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Journals Cancer Imaging : the Official ...

Cancer Imaging : the Official Publication of the International Cancer Imaging Society

https://read.qxmd.com/read/38867342/impact-of-annual-trend-volume-of-low-dose-computed-tomography-for-lung-cancer-screening-on-overdiagnosis-overmanagement-and-gender-disparities
#21
JOURNAL ARTICLE
Chen Hsin-Hung, Tang En-Kuei, Wu Yun-Ju, Wu Fu-Zong
BACKGROUND: With the increasing prevalence of nonsmoking-related lung cancer in Asia, Asian countries have increasingly adopted low-dose computed tomography (LDCT) for lung cancer screening, particularly in private screening programs. This study examined how annual LDCT volume affects lung cancer stage distribution, overdiagnosis, and gender disparities using a hospital-based lung cancer database. METHODS: This study analyzed the annual utilized LDCT volume, clinical characteristics of lung cancer, stage shift distribution, and potential overdiagnosis...
June 12, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38863073/whole-tumoral-metabolic-heterogeneity-in-18-f-fdg-pet-ct-is-a-novel-prognostic-marker-for-neuroblastoma
#22
JOURNAL ARTICLE
Jun Liu, Qinghua Ren, Haonan Xiao, Siqi Li, Lingling Zheng, Xu Yang, Lijuan Feng, Ziang Zhou, Huanmin Wang, Jigang Yang, Wei Wang
BACKGROUND: Neuroblastoma (NB) is a highly heterogeneous tumor, and more than half of newly diagnosed NB are associated with extensive metastases. Accurately characterizing the heterogeneity of whole-body tumor lesions remains clinical challenge. This study aims to quantify whole-tumoral metabolic heterogeneity (WMH) derived from whole-body tumor lesions, and investigate the prognostic value of WMH in NB. METHODS: We retrospectively enrolled 95 newly diagnosed pediatric NB patients in our department...
June 11, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38863062/histogram-analysis-of-multiple-diffusion-models-for-predicting-advanced-non-small-cell-lung-cancer-response-to-chemoimmunotherapy
#23
JOURNAL ARTICLE
Yu Zheng, Liang Zhou, Wenjing Huang, Na Han, Jing Zhang
BACKGROUND: There is an urgent need to find a reliable and effective imaging method to evaluate the therapeutic efficacy of immunochemotherapy in advanced non-small cell lung cancer (NSCLC). This study aimed to investigate the capability of intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) histogram analysis based on different region of interest (ROI) selection methods for predicting treatment response to chemoimmunotherapy in advanced NSCLC. METHODS: Seventy-two stage III or IV NSCLC patients who received chemoimmunotherapy were enrolled in this study...
June 11, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38849902/patient-eligibility-for-trials-with-imaging-response-assessment-at-the-time-of-molecular-tumor-board-presentation
#24
JOURNAL ARTICLE
Nabeel Mansour, Kathrin Heinrich, Danmei Zhang, Michael Winkelmann, Maria Ingenerf, Lukas Gold, Konstantin Klambauer, Martina Rudelius, Frederick Klauschen, Michael von Bergwelt-Baildon, Jens Ricke, Volker Heinemann, C Benedikt Westphalen, Wolfgang G Kunz
PURPOSE: To assess the eligibility of patients with advanced or recurrent solid malignancies presented to a molecular tumor board (MTB) at a large precision oncology center for inclusion in trials with the endpoints objective response rate (ORR) or duration of response (DOR) based on Response Evaluation Criteria in Solid Tumors (RECIST version 1.1). METHODS: Prospective patients with available imaging at the time of presentation in the MTB were included. Imaging data was reviewed for objectifiable measurable disease (MD) according to RECIST v1...
June 7, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38831467/does-clinical-t1n0-ggn-really-require-checking-for-distant-metastasis-during-initial-staging-for-lung-cancer
#25
JOURNAL ARTICLE
Kazuhiro Imai, Nobuyasu Kurihara, Motoko Konno, Naoko Mori, Shinogu Takashima, Shoji Kuriyama, Ryo Demura, Haruka Suzuki, Yuzu Harata, Tatsuki Fujibayashi, Sumire Shibano, Akiyuki Wakita, Yushi Nagaki, Yusuke Sato, Kyoko Nomura, Yoshihiro Minamiya
BACKGROUND: Accurate clinical staging is crucial for selection of optimal oncological treatment strategies in non-small cell lung cancer (NSCLC). Although brain MRI, bone scintigraphy and whole-body PET/CT play important roles in detecting distant metastases, there is a lack of evidence regarding the indication for metastatic staging in early NSCLCs, especially ground-grass nodules (GGNs). Our aim was to determine whether checking for distant metastasis is required in cases of clinical T1N0 GGN...
