Niveditha Devasenapathy, Velayoudam Devagourou, Milind P Hote, Palleti Rajashekar, Bharathraj Kidambi, Aayush Singal, Mohsin Raj Mantoo, Manoj Soni, Gaurav Purohit, Sandeep Singh, Ganesan Karthikeyan
BACKGROUND: Left-sided mechanical prosthetic heart valve thrombosis (PVT) occurs because of suboptimal anticoagulation and is common in low-resource settings. Urgent surgery and fibrinolytic therapy (FT) are the two treatment options available for this condition. Urgent surgery is a high-risk procedure but results in successful restoration of valve function more often and is the treatment of choice in developed countries. In low-resource countries, FT is used as the default treatment strategy, though it is associated with lower success rates and a higher rate of bleeding and embolic complications...
June 14, 2024: Indian Heart Journal
Jason Schott, Olivia Allen, Zachary Rollins, Elvis Cami, Kavitha Chinnaiyan, Michael Gallagher, Timothy A Fonte, Abhay Bilolikar, Robert D Safian
Computed tomography (CTA)-derived fractional flow reserve (FFRCT ) guides the need for invasive coronary angiography (ICA). Late outcomes after FFRCT are reported in stable ischemic heart disease, but not in acute chest pain in the Emergency Department (ACP-ED). The objectives are to assess the risk of death, myocardial infarction (MI), revascularization, and ICA after FFRCT . From 2015-2018, 389 ACP-ED low-risk patients (negative biomarkers, no ECG ischemia) underwent CTA and FFRCT and were entered into a prospective institutional registry; patients were followed for 41 ± 10 months...
June 13, 2024: American Journal of Cardiology
Niyas K Naseer, Abhishek Kumar, Naeem Qureshi, C G Sajeev
OBJECTIVE: To investigate the association between three-dimensional (3-D) left ventricular ejection fraction (LVEF) and various speckle tracking echocardiographic (STE) strain parameters in non-ischemic left bundle branch block (LBBB) patients with major adverse cardiovascular events (MACE) during a one-year follow-up phase. METHOD: A total of 50 patients with non-ischemic LBBB were assessed using various parameters of 3-D echocardiography. They were compared with their same-age and sex control group and then followed up with repeat 3-D echocardiography for MACE for one year...
June 13, 2024: Indian Heart Journal
Justin Paul Gnanaraj, Vivek Jaganathan, Nilavan Asaithambi, Rajesh Sekar, Elangovan Chandrasekaran, Elavarasi Manimegalai Elangovan, Kumaran Srinivasan, Manohar Ganesan, Nageswaran Piskala Mohandoss, Pratap Kumar Gorijavaram, Rajasekar Ramesh, Ravindran Raji, Tamilselvan Kunjitham, Thiyagarjan Kaliamoorthy, Venkatesan Sangareddi, Nandakumaran Mohanan
BACKGROUND: Acute pulmonary embolism (APE) is the third most common cause of vascular death. Data on APE from India and other low-and middle-income countries is sparse. OBJECTIVES: Study the clinical characteristics, prognostic factors, in-hospital mortality (IMH) and 12 months mortality of patients with APE in India. METHODS: We prospectively enrolled 186 consecutive patients diagnosed with APE between November 2016 and November 2021 in Madras Medical College Pulmonary Embolism Registry (M-PER)...
June 13, 2024: Indian Heart Journal
Pankaj Jariwala, Gururaj Pramod Kulkarni, Arshad Punjani, Harikishan Boorugu, Dilip Gude
We evaluated empagliflozin in severe DAS patients with HF before AVR. HF patients with LVEF 30-80% and NYHA functional class II-IV symptoms got empagliflozin 10 mg or not within 6 months before AVR, along with SOC. Adding empagliflozin to the SOC before AVR reduced HF death or HHF by 73% after 6-months in a group of 20 patients (RR 0.27; p=0.022). Improving LVEF (+3.48%, p<0.001) and NT-proBNP levels (-3974.6pg/mL) with empagliflozin in SOC before AVR significantly reduced in-hospital and 6-month mortality in this patient group...
