberto Navarro
No abstract text is available yet for this article.
March 4, 2024: Culture, Medicine and Psychiatry
#12
JOURNAL ARTICLE
Jonathan Aichner, Martin Kaefer, Sabine Zundel, Tobias Jhala, Philipp Szavay
INTRODUCTION: Teaching methods in hypospadias repair are still traditional. Available simulators often lack authenticity in terms of haptic feedback and realistic tissue handling. OBJECTIVE: Our aim was to develop a high-fidelity, easily reproducible, and affordable animal tissue model for the advanced surgical simulation of hypospadias repair with realistic haptic feedback and tissue handling. MATERIAL AND METHODS: A regular-sized chicken leg and a lamb tenderloin are used to assess the feasibility of simulating hypospadias correction by using the example of a Snodgrass Tubularized Incised Plate-Repair...
February 17, 2024: Journal of Pediatric Urology
#13
JOURNAL ARTICLE
Kate F Higdon, Ian Neath, Aimee M Surprenant, Tyler M Ensor
The picture-superiority effect is the finding that memory for pictures exceeds memory for words on many tasks. According to dual-coding theory (Paivio, 1971), the pictures' mnemonic advantage stems from their greater likelihood to be labelled relative to words being imaged. In contrast, distinctiveness accounts (Mintzer & Snodgrass, 1999) hold that the greater variability of pictures compared to words leads to their mnemonic advantage. Ensor, Surprenant, et al. (2019) tested these accounts in old/new and forced-choice recognition by increasing the physical distinctiveness of words and decreasing the physical distinctiveness of pictures...
February 15, 2024: Quarterly Journal of Experimental Psychology: QJEP
#14
JOURNAL ARTICLE
Jamie Adams, Susan M Sherman, Helen L Williams
Over the last 40 years, object recognition studies have moved from using simple line drawings, to more detailed illustrations, to more ecologically valid photographic representations. Researchers now have access to various stimuli sets, however, existing sets lack the ability to independently manipulate item format, as the concepts depicted are unique to the set they derive from. To enable such comparisons, Rossion and Pourtois (2004) revisited Snodgrass and Vanderwart's (1980) line drawings and digitally re-drew the objects, adding texture and shading...
February 8, 2024: Behavior Research Methods
#15
REVIEW
Geraint H Jones, Colin Snodgrass, Cecilia Tubiana, Michael Küppers, Hideyo Kawakita, Luisa M Lara, Jessica Agarwal, Nicolas André, Nicholas Attree, Uli Auster, Stefano Bagnulo, Michele Bannister, Arnaud Beth, Neil Bowles, Andrew Coates, Luigi Colangeli, Carlos Corral van Damme, Vania Da Deppo, Johan De Keyser, Vincenzo Della Corte, Niklas Edberg, Mohamed Ramy El-Maarry, Sara Faggi, Marco Fulle, Ryu Funase, Marina Galand, Charlotte Goetz, Olivier Groussin, Aurélie Guilbert-Lepoutre, Pierre Henri, Satoshi Kasahara, Akos Kereszturi, Mark Kidger, Matthew Knight, Rosita Kokotanekova, Ivana Kolmasova, Konrad Kossacki, Ekkehard Kührt, Yuna Kwon, Fiorangela La Forgia, Anny-Chantal Levasseur-Regourd, Manuela Lippi, Andrea Longobardo, Raphael Marschall, Marek Morawski, Olga Muñoz, Antti Näsilä, Hans Nilsson, Cyrielle Opitom, Mihkel Pajusalu, Antoine Pommerol, Lubomir Prech, Nicola Rando, Francesco Ratti, Hanna Rothkaehl, Alessandra Rotundi, Martin Rubin, Naoya Sakatani, Joan Pau Sánchez, Cyril Simon Wedlund, Anamarija Stankov, Nicolas Thomas, Imre Toth, Geronimo Villanueva, Jean-Baptiste Vincent, Martin Volwerk, Peter Wurz, Arno Wielders, Kazuo