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Helicobacter Pylori primary care

Jeannine A Aminde, Guisilla A Dedino, Calypse A Ngwasiri, Kingsley S Ombaku, Cedric A Mahop Makon, Leopold Ndemnge Aminde
BACKGROUND: Almost half the world's population is infected with Helicobacter pylori (H. pylori) with the highest reported prevalence from Africa. This infection is associated with several morbid gastrointestinal conditions. Understanding the trends in seroprevalence and the factors associated with H. pylori seropositivity in dyspeptic persons can provide a guide for public health policies. METHODS: This was a retrospective study, carried out with outpatient records of Wum District Hospital (WDH) from January 2012 to December 2016...
January 8, 2019: BMC Infectious Diseases
Doron Boltin, Iris Dotan, Shlomo Birkenfeld
Background: Consensus guidelines recommend that in regions with a high rate of clarithromycin resistance, Helicobacter pylori ( H. pylori ) infection be treated with 4 drugs. Compliance with this recommendation among primary care physicians (PCPs) is low. We aimed to examine whether PCP compliance with H. pylori treatment recommendations increased following a targeted educational intervention. Methods: A questionnaire assessing H. pylori treatment was sent to >2000 PCPs in June 2015 and June 2018...
January 2019: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
Alberto Barchi, Chiara Miraglia, Alessandra Violi, Ginevra Cambiè, Antonio Nouvenne, Mario Capasso, Gioacchino Leandro, Tiziana Meschi, Gian Luigi De' Angelis, Francesco Di Mario
Upper-GI diseases are one of the most relevant issue in primary care. Nowadays they are still responsible for about 100 million ambulatory care visits only in the US. The diagnosis of almost every upper-GI condition is still deputed to invasive tests such as upper gastrointestinal endoscopy, gastroesophageal manometry or radiography. The possibility of analysing serum markers like Pepsinogens I and II, produced by gastric mucosa, in order to assess the functional characteristics of the upper GI tract has spread itself since the 80's especially in the diagnosis of peptic ulcer...
December 17, 2018: Acta Bio-medica: Atenei Parmensis
Andrzej S Tarnawski, Amrita Ahluwalia
In this editorial we comment on the article by Fukushi K et al published in the recent issue of the World Journal of Gastroenterology 2018; 24(34): 3908-3918. We focus specifically on the mechanisms of the anti-thrombotic action of aspirin, gastric mucosal injury and aging-related increased susceptibility of gastric mucosa to injury. Aspirin is widely used not only for the management of acute and chronic pain and arthritis, but also importantly for the primary and secondary prevention of cardiovascular events such as myocardial infarcts and strokes...
November 14, 2018: World Journal of Gastroenterology: WJG
Mechu Narayanan, Kavya M Reddy, Elizabeth Marsicano
Peptic ulcer disease (PUD) is a common condition that both primary care providers and gastroenterologists encounter. Symptoms of peptic ulcer disease are variable and may include abdominal pain, nausea, vomiting, weight loss and bleeding or perforation with complicated disease. Identifying the risk factors and mechanisms that lead to the development of PUD helps to understand the approach behind diagnostic and treatment strategies.
May 2018: Missouri Medicine
Renuka Malipatel, Mallikarjun Patil, Patil Pritilata Rout, Marjorie Correa, Harshad Devarbhavi
Introduction: Gastrointestinal tract (GIT) is the most common site of involvement of extranodal non-Hodgkin's lymphoma (NHL). There is regional variation in anatomical distribution of extranodal NHL, stomach being the most common site followed by small intestine. Primary gastric lymphoma (PGL) predominantly involves the antrum and corpus of the stomach. It arises from mucosa-associated lymphoid tissue (MALT) and is of B-cell lineage and often associated with Helicobacter pylori infection...
January 2018: Euroasian Journal of Hepato-Gastroenterology
F J Bosques-Padilla, J M Remes-Troche, M S González-Huezo, G Pérez-Pérez, J Torres-López, J M Abdo-Francis, M V Bielsa-Fernandez, M C Camargo, F Esquivel-Ayanegui, E Garza-González, A I Hernández-Guerrero, R Herrera-Goepfert, F M Huerta-Iga, Y Leal-Herrera, A Lopéz-Colombo, N X Ortiz-Olvera, A Riquelme-Pérez, C L Sampieri, L F Uscanga-Domínguez, J A Velarde-Ruiz Velasco
Important advances have been made since the last Mexican consensus on the diagnosis and treatment of Helicobacter pylori (H. pylori) infection was published in 2007. Therefore, the Asociación Mexicana de Gastroenterología summoned 20 experts to produce "The Fourth Mexican Consensus on Helicobacter pylori". From February to June 2017, 4 working groups were organized, a literature review was performed, and 3 voting rounds were carried out, resulting in the formulation of 32 statements for discussion and consensus...