June 3, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38831354/-18-f-fapi-adds-value-to-18-f-fdg-pet-ct-for-diagnosing-lymph-node-metastases-in-stage-i-iiia-non-small-cell-lung-cancer-a-prospective-study
#26
JOURNAL ARTICLE
Youcai Li, Yin Zhang, Zhihua Guo, Peng Hou, Jie Lv, Miao Ke, Shaoyu Liu, Siwen Li, Weiqiang Yin, Jianxing He, Xinlu Wang
BACKGROUND: This study investigates the value of fluorine 18 ([18 F])-labeled fibroblast activation protein inhibitor (FAPI) for lymph node (LN) metastases in patients with stage I-IIIA non-small cell lung cancer (NSCLC). METHODS: From November 2021 to October 2022, 53 patients with stage I-IIIA NSCLC who underwent radical resection were prospectively included. [18 F]-fluorodeoxyglucose (FDG) and [18 F]FAPI examinations were performed within one week. LN staging was validated using surgical and pathological findings...
June 3, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38802883/7-tesla-magnetic-resonance-spectroscopic-imaging-predicting-idh-status-and-glioma-grading
#27
JOURNAL ARTICLE
Cornelius Cadrien, Sukrit Sharma, Philipp Lazen, Roxane Licandro, Julia Furtner, Alexandra Lipka, Eva Niess, Lukas Hingerl, Stanislav Motyka, Stephan Gruber, Bernhard Strasser, Barbara Kiesel, Mario Mischkulnig, Matthias Preusser, Thomas Roetzer-Pejrimovsky, Adelheid Wöhrer, Michael Weber, Christian Dorfer, Siegfried Trattnig, Karl Rössler, Wolfgang Bogner, Georg Widhalm, Gilbert Hangel
INTRODUCTION: With the application of high-resolution 3D 7 Tesla Magnetic Resonance Spectroscopy Imaging (MRSI) in high-grade gliomas, we previously identified intratumoral metabolic heterogeneities. In this study, we evaluated the potential of 3D 7 T-MRSI for the preoperative noninvasive classification of glioma grade and isocitrate dehydrogenase (IDH) status. We demonstrated that IDH mutation and glioma grade are detectable by ultra-high field (UHF) MRI. This technique might potentially optimize the perioperative management of glioma patients...
May 27, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38783331/prognostic-and-predictive-value-of-interstitial-lung-abnormalities-and-egfr-mutation-status-in-patients-with-non-small-cell-lung-cancer
#28
JOURNAL ARTICLE
Xiaoli Xu, Min Zhu, Zixing Wang, Jialu Li, Tao Ouyang, Cen Chen, Kewu Huang, Yuhui Zhang, Yanli L Gao
BACKGROUND: To determine the predictive value of interstitial lung abnormalities (ILA) for epidermal growth factor receptor (EGFR) mutation status and assess the prognostic significance of EGFR and ILA in patients with non-small cell lung cancer (NSCLC). METHODS: We reviewed 797 consecutive patients with a histologically proven diagnosis of primary NSCLC from January 2013 to October 2018. Of these, 109 patients with NSCLC were found to have concomitant ILA. Multivariate logistic regression analysis was used to identify the significant clinical and computed tomography (CT) findings in predicting EGFR mutations...
May 23, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38773670/hca-dan-hierarchical-class-aware-domain-adaptive-network-for-gastric-tumor-segmentation-in-3d-ct-images
#29
JOURNAL ARTICLE
Ning Yuan, Yongtao Zhang, Kuan Lv, Yiyao Liu, Aocai Yang, Pianpian Hu, Hongwei Yu, Xiaowei Han, Xing Guo, Junfeng Li, Tianfu Wang, Baiying Lei, Guolin Ma
BACKGROUND: Accurate segmentation of gastric tumors from CT scans provides useful image information for guiding the diagnosis and treatment of gastric cancer. However, automated gastric tumor segmentation from 3D CT images faces several challenges. The large variation of anisotropic spatial resolution limits the ability of 3D convolutional neural networks (CNNs) to learn features from different views. The background texture of gastric tumor is complex, and its size, shape and intensity distribution are highly variable, which makes it more difficult for deep learning methods to capture the boundary...
