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Cancer Imaging: the Official Publication of the International Cancer Imaging Society

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https://read.qxmd.com/read/30764876/comparative-analysis-of-the-value-of-diffusion-kurtosis-imaging-and-diffusion-weighted-imaging-in-evaluating-the-histological-features-of-endometrial-cancer
#1
Wei Yue, Nan Meng, Jing Wang, Wenling Liu, Xuejia Wang, Minghuan Yan, Dongming Han, Jingliang Cheng
PURPOSE: This study evaluated and compared the performances of diffusion kurtosis imaging (DKI) and diffusion-weighted imaging (DWI) for diagnosing and histologically grading endometrial cancer. MATERIALS AND METHODS: In this retrospective study, DKI and DWI data for 61 patients with endometrial cancer and 30 patients with a normal endometrium were analyzed, and the mean kurtosis (MK), mean diffusion coefficient (MD) and apparent diffusion coefficient (ADC) values for the endometrial cancer tissue and normal endometrial tissue were acquired...
February 14, 2019: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30744694/application-of-magnetic-resonance-diffusion-kurtosis-imaging-for-distinguishing-histopathologic-subtypes-and-grades-of-rectal-carcinoma
#2
Ziqiang Wen, Yan Chen, Xinyue Yang, Baolan Lu, Yiyan Liu, Bingqi Shen, Shenping Yu
BACKGROUND: To evaluate the diagnostic performance of diffusion kurtosis imaging (DKI) for distinguishing different histopathological subtypes and grades of rectal carcinoma and to compare DKI with conventional diffusion-weighted imaging (DWI). METHODS: This prospective study involved 132 patients with rectal carcinoma, comprising 116 with adenocarcinoma not otherwise specified (AC) and 16 with mucinous carcinoma (MC). High spatial resolution magnetic resonance (MR) and DKI sequences (b values of 0, 600, 1000, 1500 and 2000 s/mm2 ) were performed for pretreatment evaluation...
February 11, 2019: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30728073/ct-texture-analysis-a-potential-tool-for-predicting-the-fuhrman-grade-of-clear-cell-renal-carcinoma
#3
Zhan Feng, Qijun Shen, Ying Li, Zhengyu Hu
BACKGROUND: The purpose of this study was to analyze the image heterogeneity of clear-cell renal-cell carcinoma (ccRCC) by computer tomography texture analysis and to provide new objective quantitative imaging parameters for the pre-operative prediction of Fuhrman-grade ccRCC. METHODS: A retrospective analysis of 131 cases of ccRCCs was performed by manually depicting tumor areas. Then, histogram-based texture parameters were calculated. The texture-feature values between Fuhrman low- (Grade I-II) and high-grade (Grade III-IV) ccRCCs were compared by two independent sample t-tests (False Discovery Rate correction), and receiver operating characteristic curve (ROC) was used to evaluate the efficacy of using texture features to predict Fuhrman high- and low-grade ccRCCs...
February 6, 2019: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30728071/2020-vision-or-myopia-a-personal-perspective-on-the-future-of-cancer-imaging-and-an-introduction-to-the-sequels-to-the-how-i-read-series
#4
EDITORIAL
Rodney J Hicks
No abstract text is available yet for this article.
February 6, 2019: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30717792/the-utility-of-mri-histogram-and-texture-analysis-for-the-prediction-of-histological-diagnosis-in-head-and-neck-malignancies
#5
Noriyuki Fujima, Akihiro Homma, Taisuke Harada, Yukie Shimizu, Khin Khin Tha, Satoshi Kano, Takatsugu Mizumachi, Ruijiang Li, Kohsuke Kudo, Hiroki Shirato
BACKGROUND: To assess the utility of histogram and texture analysis of magnetic resonance (MR) fat-suppressed T2-weighted imaging (Fs-T2WI) for the prediction of histological diagnosis of head and neck squamous cell carcinoma (SCC) and malignant lymphoma (ML). METHODS: The cases of 57 patients with SCC (45 well/moderately and 12 poorly differentiated SCC) and 10 patients with ML were retrospectively analyzed. Quantitative parameters with histogram features (relative mean signal, coefficient of variation, kurtosis and skewness) and gray-level co-occurrence matrix (GLCM) features (contrast, correlation, energy and homogeneity) were calculated using Fs-T2WI data with a manual tumor region of interest (ROI)...