Yoshioka, Konrad Aleksiejuk, Fernando Alvarez, Carine Amoros, Shahid Aslam, Barbara Atamaniuk, Jędrzej Baran, Tomasz Barciński, Thomas Beck, Thomas Behnke, Martin Berglund, Ivano Bertini, Marcin Bieda, Piotr Binczyk, Martin-Diego Busch, Andrei Cacovean, Maria Teresa Capria, Chris Carr, José María Castro Marín, Matteo Ceriotti, Paolo Chioetto, Agata Chuchra-Konrad, Lorenzo Cocola, Fabrice Colin, Chiaki Crews, Victoria Cripps, Emanuele Cupido, Alberto Dassatti, Björn J R Davidsson, Thierry De Roche, Jan Deca, Simone Del Togno, Frederik Dhooghe, Kerri Donaldson Hanna, Anders Eriksson, Andrey Fedorov, Estela Fernández-Valenzuela, Stefano Ferretti, Johan Floriot, Fabio Frassetto, Jesper Fredriksson, Philippe Garnier, Dorota Gaweł, Vincent Génot, Thomas Gerber, Karl-Heinz Glassmeier, Mikael Granvik, Benjamin Grison, Herbert Gunell, Tedjani Hachemi, Christian Hagen, Rajkumar Hajra, Yuki Harada, Johann Hasiba, Nico Haslebacher, Miguel Luis Herranz De La Revilla, Daniel Hestroffer, Tilak Hewagama, Carrie Holt, Stubbe Hviid, Iaroslav Iakubivskyi, Laura Inno, Patrick Irwin, Stavro Ivanovski, Jiri Jansky, Irmgard Jernej, Harald Jeszenszky, Jaime Jimenéz, Laurent Jorda, Mihkel Kama, Shingo Kameda, Michael S P Kelley, Kamil Klepacki, Tomáš Kohout, Hirotsugu Kojima, Tomasz Kowalski, Masaki Kuwabara, Michal Ladno, Gunter Laky, Helmut Lammer, Radek Lan, Benoit Lavraud, Monica Lazzarin, Olivier Le Duff, Qiu-Mei Lee, Cezary Lesniak, Zoe Lewis, Zhong-Yi Lin, Tim Lister, Stephen Lowry, Werner Magnes, Johannes Markkanen, Ignacio Martinez Navajas, Zita Martins, Ayako Matsuoka, Barbara Matyjasiak, Christian Mazelle, Elena Mazzotta Epifani, Mirko Meier, Harald Michaelis, Marco Micheli, Alessandra Migliorini, Aude-Lyse Millet, Fernando Moreno, Stefano Mottola, Bruno Moutounaick, Karri Muinonen, Daniel R Müller, Go Murakami, Naofumi Murata, Kamil Myszka, Shintaro Nakajima, Zoltan Nemeth, Artiom Nikolajev, Simone Nordera, Dan Ohlsson, Aire Olesk, Harald Ottacher, Naoya Ozaki, Christophe Oziol, Manish Patel, Aditya Savio Paul, Antti Penttilä, Claudio Pernechele, Joakim Peterson, Enrico Petraglio, Alice Maria Piccirillo, Ferdinand Plaschke, Szymon Polak, Frank Postberg, Herman Proosa, Silvia Protopapa, Walter Puccio, Sylvain Ranvier, Sean Raymond, Ingo Richter, Martin Rieder, Roberto Rigamonti, Irene Ruiz Rodriguez, Ondrej Santolik, Takahiro Sasaki, Rolf Schrödter, Katherine Shirley, Andris Slavinskis, Balint Sodor, Jan Soucek, Peter Stephenson, Linus Stöckli, Paweł Szewczyk, Gabor Troznai, Ludek Uhlir, Naoto Usami, Aris Valavanoglou, Jakub Vaverka, Wei Wang, Xiao-Dong Wang, Gaëtan Wattieaux, Martin Wieser, Sebastian Wolf, Hajime Yano, Ichiro Yoshikawa, Vladimir Zakharov, Tomasz Zawistowski, Paola Zuppella, Giovanna Rinaldi, Hantao Ji
Here we describe the novel, multi-point Comet Interceptor mission. It is dedicated to the exploration of a little-processed long-period comet, possibly entering the inner Solar System for the first time, or to encounter an interstellar object originating at another star. The objectives of the mission are to address the following questions: What are the surface composition, shape, morphology, and structure of the target object? What is the composition of the gas and dust in the coma, its connection to the nucleus, and the nature of its interaction with the solar wind? The mission was proposed to the European Space Agency in 2018, and formally adopted by the agency in June 2022, for launch in 2029 together with the Ariel mission...
