keyword
https://read.qxmd.com/read/36897573/critical-appraisal-of-international-guidelines-for-the-management-of-helicobacter-pylori-infection-in-case-of-dyspepsia
#21
REVIEW
Anaëlle Collin, François Mion, Amaniel Kefleyesus, Corinne Beets, Nemat Jaafari, Rémy Boussageon
BACKGROUND: Affecting between 20% and 90% of the world's population depending on the geo-socio-economic conditions, Helicobacter pylori (Hp) infection requires an adapted management because of the medico-economic stakes it generates. Also responsible for dyspepsia, the management of Hp infection differs in this context between international guidelines. OBJECTIVES: The primary outcome of the study was assessing the quality of current guidelines for HP eradication in dyspepsia...
April 2023: Helicobacter
https://read.qxmd.com/read/36768710/appropriateness-of-proton-pump-inhibitor-prescription-evaluated-by-using-serological-markers
#22
JOURNAL ARTICLE
Michele Russo, Kryssia Isabel Rodriguez-Castro, Marilisa Franceschi, Antonio Ferronato, Maria Piera Panozzo, Lorenzo Brozzi, Francesco Di Mario, Pellegrino Crafa, Giovanni Brandimarte, Antonio Tursi
Inappropriate prescription of proton pump inhibitors (PPI) has been widely reported, often lacking initial exclusion of Helicobacter pylori (HP) infection and evaluation of gastric functional status. The aim of this study was to evaluate the utility of gastric functional tests to define the acid output, as well as HP status, in order to better direct PPI therapy prescription. Dyspeptic patients without alarm symptoms from a primary care population were evaluated. For each patient, serum Pepsinogen I (PGI) and II (PGII), gastrin 17 (G17) and anti-HP IgG antibodies (Biohit, Oyj, Finland) were determined...
January 25, 2023: International Journal of Molecular Sciences
https://read.qxmd.com/read/36766972/diagnostic-and-therapeutic-management-of-helicobacter-pylori-infection-in-primary-care-perspective-of-application-in-france-and-narrative-review-of-the-literature
#23
REVIEW
Bernard Frèche, Julie Salvan, Marie Caroline Roch, Antoine Guerin, Elodie Poupin, Maxime Pichon, Christophe Burucoa
BACKGROUND: Helicobacter pylori ( Hp ) infection affects 30% to 40% of people in industrialized countries. AIM: This study aimed to synthesize knowledge on the diagnostic and therapeutic management of Hp infection in general practice in people under 40 years of age. METHOD: A narrative review of the literature with an inductive content analysis of the articles was performed. RESULTS: The extracted data (22 articles out of 106 included after screening of 965 articles) determined three areas of analysis: indications for screening, methods of screening and diagnosis by non-invasive tests, and treatment modalities...
January 30, 2023: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/36618210/prevalence-of-helicobacter-pylori-infection-among-patients-with-dyspepsia-and-other-gastrointestinal-diseases-in-king-abdulaziz-specialized-hospital-in-taif
#24
JOURNAL ARTICLE
Abrar A Oraijah, Mohammed H Shaqhan, Fatimah A Alhebshi, Rawan W Alsuwat, Abdullah H Algethami, Afnan H Alsofyani, Angham Ozayzan, Sameer A Altowairqi, Hesham H Alqurashi
INTRODUCTION: To estimate the prevalence of H. pylori in patients with dyspepsia as well as the prevalence of cancerous and precancerous nonmalignant lesions in patients with H. pylori . METHODS: A retrospective cohort study has been conducted at King Abdulaziz Specialist Hospital (KAASH), Ministry of Health (MOH) in Taif city in the Western province of Saudi Arabia among patients who underwent endoscopy between July 2019 and July 2021. Data were collected from the endoscopy log book and consisted of four sections; demographic data (age and gender), presenting symptoms and indications of endoscopy, endoscopic findings, and histopathological findings in endoscopic biopsies...
October 2022: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/36551403/evaluation-of-different-strategies-to-improve-the-management-of-helicobacter-pylori-infection-at-the-primary-care-level-training-sessions-increase-prescription-appropriateness-of-treatment-regimens
#25
JOURNAL ARTICLE
Enrique Alfaro, Samuel J Martínez-Domínguez, Viviana Laredo, Ángel Lanas, Carlos Sostres
Helicobacter pylori infection ( H. pylori ) is mainly managed at the primary care level. Our group previously performed a study demonstrating that providing specific counselling (SC) to primary care practitioners (PCPs) who requested a urea breath test (UBT) improved treatment management but not indications for H. pylori tests. SC was given in the form of a personal letter addressed to PCPs with UBT results which contained information about accepted UBT indications and a Helicobacter pylori treatment algorithm...