February 4, 2019: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30709369/prediction-of-high-nodal-burden-with-ultrasound-and-magnetic-resonance-imaging-in-clinically-node-negative-breast-cancer-patients
#6
Won Hwa Kim, Hye Jung Kim, So Mi Lee, Seung Hyun Cho, Kyung Min Shin, Sang Yub Lee, Jae Kwang Lim
BACKGROUND: Although the role of axillary imaging has been redirected for predicting high nodal burden rather than predicting nodal metastases since ACOSOG Z1011 trial, it remains unclear whether and how axillary lymph node (ALN) characteristics predicts high nodal burden. Our study was aimed to evaluate the predictive value of imaging characteristics of ALNs at ultrasound and magnetic resonance imaging (MRI) for prediction of high nodal burden (≥3 metastatic ALNs) in clinically node-negative breast cancer patients...
February 1, 2019: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30704527/computed-tomographic-features-of-adenoid-cystic-carcinoma-in-the-palate
#7
Wu-Tong Ju, Tong-Chao Zhao, Ying Liu, Yi-Ran Tan, Min-Jun Dong, Qi Sun, Li-Zhen Wang, Jiang Li, Lai-Ping Zhong
BACKGROUND: To evaluate the computed tomographic features and create a prediction model for clinical diagnosis of adenoid cystic carcinoma (ACC) in the palate with intact mucosa. METHODS: From March 2016 to May 2018, 102 patients with palatal tumors and intact mucosa, including 28 patients with a pathological diagnosis of ACC after surgery, were enrolled in this study. The patients' clinical symptoms, computed tomographic features and pathological diagnoses were recorded and analyzed...
January 31, 2019: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30670096/distribution-of-metastasis-in-the-brain-in-relation-to-the-hippocampus-a-retrospective-single-center-analysis-of-565-metastases-in-116-patients
#8
Qian Sun, Min Li, Gengming Wang, Hongbo Xu, Zelai He, Yongchun Zhou, Yan Zhou, Yufu Zhou, Hongwei Song, Hao Jiang
OBJECTIVE: To examine the distribution of brain metastases (BM) in relation to the hippocampus, so as to determine the risk of metastasis in the hippocampus, and thus provide experimental evidence for the hippocampal avoidance (HA) in patients with BM during radiotherapy. METHODS: (1) For the retrospective analysis of 116 patients diagnosed with malignancies, confirmed as BM, from December 2014 to December 2016 at the First Affiliated Hospital of Bengbu Medical College...
January 22, 2019: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30616608/whole-body-diffusion-weighted-mri-for-operability-assessment-in-patients-with-colorectal-cancer-and-peritoneal-metastases
#9
Raphaëla Carmen Dresen, Sofie De Vuysere, Frederik De Keyzer, Eric Van Cutsem, Hans Prenen, Ragna Vanslembrouck, Gert De Hertogh, Albert Wolthuis, André D'Hoore, Vincent Vandecaveye
BACKGROUND: Correct staging of patients with colorectal cancer is of utmost importance for the prediction of operability. Although computed tomography (CT) has a good overall performance, estimation of peritoneal cancer spread is a known weakness, a problem that cannot always be overcome by Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18 F-FDG-PET/CT); especially in infiltrative and miliary disease spread. Due to its high spatial and contrast resolution magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI) might have a better performance...
January 7, 2019: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30563571/-sentinel-lymph-node-imaging-with-sequential-spect-ct-lymphoscintigraphy-before-and-after-neoadjuvant-chemoradiotherapy-in-patients-with-cancer-of-the-oesophagus-or-gastro-oesophageal-junction-a-pilot-study
#10
Stefan Gabrielson, Jon A Tsai, Fuat Celebioglu, Magnus Nilsson, Ioannis Rouvelas, Mats Lindblad, Annie Bjäreback, Artur Tomson, Rimma Axelsson
BACKGROUND: In current best practise, curatively intended treatment for oesophageal cancer usually consists of neoadjuvant chemo-radiotherapy (nCRT) or perioperative chemotherapy, and oesophagectomy. Sentinel Lymph Node Biopsy (SLNB) has the potential to identify patients without lymph node metastases and thus improve the staging accuracy and influence treatment. The impact of neoadjuvant treatment on the lymphatic drainage of oesophageal cancers and subsequently the SLNB procedure in this tumour type has previously not been well studied...
