Greg M Anderson, Jennifer W Hill, Ursula B Kaiser, Victor M Navarro, Ken K Ong, John R B Perry, Vincent Prevot, Manuel Tena-Sempere, Carol F Elias
An individual's nutritional status has a powerful effect on sexual maturation. Puberty onset is delayed in response to chronic energy insufficiency and is advanced under energy abundance. The consequences of altered pubertal timing for human health are profound. Late puberty increases the chances of cardiometabolic, musculoskeletal and neurocognitive disorders, whereas early puberty is associated with increased risks of adult obesity, type 2 diabetes mellitus, cardiovascular diseases and various cancers, such as breast, endometrial and prostate cancer...
February 2024: Nature Reviews. Endocrinology