December 3, 2022: Antibiotics
https://read.qxmd.com/read/36407387/management-of-helicobacter-pylori-among-medical-doctors-working-in-khartoum-sudan-2019-a-cross-sectional-study
#26
JOURNAL ARTICLE
Azza A Abbas, Bushra I Sulieman, Elfatih M Malik
BACKGROUND: Various international guidelines have been developed regarding Helicobacter pylori ( H. pylori ) management, as it is infecting more than half of the world's population. Sudan's health system lacks guidelines regarding H. pylori management, leading to a discrepancy in practice. Investigating the current approach could be a step forward in the formulation of a national consensus in the management of H. pylori . METHODS: A cross-sectional study was conducted among medical doctors currently working in Khartoum, Sudan...
June 2022: African Health Sciences
https://read.qxmd.com/read/36363579/characteristics-and-patterns-of-proton-pump-inhibitors-prescribing-at-the-primary-health-care
#27
JOURNAL ARTICLE
Nataša Stojaković, Ana Golić Jelić, Svjetlana Stoisavljević Šatara, Nataša Bednarčuk, Miloš P Stojiljković, Ranko Škrbić
Background and objectives : the aim of this study was to analyse the utilisation of proton pump inhibitors (PPIs) during a 12-year period and to show the characteristics and patterns of their prescribing. Materials and methods : firstly, in the pharmacoepidemiological analyses the ATC/DDD methodology was used to assess the utilisation of PPIs in the Republic of Srpska. The annual PPI utilisation was expressed as a number of DDD/1000 inhabitants/year. Secondly, the cross-sectional surveys were used to reveal the characteristics of PPIs prescribing and medicines use, namely the dose, duration and indication, and possible adverse reactions...
November 10, 2022: Medicina
https://read.qxmd.com/read/36352959/clinical-and-endoscopic-study-of-dyspepsia-in-overweight-and-obese-patients
#28
JOURNAL ARTICLE
K M Farhanulla Basha, Bhumika T Vaishnav, Pragya Sharma, Nirali Thakkar, Minna Kartheek
OBJECTIVES: Globally, the prevalence of obesity is increasing at an alarming rate. Obese patients often suffer from chronic dyspeptic symptoms. The aim of the study was to know the gross and histologic upper gastrointestinal mucosal changes and the prevalence of Helicobacter Pylori (H. Pylori) infection in overweight and obese dyspeptic patients. MATERIALS AND METHODS: A cross-sectional, observational study was done on 100 patients with dyspepsia and a body mass index (BMI) of ≥25 kg/m2 ...
August 2022: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/36335970/helicobacter-pylori-eradication-for-primary-prevention-of-peptic-ulcer-bleeding-in-older-patients-prescribed-aspirin-in-primary-care-heat-a-randomised-double-blind-placebo-controlled-trial
#29
RANDOMIZED CONTROLLED TRIAL
Chris Hawkey, Anthony Avery, Carol A C Coupland, Colin Crooks, Jennifer Dumbleton, F D Richard Hobbs, Denise Kendrick, Michael Moore, Clive Morris, Gregory Rubin, Murray Smith, Diane Stevenson
BACKGROUND: Peptic ulcers in patients receiving aspirin are associated with Helicobacter pylori infection. We aimed to investigate whether H pylori eradication would protect against aspirin-associated ulcer bleeding. METHODS: We conducted a randomised, double-blind, placebo-controlled trial (Helicobacter Eradication Aspirin Trial [HEAT]) at 1208 primary care centres in the UK, using routinely collected clinical data. Eligible patients were aged 60 years or older who were receiving aspirin at a daily dose of 325 mg or less (with four or more 28-day prescriptions in the past year) and had a positive C13 urea breath test for H pylori at screening...
November 5, 2022: Lancet
https://read.qxmd.com/read/36232149/multicentric-study-to-assess-helicobacter-pylori-incidence-patient-reported-adverse-events-compliance-and-effectiveness-in-real-world-setting
#30
JOURNAL ARTICLE
André Mesquita, Carlos Rocha-Castro, Daniela Guimarães, Joana Costa, Joana Soutinho, Tiago Taveira-Gomes
Helicobacter pylori ( H. pylori ) plays an important role in chronic gastritis and globally it is estimated to be present in half of the world's population. In Portugal, prevalence reaches 85% and its eradication is recommended using quadruple antibiotic therapy, with or without bismuth. We intended to characterize the prescribed treatments evaluating effectiveness, adverse outcomes and compliance in a real-world setting in a primary care unit. A prospective multicenter observational cohort study was developed in five primary care units of Braga, Portugal...
