We have located links that may give you full text access.
JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Diving into the blue: in vivo microscopic characterization of the dermoscopic blue hue.
BACKGROUND: In dermoscopy the presence of a blue hue is a clue for malignancy, although a blue tint is sometimes observable in benign lesions.
OBJECTIVE: To identify the in vivo confocal microscopy correlates of the blue hue for improving diagnostic accuracy for melanoma.
METHODS: Fifty-seven melanomas, 41 junctional, 88 compound, and 27 Spitz nevi were studied by dermoscopy, confocal microscopy, and histopathology.
RESULTS: Confocal microscopy enabled the distinction between blue areas and blue veil, the former characterized by plump cells corresponding to melanophages and inflammatory infiltrate at histology, the latter by the contemporary presence of epidermal and dermal features consistent with diagnosis of melanoma, such as disarranged pattern, pagetoid cells, cytologic and architectural atypias, nonhomogeneous and cerebriform clusters, and dermal nucleated cells.
LIMITATIONS: Confocal microscopy failed to accurately distinguish Spitz nevi, because of the presence of cytoarchitectural disarray in the epidermis and the upper dermis.
CONCLUSION: Confocal microscopy enabled the in vivo identification of characteristic cytological substrates correlated with the blue features in dermoscopy.
OBJECTIVE: To identify the in vivo confocal microscopy correlates of the blue hue for improving diagnostic accuracy for melanoma.
METHODS: Fifty-seven melanomas, 41 junctional, 88 compound, and 27 Spitz nevi were studied by dermoscopy, confocal microscopy, and histopathology.
RESULTS: Confocal microscopy enabled the distinction between blue areas and blue veil, the former characterized by plump cells corresponding to melanophages and inflammatory infiltrate at histology, the latter by the contemporary presence of epidermal and dermal features consistent with diagnosis of melanoma, such as disarranged pattern, pagetoid cells, cytologic and architectural atypias, nonhomogeneous and cerebriform clusters, and dermal nucleated cells.
LIMITATIONS: Confocal microscopy failed to accurately distinguish Spitz nevi, because of the presence of cytoarchitectural disarray in the epidermis and the upper dermis.
CONCLUSION: Confocal microscopy enabled the in vivo identification of characteristic cytological substrates correlated with the blue features in dermoscopy.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app