June 13, 2024: Indian Heart Journal
M Srinivasa Rao, Ajit Mullasari, Jagdish S Hiremath, G Sengottuvelu, Aparna Jaiswal, Darshan Jhala, Jitendra Singh Makkar, B C Kalmath, Bino Benjamin, Annirudha Dharmadhikari, Mihir Tanna, Aziz Khan, Siddhant Jain, K A Sambasivam, A Purnanand, N S Rama Raju, Goutam Sarkar, Hiren Prajapati, Willem J Verberk
OBJECTIVE: To evaluate paroxysmal atrial fibrillation (AF) prevalence in Indian adults who completed 24-Hour Holter monitoring. METHODS: A total of 23,847 patients (36.9% women) were analyzed for AF duration using using a software algorithm. RESULTS: AF was diagnosed in 4,153 (17.4%) patients with a median AF duration of 13 minutes and 55 seconds. CONCLUSION: AF prevalence was high and largely untreated. The short duration of AF episodes indicates a low likelihood of detection during clinical visits, highlighting its potential underestimation in Indian healthcare...
June 13, 2024: Indian Heart Journal
Matthew Hollowell, Joseph Banno, Dana Marsy, Nabin Shrestha, Jose Tan, Richard McNamara, Jeffrey Decker, Alfred Albano, Laura Franey, Wissam Abdallah, Renzo Loyaga-Rendon, Nagib Chalfoun, David Fermin
BACKGROUND: Atrial fibrillation (AF) increases stroke and mortality in patients with hypertrophic cardiomyopathy (HCM). Cardiac MRI (CMR) is increasingly used to detect late gadolinium enhancement (LGE) as a reliable indicator of left ventricular fibrosis, a potential predisposing factor of AF. Our research explored the correlation between left ventricular LGE and AF prevalence in HCM. METHODS: This retrospective study involved 351 HCM patients who underwent CMR...
June 13, 2024: International Journal of Cardiology
Shuaijun Guo, Rushani Wijesuriya, Meredith O'Connor, Margarita Moreno-Betancur, Sharon Goldfeld, David Burgner, Richard Liu, Naomi Priest
BACKGROUND: Limited evidence suggests that positive experiences in childhood may promote cardiovascular health, providing additional opportunities for prevention and early intervention. This study aimed to examine the effects of adverse and positive experiences on cardiovascular health in late childhood. METHODS: Data sources: Longitudinal Study of Australian Children (N = 1874). EXPOSURES: Adverse and positive experiences assessed repeatedly (age 0-11 years)...
June 13, 2024: International Journal of Cardiology
Tulio Caldonazo, Johannes Fischer, Alena Spagnolo, Michele Dell'Aquila, Hristo Kirov, Panagiotis Tasoudis, Ricardo E Treml, Dominique Vervoort, Michel Pompeu Sá, Torsten Doenst, Mahmoud Diab, Stefan Hagel
BACKGROUND: Complete removal of cardiac implantable electronic devices (CIEDs) is recommended in patients with CIED infections, including both systemic and localized pocket infection. The aim of the study was to provide an up-to-date and comprehensive assessment of evidence relating to the effect of complete CIED extraction in patients with a CIED infection. METHODS: We performed a systematic review and meta-analysis of studies reporting short- and mid-term outcomes in patients who had a device infection or infective endocarditis (IE) and underwent complete removal of the cardiac device (generator and leads) compared to those who received conservative therapy (no removal, partial removal, local antibiotic infiltration or isolated antibiotic therapy)...
