Jie Wang, Hanqing Li, Yuanyuan Liu, Nicolette E Andrzejczyk, Kun Qiao, Yongfang Ma, Shengli Zhou, Wenjun Gui, Guonian Zhu, Shuying Li, Daniel Schlenk
Deltamethrin (DM) is a widely used insecticide that has demonstrated developmental toxicity in the early life stages of fish. To better characterize the underlying mechanisms, embryos from Tg(cmlc2:RFP), Tg(apo14:GFP), and Tg(mpx:GFP) transgenic strains of zebrafish were exposed to nominal DM concentrations of 0.1, 1, 10, 25, and 50 μg/L until 120 h post-fertilization (hpf). Heart size increased 56.7%, and liver size was reduced by 17.1% in zebrafish exposed to 22.7 and 24.2 μg/L DM, respectively...
April 30, 2024: Environmental Science & Technology