S S Sarycheva
The aim of this study was to estimate the effective doses (EDs) to children undergoing pediatric interventional cardiology examinations in hospitals of St.-Petersburg, to calculate associated dose conversion coefficients (DCCs) and to investigate their dependence of different parameters of the various procedures. Basic parameters of pediatric cardiology examinations and patient doses were studied in three main pediatric city hospitals. More than 300 examinations were under consideration. The technical, geometrical and dosimetric parameters, as well as patients' parameters, for each individual procedure were collected...
April 9, 2021: Radiation Protection Dosimetry
Jeremy Brownstein, Muhammad Afzal, Toshimasa Okabe, Thura T Harfi, Matthew S Tong, Evan Thomas, Geoffrey Hugo, Phillip Cuculich, Cliff Robinson, Terence Williams
PURPOSE: Cardiac radioablation (CRA) utilizing stereotactic body radiation therapy is gaining popularity as a non-invasive treatment for otherwise refractory ventricular arrhythmias. As radiation oncologists may be unaccustomed to the lexicon employed by cardiologists to describe the location of arrhythmogenic foci, a preliminary guide to cardiac-specific anatomy and orientation is needed to foster effective communication between the radiation oncologist and cardiology team. MATERIALS AND METHODS: ECG-gated and respiratory-gated CTs were acquired per institutional protocol...
April 6, 2021: International Journal of Radiation Oncology, Biology, Physics
Stuart Spencer, Rupa Sarkar
No abstract text is available yet for this article.
April 6, 2021: Lancet
Orsolya Kiss, Mate Babity, Attila Kovacs, Judit Skopal, Hajnalka Vago, Balint Karoly Lakatos, Csaba Bognar, Reka Rakoczi, Mark Zamodics, Lorinc Frivaldszky, Anna Menyhart-Hetenyi, Zsofia Dohy, Csilla Czimbalmos, Liliana Szabo, Bela Merkely
The significance of cardiology screening of referees is not well established. Cardiovascular risk factors and diseases were examined in asymptomatic Hungarian elite handball referees undergoing extended screening: personal/family history, physical examination, 12-lead ECG, laboratory tests, body-composition analysis, echocardiography, and cardiopulmonary exercise testing. Holter-ECG (n = 8), blood pressure monitorization (n = 10), cardiac magnetic resonance imaging (CMR; n = 27) and computer tomography (CCT; n = 4) were also carried out if needed...
2021: PloS One
Richard N Pierson, Wayne J Hawthorne
No abstract text is available yet for this article.
March 2021: Xenotransplantation
Shuai Yuan, Stephen Burgess, Mike Laffan, Amy M Mason, Martin Dichgans, Dipender Gill, Susanna C Larsson
Background We conducted Mendelian randomization analyses investigating the linear associations of genetically proxied inhibition of different coagulation factors with risk of common cardiovascular diseases. Methods and Results Genetic instruments proxying coagulation factor inhibition were identified from genome-wide association studies for activated partial thromboplastin time and prothrombin time in BioBank Japan (up to 58 110 participants). Instruments were identified for 9 coagulation factors (fibrinogen alpha, beta, and gamma chain; and factors II, V, VII, X, XI, and XII)...
April 9, 2021: Journal of the American Heart Association
Hui-Lin Hu, Hao Chen, Chun-Yan Zhu, Xin Yue, Hua-Wei Wang, Gang Qian, Chang-Lin Zhai, Chao-Jie He
Background Hypertrophic cardiomyopathy (HCM) is considered to be the most common cause of sudden death in young people and is associated with an elevated risk of mood disorders. Depression has emerged as a critical risk factor for development and progression of coronary artery disease; however, the association between depression and HCM outcomes is less clear. We sought to examine the impact of depression on clinical outcomes in patients with HCM. Methods and Results Between January 2014 and December 2017, 820 patients with HCM were recruited and followed for an average of 4...
April 9, 2021: Journal of the American Heart Association
Jay Ramchand, Pooja Podugu, Nancy Obuchowski, Serge C Harb, Michael Chetrit, Alex Milinovich, Brian Griffin, Louise M Burrell, W H Wilson Tang, Deborah H Kwon, Scott D Flamm
Background Left ventricular non-compaction remains a poorly described entity, which has led to challenges of overdiagnosis. We aimed to evaluate if the presence of a thin compacted myocardial layer portends poorer outcomes in individuals meeting cardiac magnetic resonance criteria for left ventricular non-compaction . Methods and Results This was an observational, retrospective cohort study involving individuals selected from the Cleveland Clinic Foundation cardiac magnetic resonance database (N=26 531). Between 2000 and 2018, 328 individuals ≥12 years, with left ventricular non-compaction or excessive trabeculations based on the cardiac magnetic resonance Petersen criteria were included...