June 13, 2024: International Journal of Cardiology
Eleana Bolla, Anne Grete Semb, Anne M Kerola, Eirik Ikdahl, Michelle Petri, Guillermo J Pons-Estel, George A Karpouzas, Petros P Sfikakis, Rosana Quintana, Durga Prasanna Misra, Eduardo Ferreira Borba, Ignacio Garcia-de la Torre, Tatiana V Popkova, Bahar Artim-Esen, Anne Troldborg, Hilda Fragoso-Loyo, Sofia Ajeganova, Ayten Yazici, Gustavo Aroca-Martinez, Haner Direskeneli, Manuel F Ugarte-Gil, Marta Mosca, Mohit Goyal, Elisabet Svenungsson, Carla Macieira, Alberta Hoi, Karoline Lerang, Nathalie Costedoat-Chalumeau, Angela Tincani, Erkin Mirrakhimov, Isabel Acosta Colman, Alvaro Danza, Loreto Massardo, Jelena Blagojevic, Neslihan Yılmaz, Dana Tegzová, Sule Yavuz, Cengiz Korkmaz, Eric Hachulla, Mario J Moreno Alvarez, Roberto Muñoz-Louis, Nikos Pantazis, Maria G Tektonidou
BACKGROUND: Systemic lupus erythematosus (SLE) is characterised by increased cardiovascular morbidity and mortality risk. We aimed to examine the prevalence of traditional cardiovascular risk factors and their control in an international survey of patients with systemic lupus erythematosus. METHODS: In this multicentre, cross-sectional study, cardiovascular risk factor data from medical files of adult patients (aged ≥18) with SLE followed between Jan 1, 2015, and Jan 1, 2020, were collected from 24 countries, across five continents...
June 10, 2024: Lancet Rheumatology
Courtney Bisson, Easha Patel, Ariel Mueller, Sunitha Suresh, Colleen Duncan, Ashish Premkumar, Sajid Shahul, Sarosh Rana
OBJECTIVE: The purpose of this study was to examine the long-term effect of a quality improvement initiative at one-year post delivery. STUDY DESIGN: This was a retrospective study of 1480 patients who delivered between October 2018 and June 2020 at the study institution and were enrolled in the Systematic Treatment and Management of PostPartum Hypertension Program (STAMPP). Patients received standardized cuffs, education, and follow-up. At the six-week postpartum follow-up, patients were again given instructions to establish follow-up...
June 14, 2024: Pregnancy Hypertension
Shih-Rong Wang, Kuan-Chih Huang, Ting-Tse Lin, Shu-Lin Chuang, Yen-Yun Yang, Jung-Chi Hsu, Cho-Kai Wu, Lian-Yu Lin
No abstract text is available yet for this article.
June 14, 2024: International Journal of Cardiology
Pasquale Pagliaro, Nina C Weber, Saveria Femminò, Giuseppe Alloatti, Claudia Penna
Despite recent progress, ischemic heart disease poses a persistent global challenge, driving significant morbidity and mortality. The pursuit of therapeutic solutions has led to the emergence of strategies such as ischemic preconditioning, postconditioning, and remote conditioning to shield the heart from myocardial ischemia/reperfusion injury (MIRI). These ischemic conditioning approaches, applied before, after, or at a distance from the affected organ, inspire future therapeutic strategies, including pharmacological conditioning...
June 15, 2024: Basic Research in Cardiology
Jussi A Hernesniemi, Teemu Pukkila, Matti Molkkari, Kjell Nikus, Leo-Pekka Lyytikäinen, Terho Lehtimäki, Jari Viik, Mika Kähönen, Esa Räsänen
BACKGROUND: Conventional measures of heart rate variability (HRV) have shown only modest associations with sudden cardiac death (SCD). Detrended fluctuation analysis (DFA), with novel methodological developments to evaluate the short-term scaling exponent, is a potentially superior method compared to conventional HRV tools. OBJECTIVES: In this study, the authors studied the analysis of the association between DFA and SCD. METHODS: The investigators studied the predictive value of ultra-short-term heart rate fluctuations (1-minute electrocardiogram samples) with DFA at rest and during different stages of physical exertion for incident SCD among 2,794 participants undergoing clinical exercise testing in the prospective FINCAVAS (Finnish Cardiovascular Study)...
May 29, 2024: JACC. Clinical Electrophysiology
Alexis Elias Malavazos, Valentina Scravaglieri, Federico Boniardi, Chiara Meregalli, Carola Dubini
No abstract text is available yet for this article.
June 15, 2024: European Journal of Preventive Cardiology
Pouya Nezafati, Andrew Ajani, Diem Dinh, Angela Brennan, David Clark, Christopher M Reid, Chin Hiew, Melanie Freeman, Dion Stub, Jaya Chandrasekhar, Anand Sharma, Ernesto Oqueli
BACKGROUND: The American College of Cardiology / American Heart Association (ACC/AHA) introduced a coronary lesion classification in 1988 to stratify coronary lesions for probability of procedural success and complications after coronary angioplasty. Our aim is to assess the validity of the ACC/AHA lesion classification in predicting outcomes of percutaneous coronary intervention (PCI) in a contemporary cohort of patients. METHODS: Consecutive PCI procedures performed between 2005 and 2018, were divided into three periods...