December 18, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30547844/ct-texture-analysis-of-lung-adenocarcinoma-can-radiomic-features-be-surrogate-biomarkers-for-egfr-mutation-statuses
#11
Dongdong Mei, Yan Luo, Yan Wang, Jingshan Gong
OBJECTIVE: To investigate whether radiomic features can be surrogate biomarkers for epidermal growth factor receptor (EGFR) mutation statuses. MATERIALS AND METHODS: Two hundred ninety six consecutive patients, who underwent CT examinations before operation within 3 months and had EGFR mutations tested, were enrolled in this retrospective study. CT texture features were extracted using an open-source software with whole volume segmentation. The association between CT texture features and EGFR mutation statuses were analyzed...
December 14, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30541635/ideal-iq-in-an-oncologic-population-meeting-the-challenge-of-concomitant-liver-fat-and-liver-iron
#12
Sarah Eskreis-Winkler, Giuseppe Corrias, Serena Monti, Junting Zheng, Marinela Capanu, Simone Krebs, Maggie Fung, Scott Reeder, Lorenzo Mannelli
BACKGROUND: Cancer patients often have a history of chemotherapy, putting them at increased risk of liver toxicity and pancytopenia, leading to elevated liver fat and elevated liver iron respectively. T1-in-and-out-of-phase, the conventional MR technique for liver fat assessment, fails to detect elevated liver fat in the presence of concomitantly elevated liver iron. IDEAL-IQ is a more recently introduced MR fat quantification method that corrects for multiple confounding factors, including elevated liver iron...
December 12, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30537991/discrepancies-of-assessments-in-a-recist-1-1-phase-ii-clinical-trial-association-between-adjudication-rate-and-variability-in-images-and-tumors-selection
#13
Hubert Beaumont, Tracey L Evans, Catherine Klifa, Ali Guermazi, Sae Rom Hong, Mustapha Chadjaa, Zsuzsanna Monostori
BACKGROUND: In imaging-based clinical trials, it is common practice to perform double reads for each image, discrepant interpretations can result from these two different evaluations. In this study we analyzed discrepancies that occurred between local investigators (LI) and blinded independent central review (BICR) by comparing reader-selected imaging scans and lesions. Our goal was to identify the causes of discrepant declarations of progressive disease (PD) between LI and BICR in a clinical trial...
December 11, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30526690/preoperative-prediction-of-peripancreatic-vein-invasion-by-pancreatic-head-cancer
#14
Yi-Nan Shen, Cheng-Xiang Guo, Yao Pan, Yi-Wen Chen, Tian-Yu Tang, Yu-Wei Li, Jun-Hua Lu, Gang Jin, Ren-Yi Qin, Wei-Yun Yao, Ting-Bo Liang, Xue-Li Bai
BACKGROUND: Pancreatic adenocarcinoma is often diagnosed at an advanced stage when adjacent vascular invasion is present. Accurate evaluation of presence of vascular invasion can help guide therapy. The aim of this study was to construct a nomogram for preoperative prediction of peripancreatic vein invasion in patients with pancreatic head cancer. STUDY DESIGN: Data of patients with carcinoma head of pancreas and suspected peripancreatic invasion (n = 247) who underwent pancreatic resection with venous reconstruction between January 2012 and January 2017 at four academic institutions were retrospectively analyzed...
December 10, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30526674/comparison-of-gadoxetic-acid-versus-gadopentetate-dimeglumine-for-the-detection-of-hepatocellular-carcinoma-at-1-5-t-using-the-liver-imaging-reporting-and-data-system-li-rads-v-2017
#15
Ying Ding, Sheng-Xiang Rao, Wen-Tao Wang, Cai-Zhong Chen, Ren-Chen Li, Mengsu Zeng
PURPOSE: The goal of this study was to investigate the Liver Imaging Reporting and Data System (LI-RADS) v.2017 for the categorization of hepatocellular carcinomas (HCCs) with gadoxetic acid compared with gadopentetate dimeglumine-enhanced 1.5-T magnetic resonance imaging (MRI). MATERIAL AND METHODS: We included 141 high-risk patients with 145 pathologically-confirmed HCCs who first underwent gadopentetate dimeglumine-enhanced 1.5-T followed by gadoxetic acid-enhanced 1...