July 2018: Revista de Gastroenterología de México
Ayse Palanduz, Levent Erdem, Birsen Durmaz Cetin, Nuran Gülgün Ozcan
BACKGROUND: Primary Helicobacter pylori (H. pylori) infection is acquired predominantly in childhood in the family setting. We aimed to investigate the presence of intrafamilial concurrent H. pylori infection. DESIGN AND SETTING: Cross-sectional analytical study with a control group, conducted in a tertiary care hospital. METHODS: Fifty adult patients with gastroduodenal symptoms who underwent gastroscopy (index parents), their spouses and their children were enrolled in the study...
May 2018: São Paulo Medical Journal, Revista Paulista de Medicina
Zekeriya Akturk, Ali Bilal Ulas, Atila Eroglu
INTRODUCTION: Zenker's diverticulum is a diverticulum of the mucosa of the pharynx, just above the cricopharyngeal muscle. It occurs commonly in elderly patients (over 70 years) and the typical symptoms include dysphagia, regurgitation, chronic cough, aspiration and weight loss. CASE: We are reporting dysphagia in a 49-years old man who was treated as having Helicobacter Pylori gastritis for three years. Being a family physician himself, the patient applied to specialists in gastroenterology, bypassing primary care...
December 2018: European Journal of General Practice
Maxwell D Mirande, Raul A Mirande
Introduction: Peptic ulcer disease has significantly decreased over the past several decades making the need for definitive surgical intervention an infrequent occurrence. Presentation of Case: A 44-year-old Caucasian female was sent to the emergency department by her primary care physician for right upper quadrant abdominal pain which had been intermittent for the past two months but acutely worsened over the last five days. During this time, she was unable to tolerate oral intake with intractable nausea and vomiting...
May 2018: Annals of Medicine and Surgery
Vincent C H Chung, Charlene H L Wong, Jessica Y L Ching, Wai Zhu Sun, Yan Li Ju, Sheung Sheung Hung, Wai Ling Lin, Ka Chun Leung, Samuel Y S Wong, Justin C Y Wu
INTRODUCTION: This trial proposes to compare the effectiveness and cost-effectiveness of electroacupuncture (EA) plus on-demand gastrocaine with waiting list for EA plus on-demand gastrocaine in providing symptom relief and quality-of-life improvement among patients with functional dyspepsia (FD). METHODS AND ANALYSIS: This is a single-centre, pragmatic, randomised parallel-group, superiority trial comparing the outcomes of (1) EA plus on-demand gastrocaine group and (2) waiting list to EA plus on-demand gastrocaine group...
March 27, 2018: BMJ Open
A P S Hungin, C R Mitchell, P Whorwell, C Mulligan, O Cole, L Agréus, P Fracasso, C Lionis, J Mendive, J-M Philippart de Foy, B Seifert, K-A Wensaas, C Winchester, N de Wit
BACKGROUND: In 2013, a systematic review and Delphi consensus reported that specific probiotics can benefit adult patients with irritable bowel syndrome (IBS) and other gastrointestinal (GI) problems. AIM: To update the consensus with new evidence. METHODS: A systematic review identified randomised, placebo-controlled trials published between January 2012 and June 2017. Evidence was graded, previously developed statements were reassessed by an 8-expert panel, and agreement was reached via Delphi consensus...
April 2018: Alimentary Pharmacology & Therapeutics
Osama Siddique, Anais Ovalle, Ayesha S Siddique, Steven F Moss
Helicobacter pylori infects approximately half the world's population and is especially prevalent in the developing world. H. pylori is an important cause of global ill health due to its known etiological role in peptic ulcer disease, dyspepsia, gastric cancer, lymphoma, and more recently, recognized in iron deficiency anemia and idiopathic thrombocytopenic purpura. Increased antibiotic usage worldwide has led to antibiotic resistance among many bacteria, including H. pylori, resulting in falling success rates of first-line anti-H...
