Jiangfang Feng, Yue Fei, Meng Gao, Xiangrui Meng, Dongfeng Zeng, Dehui Zou, Haige Ye, Yun Liang, Xiuhua Sun, Rong Liang, Hui Zhou, Xianhuo Wang, Huilai Zhang
Mantle cell lymphoma (MCL) is an uncommon and incurable B-cell lymphoma subtype that has an aggressive course. Hepatitis B virus (HBV) infection has been associated with an increased risk for B-cell lymphomas, and is characterized by distinct clinical and genetic features. Here, we showed that 9.5% of MCL Chinese patients were hepatitis B surface antigen positive (HBsAg+ ). Compared to HBsAg-negative (HBsAg- ) patients, HBsAg+ MCL patients had a greater incidence of elevated lactate dehydrogenase (LDH), but no difference was observed in the other clinical characteristics, including sex, age, ECOG ps, Ann Arbor stage, MIPI, extranodal involvement and Ki-67...
May 2024: Hematological Oncology