October 7, 2022: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/36137766/helicobacter-pylori-in-new-zealand-current-diagnostic-trends-and-related-costs
#31
JOURNAL ARTICLE
Jan Kubovy, Murray L Barclay
AIM: To ascertain Helicobacter pylori (Hp) diagnosis trends and cost in a New Zealand cohort. METHODS: All Hp tests within Canterbury between 2013-2018 were retrospectively reviewed, exclusive of histology. Overall numbers for each test modality, expenditure and test positivity rates were calculated and matched to ethnicity. RESULTS: Over the six-year period, Hp testing increased 37% and associated cost by 42.6%, compared with population growth of 11...
September 23, 2022: New Zealand Medical Journal
https://read.qxmd.com/read/36087193/the-role-of-infections-in-the-causation-of-cancer-in-kenya
#32
REVIEW
Vivian C Tuei, Geoffrey K Maiyoh, Fidelis T Ndombera
Cancer constitutes a major health care burden in the world today with the situation worsening in resource poor settings as seen in most Sub-Saharan African (SSA) countries. Infections constitute by far the most common risk factors for cancer in SSA and being a typical country in this region, Kenya has experienced an upsurge in the incidence of various types of cancers in the last few decades. Although there is limited population-based data in Kenya of infections-associated cancers, this review provides an up-to-date literature-based discussion on infections-associated cancers, their pathogenesis, and preventive approaches in the country...
September 10, 2022: Cancer Causes & Control: CCC
https://read.qxmd.com/read/36082176/index-diagnoses-of-gastric-intestinal-metaplasia-in-the-united-states-patient-characteristics-endoscopic-findings-and-clinical-practice-patterns-at-a-large-tertiary-care-center
#33
JOURNAL ARTICLE
Sheeva K Parbhu, Shailja C Shah, Michael J Sossenheimer, John C Fang, Kathryn A Peterson, Andrew J Gawron
Background: Gastric intestinal metaplasia (GIM) is a premalignant gastric mucosal change that is often incidentally detected during esophagogastroduodenoscopy (EGD). Despite the established higher risk of gastric cancer associated with GIM, the incidence, prevalence, and outcomes data for GIM are limited in the United States (US), and practice patterns are highly variable. Objectives: Our primary objectives were to accurately identify incident histology-confirmed GIM cases and determine patient characteristics, endoscopy findings, Helicobacter pylori (HP) detection, and eradication treatment outcomes, as well as surveillance and follow-up recommendations...
2022: Therapeutic Advances in Gastroenterology
https://read.qxmd.com/read/36033766/current-knowledge-and-myths-about-celiac-disease-among-physicians-in-the-republic-of-kazakhstan-a-countrywide-cross-sectional-study
#34
JOURNAL ARTICLE
Aizhan Kozhakhmetova, Serzhan Aidossov, Aissulu Kapassova, Karlygash Borsoldayeva
Background: Celiac disease (CD) is a common genetically predisposed autoimmune condition affecting the gut and other organs. Disease awareness is one of the key components of early case identification. This study aimed to assess awareness about CD among primary care physicians, who are the front-liners in suspecting the diagnosis, and other medical specialists. Methods and findings: The questionnaire for this survey-based study was created based on the latest international guidelines on CD and included a consent form, 5 general questions (age, gender, etc...
2022: Frontiers in Public Health
https://read.qxmd.com/read/35975595/comparison-of-sequential-hybrid-and-quadruple-therapy-protocols-in-helicobacter-pylori-eradication-a-single-center-study
#35
JOURNAL ARTICLE
Ersin Kuloğlu, Bülent Albayrak, Hakan Dursun, Fatih Albayrak, Ömer Yılmaz
OBJECTIVE: Many treatment protocols are used in Helicobacter pylori eradication treatment within the framework of factors such as antibiotic resistance, drug side effects, patient compliance, and regional differences. MATERIALS AND METHODS: H. pylori was diagnosed with upper gastrointestinal system endoscopic biopsy in the Internal Diseases Gastroenterology Endoscopy Unit of Atatürk University Medical Faculty Hospital; a total of 229 patients over the age of 18 were evaluated prospectively by dividing them into 3 groups and applying 3 different H...
