Pedram Gerami, Klaus Busam, Alistair Cochran, Martin G Cook, Lyn M Duncan, David E Elder, Douglas R Fullen, Joan Guitart, Philip E LeBoit, Martin C Mihm, Victor G Prieto, Michael S Rabkin, Richard A Scolyer, Xiaowei Xu, Sook Jung Yun, Roxana Obregon, Pedram Yazdan, Chelsea Cooper, Bing Bing Weitner, Alfred Rademaker, Raymond L Barnhill
Predicting clinical behavior of atypical Spitz tumors remains problematic. In this study, we assessed interobserver agreement of diagnosis by 13 expert dermatopathologists for atypical Spitz tumors (n=75). We determined which histomorphologic features were most heavily weighted for their diagnostic significance by the experts and also which histomorphologic features had a statistically significant correlation with clinical outcome. There was a low interobserver agreement among the experts in categorizing lesions as malignant versus nonmalignant (κ=0...
July 2014: American Journal of Surgical Pathology