Lana Sargent, Kristin M Zimmerman, Almutairi Mohammed, Matthew J Barrett, Huma Nawaz, Kathryn Wyman-Chick, Marissa Mackiewicz, Youssef Roman, Patricia Slattum, Sally Russell, Dave L Dixon, Sarah K Lageman, Sarah Hobgood, Leroy R Thacker, Elvin T Price
BACKGROUND: A growing body of research supports the negative impact of anticholinergic drug burden on physical frailty. However, prior research has been limited to homogeneous white European populations, and few studies have evaluated how anticholinergic burden tools compare in their measurement function and reliability with minority community-dwelling adult populations. This study investigated the association between anticholinergic drug exposure and frailty by conducting a sensitivity analysis using multiple anticholinergic burden tools in a diverse cohort...
October 19, 2023: Drugs & Aging