August 17, 2022: Eurasian Journal of Medicine
https://read.qxmd.com/read/35971900/helicobacter-pylori-infection-prevalence-in-ambulatory-settings-in-2017-2019-in-russia-the-data-of-real-world-national-multicenter-trial
#36
JOURNAL ARTICLE
Dmitry Bordin, Sergey Morozov, Roman Plavnik, Natalia Bakulina, Irina Voynovan, Irina Skibo, Vasily Isakov, Igor Bakulin, Dmitrii Andreev, Igor Maev
BACKGROUND: The recent data on the prevalence of Helicobacter pylori (H. pylori) infection in Russia are limited. The aim of the study was to compare Helicobacter pylori infection prevalence in ambulatory settings in Russia in 2017 and 2019 years. MATERIALS AND METHODS: Subjects visiting primary care centers were invited to take part in the study. H. pylori status was assessed by 13 C-urea breath test (UBT). Data on subjects' demography, previous treatment exposure, and place of residence were collected in all federal districts of Russia in 2017 and in 2019 calendar years and processed centrally...
August 16, 2022: Helicobacter
https://read.qxmd.com/read/35893411/guided-treatment-of-helicobacter-pylori-infections-with-non-invasive-pcr-tests-the-glory-days-of-primary-care
#37
EDITORIAL
Maxime Pichon, Bernard Freche, Christophe Burucoa
In the original article [...].
July 25, 2022: Journal of Clinical Medicine
https://read.qxmd.com/read/35873092/dyslipidemia-and-its-associated-factors-among-helicobacter-pylori-infected-patients-attending-at-university-of-gondar-comprehensive-specialized-hospital-gondar-north-west-ethiopia-a-comparative-cross-sectional-study
#38
JOURNAL ARTICLE
Marye Nigatie, Tadele Melak, Daniel Asmelash, Abebaw Worede
Background: Dyslipidemia refers to a lipid profile disturbance due to decreased high-density lipoprotein cholesterol and elevated low-density lipoprotein cholesterol, triglycerides, and total cholesterol. Helicobacter pylori infection can lead to some appetite-related disorders that may cause deregulated absorption of nutrients in the digestive system, contributing to changes in serum lipids. The purpose of this study is to assess dyslipidemia and its associated factors among H. pylori -infected patients attending at University of Gondar Comprehensive Specialized Hospital...
2022: Journal of Multidisciplinary Healthcare
https://read.qxmd.com/read/35578285/clinical-presentation-and-surgical-management-of-perforated-peptic-ulcer-in-a-tertiary-hospital-in-mogadishu-somalia-a-5-year-retrospective-study
#39
JOURNAL ARTICLE
Abdihamid Mohamed Ali, Abdulkadir Nor Mohamed, Yahye Garad Mohamed, Salim İdris Keleşoğlu
BACKGROUND: Perforated peptic ulcer is a common surgical emergency condition worldwide, which is associated with significant morbidity and mortality if early diagnosis and immediate surgical management were not carried out. Perforation occurs in roughly 5% of PUD patients during their lifetime; this study aimed to explore the wide range of clinical presentations, associated risk factors, complications, and surgical management of perforated peptic ulcer patients. METHODS: A 5-year retrospective observational study on the clinical presentation and surgical management of perforated peptic ulcer is carried out in a tertiary hospital in Mogadishu, Somalia, Department of General Surgery, from January 2017 to December 2021...
May 16, 2022: World Journal of Emergency Surgery: WJES
https://read.qxmd.com/read/35566209/gastric-cancer-pre-stage-detection-and-early-diagnosis-of-gastritis-using-serum-protein-signatures
#40
JOURNAL ARTICLE
Shahid Aziz, Faisal Rasheed, Rabaab Zahra, Simone König
BACKGROUND: A gastric cancer (GC) diagnosis relies on histopathology. Endoscopy rates are increasing. Helicobacter pylori infection is a major GC risk factor. In an effort to elucidate abundant blood biomarkers, and potentially reduce the number of diagnostic surgical interventions, we investigated sera and biopsies from a cohort of 219 H. pylori positive and negative patients diagnosed with GC, gastritis, and ulcers. This allowed the comparative investigation of the different gastroduodenal diseases, and the exclusion of protein changes resulting from bacterial infection or inflammation of the gastric mucosa when searching for GC-dependent proteins...
April 30, 2022: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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