Katarina Virijević, Marko N Živanović, Dalibor Nikolić, Nevena Milivojević, Jelena Pavić, Ivana Morić, Lidija Šenerović, Luka Dragačević, Philipp J Thurner, Manuel Rufin, Orestis G Andriotis, Biljana Ljujić, Marina Miletić Kovačević, Miloš Papić, Nenad Filipović
Here, an artificial intelligence (AI)-based approach was employed to optimize the production of electrospun scaffolds for in vivo wound healing applications. By combining polycaprolactone (PCL) and poly(ethylene glycol) (PEG) in various concentration ratios, dissolved in chloroform (CHCl3 ) and dimethylformamide (DMF), 125 different polymer combinations were created. From these polymer combinations, electrospun nanofiber meshes were produced and characterized structurally and mechanically via microscopic techniques, including chemical composition and fiber diameter determination...
April 25, 2024: ACS Applied Materials & Interfaces