April 9, 2021: Journal of the American Heart Association
Olatokunbo Osibogun, Oluseye Ogunmoroti, Lena Mathews, Victor Okunrintemi, Martin Tibuakuu, Erin D Michos
Background Greater acculturation is associated with increased risk of cardiovascular disease. However, little is known about the association between acculturation and ideal cardiovascular health (CVH) as measured by the American Heart Association's 7 CVH metrics. We investigated the association between acculturation and ideal CVH among a multi-ethnic cohort of US adults free of clinical cardiovascular disease at baseline. Methods and Results This was a cross-sectional analysis of 6506 men and women aged 45 to 84 years of 4 races/ethnicities...
April 9, 2021: Journal of the American Heart Association
Pedro A Lemos, Marcelo Franken, Jose Mariani, Fabio G Pitta, Fredric Ap Oliveira, Gabriella Cunha-Lima, Adriano M Caixeta, Breno O Almeida, Rodrigo G Garcia
Aim: Traditional percutaneous cardiovascular interventions require close physical proximity between the patients and the healthcare team, posing occupational hazards that range from radiation exposure to interpersonal air contamination. Materials & methods: Prospective single-arm pilot study (n = 10) to investigate robotic-assisted intervention as a strategy to reduce proximity during the procedure. Primary end point: composite of angiographic success, intervention performed with the team positioned >2 meters from the patient for ≥50% procedure duration, and absence of in-hospital death or acute target lesion occlusion...
April 9, 2021: Future Cardiology
Liam Mullen, Mohammed N Meah, Ahmed Elamin, Suneil Aggarwal, Adeel Shahzad, Matthew Shaw, Jaroslav Hasara, Muhammad Rashid, Michael Fisher, Turab Ali, Billal Patel, Wern Y Ding, Ruth Grainger, Thomas Heseltine, Bilal H Kirmani, Mohammed Obeidat, Yande Kasolo, Jecko Thatchil, Aleem Khand
Background Major bleeding after acute coronary syndrome predicts a poor outcome but is challenging to define. The choice of antiplatelet influences bleeding risk. Methods and Results Major bleeding, subsequent myocardial infarction (MI), and all-cause mortality to 1 year were compared in consecutive patients with acute coronary syndrome treated with clopidogrel (n=2491 between 2011 and 2013) and ticagrelor (n=2625 between 2012 and 2015) in 5 English hospitals. Clinical outcomes were identified from national hospital episode statistics...
April 9, 2021: Journal of the American Heart Association
Ilker Gonen, Aslan Babayigit, Helen Bornaun, Beril Yasa, Seyma Memur, Seda Yilmaz Semerci, Merih Cetinkaya
Aim: To develop a novel clinical scoring system for predicting hemodynamically significant patent ductus arteriosus (hsPDA) in extremely low birth weight (ELBW) infants. Methods: A prospective observational study was conducted among ELBW infants born in the study center during a 6-month period. Fourteen items were selected on a literature review basis and weighed by severity on an arbitrary 1-4 scale, the sum of which represented the Scoring preterm Infants for PDA cLinically without Echocardiographic evaluation (SIMPLE) score...
2021: Frontiers in Pediatrics
Jakub Nozewski, Grzegorz Grzesk, Maria Klopocka, Michal Wicinski, Klara Nicpon-Nozewska, Jakub Konieczny, Adam Wlodarczyk
Background: The current ERC guidelines are the source of many positive changes, reduction of mortality, length of hospitalization and improvement of prognosis of STEMI patients. However, there is a small group of patients whose slight modification in guidelines would further reduce in-hospital mortality and hospitalization costs. These are patients with concomitant STEMI infarction and gastrointestinal bleeding. Methods: Two separate methods of treatment were compared in patients with concomitant gastrointestinal bleeding and ST-segment elevation myocardial infarction...