May 2018: American Journal of Medicine
Ilva Daugule, Daiga Karklina, Silvija Remberga, Ingrida Rumba-Rozenfelde
Purpose: To analyze presence of Helicobacter pylori infection and environmental risk factors among children with and without allergy. Methods: Parents of children at primary health care centres/kindergartens and allergologist consultation were asked to answer a questionnaire and to bring a faecal sample. H. pylori infection was detected by monoclonal stool antigen test. Prevalence of H. pylori infection and risk factors were compared between individuals with and without allergy using χ2 test, ANOVA test and parameters and logistic regression...
December 2017: Pediatric Gastroenterology, Hepatology & Nutrition
Brian D Nicholson, Lucy M Abel, Philip J Turner, Christopher P Price, Carl Heneghan, Gail Hayward, Annette Plüddemann
No abstract text is available yet for this article.
December 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
Danan Gan, Aili Xu, Hongbo Du, Yong'an Ye
Objective: This aim is to evaluate the effect of Sijunzi decoction (SJZD) treating chronic atrophic gastritis (CAG). Methods: We performed searches in seven databases. The randomized controlled trials (RCTs) comparing SJZD with standard medical care or inactive intervention for CAG were enrolled. Combined therapy of SJZD plus conventional therapies compared with conventional therapies alone was also retrieved. The primary outcome included the incidence of gastric cancer and the improvement of atrophy, intestinal metaplasia, and dysplasia based on the gastroscopy and pathology...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
I Diminić-Lisica, B Bergman Marković, L Bukmir, N Bašić Marković, N Radošević Quadranti, I Lisica
Dyspepsia is a common symptom among patients in family medicine practice. The prevalence in adult population is about 40%. Two-thirds of patients have functional dyspepsia. Clinical assessment, diagnostic procedures and treatment of patients depend on the age, symptoms and Helicobacter pylori infection. In patients with dyspepsia, it is necessary to assess the potential impact of other concurrent diseases and medications that the patient regularly uses. Prompt or early endoscopy is recommended in patients with newly detected dyspepsia older than 50 and presenting with alarming symptoms...
November 2015: Acta Medica Croatica: C̆asopis Hravatske Akademije Medicinskih Znanosti
Daniela Munteanu, Ohad Etzion, Gil Ben-Yakov, Daniel Halperin, Leslie Eidelman, Doron Schwartz, Victor Novack, Naim Abufreha, Pavel Krugliak, Alexander Rozenthal, Nava Gaspar, Alexander Moshkalo, Vitaly Dizingof, Alexander Fich
BACKGROUND AND AIMS: Quadruple therapy is recommended as second-line treatment for Helicobacter pylori eradication failure. However, high cost, multiple side effects, and low adherence rates are major drawbacks to its routine use. Our aim was to compare the efficacy and safety of sequential versus quadruple regimens as second line treatment for persistent Helicobacter pylori infection. METHODS: Prospective, randomized, open label trial was conducted at a large academic, tertiary care center in Israel...
2017: PloS One
Shailja C Shah, Steven H Itzkowitz, Lina Jandorf
Background/Aims: Although gastric cancer (GC) prevalence in the United States overall is low, there is significantly elevated risk in certain racial/ethnic groups. Providers caring for high-risk populations may not be fully aware of GC risk factors and may underestimate the potential for selective screening. Our aim was to identify knowledge gaps among healthcare providers with respect to GC. Methods: An Internet-based survey was distributed to primary care providers (PCPs) and gastroenterologists in New York City, which included questions regarding provider demographics, practice environment, GC risk factors, Helicobacter pylori , and screening practices...
January 15, 2018: Gut and Liver
Claire Alexandra Zhen Chew, Tong Fong Lye, Daphne Ang, Tiing Leong Ang
Helicobacter pylori (H. pylori) is an infection that has a role in causing dyspepsia and complications such as peptic ulcer disease and gastric malignancies. In the primary care setting, one can adopt a stepwise approach with the 'test-and-treat' strategy to manage H. pylori-associated dyspepsia in young patients without alarm symptoms. Empiric first-line therapies should be for a two-week duration; options include clarithromycin-containing triple therapy alone or with the addition of bismuth, concomitant therapy and bismuth quadruple therapy...
May 2017: Singapore Medical Journal
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