journal
https://read.qxmd.com/read/36949099/cited1-mediates-sex-specific-regulation-of-food-intake-in-hypothalamic-neurons
#1
JOURNAL ARTICLE
Olivia Tysoe
No abstract text is available yet for this article.
March 22, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36941447/mammalian-models-of-diabetes-mellitus-with-a-focus-on-type-2-diabetes-mellitus
#2
REVIEW
Thomas A Lutz
Although no single animal model replicates all aspects of diabetes mellitus in humans, animal models are essential for the study of energy balance and metabolism control as well as to investigate the reasons for their imbalance that could eventually lead to overt metabolic diseases such as type 2 diabetes mellitus. The most frequently used animal models in diabetes mellitus research are small rodents that harbour spontaneous genetic mutations or that can be manipulated genetically or by other means to influence their nutrient metabolism and nutrient handling...
March 20, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36932176/revisiting-the-role-of-glucagon-in-health-diabetes-mellitus-and-other-metabolic-diseases
#3
REVIEW
Sofie Hædersdal, Andreas Andersen, Filip K Knop, Tina Vilsbøll
Insulin and glucagon exert opposing effects on glucose metabolism and, consequently, pancreatic islet β-cells and α-cells are considered functional antagonists. The intra-islet hypothesis has previously dominated the understanding of glucagon secretion, stating that insulin acts to inhibit the release of glucagon. By contrast, glucagon is a potent stimulator of insulin secretion and has been used to test β-cell function. Over the past decade, α-cells have received increasing attention due to their ability to stimulate insulin secretion from neighbouring β-cells, and α-cell-β-cell crosstalk has proven central for glucose homeostasis in vivo...
March 17, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36914759/a-perspective-on-treating-type-1-diabetes-mellitus-before-insulin-is-needed
#4
REVIEW
Danijela Tatovic, Parth Narendran, Colin M Dayan
Type 1 diabetes mellitus (T1DM) is a progressive autoimmune disease that starts long before a clinical diagnosis is made. The American Diabetes Association recognizes three stages: stage 1 (normoglycaemic and positive for autoantibodies to β-cell antigens); stage 2 (asymptomatic with dysglycaemia); and stage 3, which is defined by glucose levels consistent with the definition of diabetes mellitus. This Perspective focuses on the management of the proportion of individuals with early stage 3 T1DM who do not immediately require insulin; a stage we propose should be termed stage 3a...
March 13, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36899066/interventions-in-people-newly-diagnosed-with-type-1-diabetes-mellitus
#5
JOURNAL ARTICLE
Claire Greenhill
No abstract text is available yet for this article.
March 10, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36899065/large-study-on-hormone-therapy-for-transgender-youth-provides-reassurance-amid-treatment-politicization
#6
JOURNAL ARTICLE
Ximena Lopez, Laura E Kuper
No abstract text is available yet for this article.
March 10, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36882641/the-metabolic-benefits-of-exercise-induced-hepatic-autophagy
#7
JOURNAL ARTICLE
Claire Greenhill
No abstract text is available yet for this article.
March 7, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36869239/on-the-cutting-edge-perspectives-in-bioenergetics
#8
JOURNAL ARTICLE
Melia Granath-Panelo, Anna Krook, Jared Rutter, Shingo Kajimura
No abstract text is available yet for this article.
March 3, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36864152/glp1-the-early-steps-of-a-success-story
#9
JOURNAL ARTICLE
Rula Bany Bakar
No abstract text is available yet for this article.
March 2, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36864151/a-novel-resource-to-study-endometriosis-at-the-single-cell-level
#10
JOURNAL ARTICLE
Luz García-Alonso, Krina T Zondervan, Roser Vento-Tormo
No abstract text is available yet for this article.
March 2, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36828948/reprogramming-lymph-nodes-in-type-1-diabetes-mellitus
#11
JOURNAL ARTICLE
Shimona Starling
No abstract text is available yet for this article.
February 24, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36813865/sulfonylurea-secondary-failure-mechanism-identified
#12
JOURNAL ARTICLE
Olivia Tysoe
No abstract text is available yet for this article.
February 22, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36805052/consensus-statement-on-the-definition-and-classification-of-metabolic-hyperferritinaemia
#13
REVIEW
Luca Valenti, Elena Corradini, Leon A Adams, Elmar Aigner, Saleh Alqahtani, Marco Arrese, Edouard Bardou-Jacquet, Elisabetta Bugianesi, Jose-Manuel Fernandez-Real, Domenico Girelli, Hannes Hagström, Benjamin Henninger, Kris Kowdley, Guido Ligabue, Donald McClain, Fabrice Lainé, Koji Miyanishi, Martina U Muckenthaler, Alessia Pagani, Patrizia Pedrotti, Antonello Pietrangelo, Daniele Prati, John D Ryan, Laura Silvestri, C Wendy Spearman, Per Stål, Emmanuel A Tsochatzis, Francesca Vinchi, Ming-Hua Zheng, Heinz Zoller
Hyperferritinaemia is a common laboratory finding that is often associated with metabolic dysfunction and fatty liver. Metabolic hyperferritinaemia reflects alterations in iron metabolism that facilitate iron accumulation in the body and is associated with an increased risk of cardiometabolic and liver diseases. Genetic variants that modulate iron homeostasis and tissue levels of iron are the main determinants of serum levels of ferritin in individuals with metabolic dysfunction, raising the hypothesis that iron accumulation might be implicated in the pathogenesis of insulin resistance and the related organ damage...
February 17, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36792712/edc-exposure-in-3d-genome-memory-in-transgenerational-obesity
#14
JOURNAL ARTICLE
Xudong Zhang, Qi Chen
No abstract text is available yet for this article.
February 15, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36792711/aster-pathway-maintains-hepatic-cholesterol-homeostasis
#15
JOURNAL ARTICLE
Olivia Tysoe
No abstract text is available yet for this article.
February 15, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36782034/serine-slows-diabetic-neuropathy-in-mice
#16
JOURNAL ARTICLE
Shimona Starling
No abstract text is available yet for this article.
February 13, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36765197/the-effect-of-long-term-statin-use-on-diabetic-nephropathy
#17
JOURNAL ARTICLE
Claire Greenhill
No abstract text is available yet for this article.
February 10, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36732645/a-role-for-circulating-levels-of-uridine-in-regulating-hunger-and-food-intake
#18
JOURNAL ARTICLE
Claire Greenhill
No abstract text is available yet for this article.
February 2, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36726017/metabolism-and-exercise-the-skeletal-muscle-clock-takes-centre-stage
#19
REVIEW
Ryan A Martin, Mark R Viggars, Karyn A Esser
Circadian rhythms that influence mammalian homeostasis and overall health have received increasing interest over the past two decades. The molecular clock, which is present in almost every cell, drives circadian rhythms while being a cornerstone of physiological outcomes. The skeletal muscle clock has emerged as a primary contributor to metabolic health, as the coordinated expression of the core clock factors BMAL1 and CLOCK with the muscle-specific transcription factor MYOD1 facilitates the circadian and metabolic programme that supports skeletal muscle physiology...
February 1, 2023: Nature Reviews. Endocrinology
https://read.qxmd.com/read/36658216/variation-in-serotonin-2c-receptor-linked-with-obesity-and-behaviour
#20
JOURNAL ARTICLE
Shimona Starling
No abstract text is available yet for this article.
January 19, 2023: Nature Reviews. Endocrinology
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