December 7, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30522522/the-eye-of-the-beholder-orbital-metastases-from-midgut-neuroendocrine-tumors-a-two-institution-experience
#16
Satya Das, Gino Pineda, Laura Goff, Rachel Sobel, Jordan Berlin, George Fisher
BACKGROUND: Metastases to the orbit occur rarely in midgut neuroendocrine tumor (NET) patients with only 20 cases reported to date. Patients typically present with bilateral involvement of the recti muscles and experience symptoms such as diplopia, proptosis, and decreased vision. Although orbital MRI remains the gold standard for imaging orbital disease, many orbital lesions are now detected on somatostatin-receptor (SSTR) based imaging such as 68Ga-DOTATATE PET-CT. CASE PRESENTATIONS: Patient 1 is a 72 year-old female with a well-differentiated G3 ileal NET who was incidentally diagnosed with orbital metastases during a hospitalization for pre-septal cellulitis in 2018...
December 6, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30518436/tumor-heterogeneity-in-gastrointestinal-stromal-tumors-of-the-small-bowel-volumetric-ct-texture-analysis-as-a-potential-biomarker-for-risk-stratification
#17
Cui Feng, Fangfang Lu, Yaqi Shen, Anqin Li, Hao Yu, Hao Tang, Zhen Li, Daoyu Hu
BACKGROUND: To explore whether volumetric CT texture analysis (CTTA) can serve as a potential imaging biomarker for risk stratification of small bowel gastrointestinal stromal tumors (small bowel-GISTs). METHODS: A total of 90 patients with small bowel-GISTs were retrospectively reviewed, of these, 26 were rated as high risk, 13 as intermediate risk, and 51 as low or very low risk. Histogram parameters extracted from CT images were compared among small bowel-GISTs with different risk levels by using one-way analysis of variance...
December 5, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30514387/endometrial-cancer-an-overview-of-novelties-in-treatment-and-related-imaging-keypoints-for-local-staging
#18
REVIEW
Stefania Rizzo, Marco Femia, Valentina Buscarino, Dorella Franchi, Annalisa Garbi, Vanna Zanagnolo, Maria Del Grande, Lucia Manganaro, Sarah Alessi, Caterina Giannitto, Francesca Ruju, Massimo Bellomi
Endometrial cancer is the most common gynaecologic malignancy in developed countries and its incidence is increasing. First-level treatment, if no contraindicated, is based on surgery. Pre-operative imaging is needed for evaluation of local extent and detection of distant metastases in order to guide treatment planning. Radiological evaluation, based on transvaginal ultrasound, MR and CT, can make the difference in disease management, paying special attention to assessment of entity of myometrial invasion, cervical stromal extension, and assessment of lymph nodal involvement and distant metastases...
December 4, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30477587/mono-bi-and-tri-exponential-diffusion-mri-modelling-for-renal-solid-masses-and-comparison-with-histopathological-findings
#19
Sophie van Baalen, Martijn Froeling, Marino Asselman, Caroline Klazen, Claire Jeltes, Lotte van Dijk, Bart Vroling, Pieter Dik, Bennie Ten Haken
PURPOSE: To compare diffusion tensor imaging (DTI), intravoxel incoherent motion (IVIM), and tri-exponential models of the diffusion magnetic resonance imaging (MRI) signal for the characterization of renal lesions in relationship to histopathological findings. METHODS: Sixteen patients planned to undergo nephrectomy for kidney tumour were scanned before surgery at 3 T magnetic resonance imaging (MRI), with T2 -weighted imaging, DTI and diffusion weighted imaging (DWI) using ten b-values...
November 26, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/30442202/diffusion-weighted-imaging-of-rectal-cancer-on-repeatability-and-cancer-characterization-an-effect-of-b-value-distribution-study
#20
Luguang Chen, Fu Shen, Zhihui Li, Haidi Lu, Yukun Chen, Zhen Wang, Jianping Lu
BACKGROUND: To explore the effect of b-value distributions on the repeatability and diagnostic performance of the ADC value in rectal cancer patients using multiple b-values and mono-exponential model diffusion-weighted imaging (DWI). METHODS: Thirty-two preoperative rectal cancer patients, without receiving neoadjuvant therapy, were scanned on a 3 Tesla magnetic resonance imaging scanner using DWI with 10 b-values ranging from 0 to 2000 s/mm2 . The apparent diffusion coefficient (ADC) value was calculated using a mono-exponential model and 31 b-value combinations consisting of 2 to 10 b-values were explored...
November 15, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
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