June 11, 2024: Cardiovascular Revascularization Medicine: Including Molecular Interventions
Ilanit Cohen, Roy Beigel, Victor Guetta, Amit Segev, Paul Fefer, Shlomo Matetzky, Israel Mazin, Michael Berger, Saritte Perlman, Israel Moshe Barbash, Tomer Ziv-Baran
BACKGROUND: Most patients after transcatheter aortic valve replacement (TAVR) are admitted directly to the cardiac intensive care unit (CICU) despite low complication rates. Reducing unnecessary CICU hospitalization reduces healthcare costs. This study aimed to compare the outcomes between patients admitted directly to the cardiology department (CD) and those admitted to CICU based on prespecified protocols. METHODS: Historical cohort study of all patients who underwent TAVR and were admitted directly to the CD according to a prespecified protocol (uncomplicated procedure, hemodynamically stable, without new conduction abnormalities) in 2017-2018, and the same number of patients meeting the same criteria who were admitted to the CICU in 2015-2016 before direct CD admission was initiated...
June 12, 2024: American Journal of the Medical Sciences
Norihisa Miyawaki, Kenichi Ishizu, Shinichi Shirai, Katsunori Miyahara, Ko Yamamoto, Tomohiro Suenaga, Akira Otani, Kenji Nakano, Tadatomo Fukushima, Euihong Ko, Yasuo Tsuru, Miho Nakamura, Toru Morofuji, Takashi Morinaga, Masaomi Hayashi, Akihiro Isotani, Nobuhisa Ohno, Shinichi Kakumoto, Kenji Ando
BACKGROUND: The semiquantitative Clinical Frailty Scale (CFS) is reportedly a useful marker for predicting short- and mid-term mortality after transcatheter aortic valve implantation (TAVI). We assessed the long-term prognostic impact of CFS in patients with severe aortic stenosis undergoing TAVI. METHODS: We prospectively assessed patients undergoing TAVI in Kokura Memorial Hospital using a 9-level CFS and enrolled 1594 patients after excluding patients with CFS 8-9...
June 12, 2024: American Heart Journal
Yui O Nozaki, Shinichiro Fujimoto, Daigo Takahashi, Ayako Kudo, Yuko O Kawaguchi, Hideyuki Sato, Hikaru Kudo, Kazuhisa Takamura, Makoto Hiki, Tomotaka Dohi, Nobuo Tomizawa, Kanako K Kumamaru, Shigeki Aoki, Tohru Minamino
BACKGROUND: On-site computed tomography-derived fractional flow reserve (CT-FFR) is a feasible method for examining lesion-specific ischemia, and plaque analysis of coronary CT angiography (CCTA) is useful for predicting future cardiac events. However, their utility and association on a per-vessel level remain unclear. METHODS: We analyzed vessels showing 50-90 % stenosis on CCTA where planned revascularization was not performed after CCTA within 90 days...
June 12, 2024: Journal of Cardiology
Reindolf Anokye, Jack Dalla Via, James Dimmock, Ben Jackson, Carl Schutz, Mie Schæffer, Joanne M Dickson, Lauren C Blekkenhorst, Mandy Stanley, Jonathan M Hodgson, Joshua R Lewis
INTRODUCTION: Cardiovascular imaging results offer valuable information that can guide health decisions, but their impact on medication use and adherence is unclear. This systematic review and meta-analysis aimed to determine the downstream impact of cardiovascular imaging results on medication use and adherence. METHODS: Searches were conducted across databases, including MEDLINE, PsychINFO, EMBASE, and relevant references up to 2024. Data were extracted from studies comparing outcomes for individuals with diseased versus normal arteries and trials comparing outcomes for individuals who were provided imaging results versus those with no access to imaging results and analysed in 2023 and 2024...
June 12, 2024: American Journal of Preventive Medicine
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