2024: Space Science Reviews
#16
JOURNAL ARTICLE
Mohammad Daboos, Mohamed Abdelmaboud, Ahmed Azab, Mohamed Abdelaziz, Hany Eldamanhory
INTRODUCTION: The original description of tubularized incised plate urethroplasty (TIPU) was provided by Snodgrass in 1994. The results were significantly improved by several modifications. To decrease the incidence of complications, interposing a vascularized flap after tubularization of the neourethra is recommended. The extent to which the type of interposed tissue has a direct effect on the rate of complications and cosmetic outcomes after TIPU repair is considered the answer to the main hypothesis of this study...
January 23, 2024: European Journal of Pediatric Surgery
#17
JOURNAL ARTICLE
Waseema Patel, Ravi G Shankar, Mark A Smith, H Ralph Snodgrass, Munir Pirmohamed, Andrea L Jorgensen, Ana Alfirevic, David Dickens
4-Chlorokynurenine (4-Cl-KYN, AV-101) is a prodrug of a NMDA receptor antagonist and is in clinical development for potential CNS indications. We sought to further understand the distribution and metabolism of 4-Cl-KYN, as this information might provide a strategy to enhance the clinical development of this drug. We used excretion studies in rats, in vitro transporter assays, and pharmacogenetic analysis of clinical trial data to determine how 4-Cl-KYN and metabolites are distributed. Our data indicated that a novel acetylated metabolite ( N -acetyl-4-Cl-KYN) did not affect the uptake of 4-Cl-KYN across the blood-brain barrier via LAT1...
January 23, 2024: Molecular Pharmaceutics
#18
B E Morgado, B Sicardy, F Braga-Ribas, J L Ortiz, H Salo, F Vachier, J Desmars, C L Pereira, P Santos-Sanz, R Sfair, T de Santana, M Assafin, R Vieira-Martins, A R Gomes-Júnior, G Margoti, V S Dhillon, E Fernández-Valenzuela, J Broughton, J Bradshaw, R Langersek, G Benedetti-Rossi, D Souami, B J Holler, M Kretlow, R C Boufleur, J I B Camargo, R Duffard, W Beisker, N Morales, J Lecacheux, F L Rommel, D Herald, W Benz, E Jehin, F Jankowsky, T R Marsh, S P Littlefair, G Bruno, I Pagano, A Brandeker, A Collier-Cameron, H G Florén, N Hara, G Olofsson, T G Wilson, Z Benkhaldoun, R Busuttil, A Burdanov, M Ferrais, D Gault, M Gillon, W Hanna, S Kerr, U Kolb, P Nosworthy, D Sebastian, C Snodgrass, J P Teng, J de Wit
No abstract text is available yet for this article.
January 16, 2024: Nature
#19
REVIEW
Physical therapy interventions used to treat individuals with biceps tendinopathy: a scoping review.
Amy W McDevitt, Jodi L Young, Joshua A Cleland, Paisley Hiefield, Suzanne J Snodgrass
BACKGROUND: Shoulder pain related to pathology of the long head of the biceps tendon (LHBT) can be debilitating. Chronic LHBT tendinopathy is a common condition that is difficult to treat. Little consensus exists regarding the optimal approach to treating individuals with LHBT tendinopathy. OBJECTIVE: To systematically scope the literature to identify and present the available information regarding physical therapist interventions used for the management of individuals with LHBT tendinopathy including types of interventions used or recommended...
December 27, 2023: Brazilian Journal of Physical Therapy
#20
JOURNAL ARTICLE
Camrin D Braun, Alice Della Penna, Martin C Arostegui, Pedro Afonso, Michael L Berumen, Barbara A Block, Craig A Brown, Jorge Fontes, Miguel Furtado, Austin J Gallagher, Peter Gaube, Walter J Golet, Jeff Kneebone, Bruno C L Macena, Gonzalo Mucientes, Eric S Orbesen, Nuno Queiroz, Brendan D Shea, Jason Schratwieser, David W Sims, Gregory B Skomal, Derke Snodgrass, Simon R Thorrold
Many predator species make regular excursions from near-surface waters to the twilight (200 to 1,000 m) and midnight (1,000 to 3,000 m) zones of the deep pelagic ocean. While the occurrence of significant vertical movements into the deep ocean has evolved independently across taxonomic groups, the functional role(s) and ecological significance of these movements remain poorly understood. Here, we integrate results from satellite tagging efforts with model predictions of deep prey layers in the North Atlantic Ocean to determine whether prey distributions are correlated with vertical habitat use across 12 species of predators...
November 21, 2023: Proceedings of the National Academy of Sciences of the United States of America
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