Hélène Faury, Ronan Le Guen, Vanessa Demontant, Christophe Rodriguez, Bérénice Souhail, Adrien Galy, Sarah Jolivet, Raphaël Lepeule, Jean-Winoc Decousser, Vincent Fihman, Paul-Louis Woerther, Guilhem Royer
Enterococcus faecium, a common resident of the human gastrointestinal tract, is also a major pathogen. Prompt initiation of appropriate treatment is essential to improve patient outcome in disseminated E. faecium infections. However, ampicillin resistance is frequent in this species, rendering treatment difficult. We used a comprehensive approach, including clinical data review, whole-genome sequencing, and mass spectrometry, to characterize ampicillin-susceptible (EFM-S) and ampicillin-resistant (EFM-R) isolates...
September 25, 2023: Microbiology Spectrum