2021: Vascular Health and Risk Management
Angela Pirillo, Manuela Casula, Elena Olmastroni, Giuseppe D Norata, Alberico L Catapano
Dyslipidaemias are alterations to the plasma lipid profile that are often associated with clinical conditions. Dyslipidaemias, particularly elevated plasma LDL-cholesterol levels, are major risk factors for cardiovascular disease, but some forms, such as hypertriglyceridaemia, are associated with severe diseases in other organ systems, including non-alcoholic fatty liver disease and acute pancreatitis. Dyslipidaemias can be genetically determined (primary or familial dyslipidaemias) or secondary to other conditions (such as diabetes mellitus, obesity or an unhealthy lifestyle), the latter being more common...
April 8, 2021: Nature Reviews. Cardiology
Henry J Pownall, Corina Rosales, Baiba K Gillard, Antonio M Gotto
Plasma HDL-cholesterol concentrations correlate negatively with the risk of atherosclerotic cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its atheroprotective effect through its role in reverse cholesterol transport, which comprises the efflux of cholesterol from macrophages to early forms of HDL, followed by the conversion of free cholesterol (FCh) contained in HDL into cholesteryl esters, which are hepatically extracted from the plasma by HDL receptors and transferred to the bile for intestinal excretion...
April 8, 2021: Nature Reviews. Cardiology
Clara Thomas, Martin Möckel, Julia Searle, Jörn Ole Vollert, Rajan Somasundaram, Anna Slagman
BACKGROUND AND IMPORTANCE: Differences between men and women visiting the emergency department (ED) with nonsurgical complaints have mostly been investigated in small, diagnosis-based subpopulations. OBJECTIVE: This study investigated sex-differences in an unselected cohort of nonsurgical ED patients. DESIGN: Secondary data of all patients attending two EDs of the Charité, Universitätsmedizin Berlin collected in the framework of their medical evaluation was reviewed...
April 5, 2021: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
Qinhua Jin, Juying Qian, Yujie Zhou, Jing Jing, Yizhe Wu, Yuyang Liu, Hua Shen, Jun Guo, Zhijun Sun, Yu Wang, Lian Chen, Yundai Chen
OBJECTIVE: The study sought to assess the effectiveness and safety of the novel P60 Vivolight frequency-domain optical coherence tomography (OCT) system (Shenzhen Vivolight Medical Device & Technology). METHODS: A total of 90 patients were enrolled from 3 institutions. The pullbacks were performed with both the P60 Vivolight OCT system and the Ilumien Optis OCT system (Abbott Vascular). The primary endpoint was the clear stent length (CSL). Device safety was assessed by the record of serious procedure-related or postprocedure adverse events...
April 8, 2021: Journal of Invasive Cardiology
Dilschad Murat, Christian Wilken-Tergau, Uta Gottwald, Ole Nemitz, Thomas Uher, Eberhard Schulz
OBJECTIVES: Radiation protection is essential for staff of cardiac catheterization laboratories in order to prevent long-term radiation- associated injury and disease. Instant feedback about the actual received dose may help operators to optimize the use of existing shielding devices. Therefore, the current study was designed to investigate whether routine use of real-time dosimetry may be able to reduce staff radiation exposure. METHODS AND RESULTS: Over a period of 72 days, operators and assisting nurses were equipped with RaySafe i3 real-time dosimeters (Unfors RaySafe AB), but had no access to the dosimetry results during the first half of the study...
April 5, 2021: Journal of Invasive Cardiology
Jason R Cuomo, Vishal Arora, Thad Wilkins
Despite recent advances in the assessment, risk stratification, and treatment of acute pulmonary embolism (PE), it remains a leading cause of cardiovascular morbidity and mortality in the United States each year. Patient presentation and prognosis are heterogeneous, and a variety of diagnostic and therapeutic instruments have arisen to assist in providing patients with the appropriate level of care and aggressiveness of approach. Fortunately, a growing number of institutions now have pulmonary embolism response teams (PERT) that urgently assist with risk assessment and management of patients with massive and sub-massive PE...
March 2021: Journal of the American Board of Family Medicine: JABFM
Alexis Coulourides Kogan, Kya Kraus, Bonnie Olsen, Julia I Bandini, Sangeeta C Ahluwalia
BACKGROUND: Advance care planning (ACP) is critical for older adults with heart failure; however, patient-level and clinician-level barriers exist. Although a group visit (GV) approach to engage patients in ACP has proven effective among general geriatric populations, little is known about clinician perceptions/likelihood of referral. METHODS: Qualitative study to understand clinician perspectives on GVs for ACP among older adult patients with heart failure and caregivers...
March 2021: Journal of the American Board of Family Medicine: JABFM
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