May 21, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38773660/applying-dynamic-contrast-enhanced-mri-tracer-kinetic-models-to-differentiate-benign-and-malignant-soft-tissue-tumors
#30
JOURNAL ARTICLE
Aixin Gao, Hexiang Wang, Xiuyun Zhang, Tongyu Wang, Liuyang Chen, Jingwei Hao, Ruizhi Zhou, Zhitao Yang, Bin Yue, Dapeng Hao
BACKGROUND: To explore the potential of different quantitative dynamic contrast-enhanced (qDCE)-MRI tracer kinetic (TK) models and qDCE parameters in discriminating benign from malignant soft tissue tumors (STTs). METHODS: This research included 92 patients (41females, 51 males; age range 16-86 years, mean age 51.24 years) with STTs. The qDCE parameters (Ktrans , Kep , Ve , Vp , F, PS, MTT and E) for regions of interest of STTs were estimated by using the following TK models: Tofts (TOFTS), Extended Tofts (EXTOFTS), adiabatic tissue homogeneity (ATH), conventional compartmental (CC), and distributed parameter (DP)...
May 21, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38773634/mr-based-radiomics-predictive-modelling-of-egfr-mutation-and-her2-overexpression-in-metastatic-brain-adenocarcinoma-a-two-centre-study
#31
MULTICENTER STUDY
Yanran Li, Yong Jin, Yunling Wang, Wenya Liu, Wenxiao Jia, Jian Wang
OBJECTIVES: Magnetic resonance (MR)-based radiomics features of brain metastases are utilised to predict epidermal growth factor receptor (EGFR) mutation and human epidermal growth factor receptor 2 (HER2) overexpression in adenocarcinoma, with the aim to identify the most predictive MR sequence. METHODS: A retrospective inclusion of 268 individuals with brain metastases from adenocarcinoma across two institutions was conducted. Utilising T1-weighted imaging (T1 contrast-enhanced [T1-CE]) and T2 fluid-attenuated inversion recovery (T2-FLAIR) sequences, 1,409 radiomics features were extracted...
May 21, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38750551/a-ct-based-radiomics-analysis-to-predict-the-cn0-status-of-thyroid-papillary-carcinoma-a-two-center-study
#32
MULTICENTER STUDY
Zongbao Li, Yifan Zhong, Yan Lv, Jianzhong Zheng, Yu Hu, Yanyan Yang, Yunxi Li, Meng Sun, Siqian Liu, Yan Guo, Mengchao Zhang, Le Zhou
OBJECTIVES: To develop and validate radiomics model based on computed tomography (CT) for preoperative prediction of CN0 status in patients with papillary thyroid carcinoma (PTC). METHODS: A total of 548 pathologically confirmed LNs (243 non-metastatic and 305 metastatic) two distinct hospitals were retrospectively assessed. A total of 396 radiomics features were extracted from arterial-phase CT images, where the strongest features containing the most predictive potential were further selected using the least absolute shrinkage and selection operator (LASSO) regression method...
May 15, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38741207/preoperative-ct-based-radiomic-prognostic-index-to-predict-the-benefit-of-postoperative-radiotherapy-in-patients-with-non-small-cell-lung-cancer-a-multicenter-study
#33
MULTICENTER STUDY
Zeliang Ma, Yu Men, Yunsong Liu, Yongxing Bao, Qian Liu, Xu Yang, Jianyang Wang, Lei Deng, Yirui Zhai, Nan Bi, Luhua Wang, Zhouguang Hui
BACKGROUND: The value of postoperative radiotherapy (PORT) for patients with non-small cell lung cancer (NSCLC) remains controversial. A subset of patients may benefit from PORT. We aimed to identify patients with NSCLC who could benefit from PORT. METHODS: Patients from cohorts 1 and 2 with pathological Tany N2 M0 NSCLC were included, as well as patients with non-metastatic NSCLC from cohorts 3 to 6. The radiomic prognostic index (RPI) was developed using radiomic texture features extracted from the primary lung nodule in preoperative chest CT scans in cohort 1 and validated in other cohorts...
May 13, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38725034/a-clinical-radiomics-nomogram-based-on-dual-layer-spectral-detector-ct-to-predict-cancer-stage-in-pancreatic-ductal-adenocarcinoma
#34
JOURNAL ARTICLE
Linxia Wu, Chunyuan Cen, Xiaofei Yue, Lei Chen, Hongying Wu, Ming Yang, Yuting Lu, Ling Ma, Xin Li, Heshui Wu, Chuansheng Zheng, Ping Han
BACKGROUND: This study aimed to evaluate the efficacy of radiomics signatures derived from polyenergetic images (PEIs) and virtual monoenergetic images (VMIs) obtained through dual-layer spectral detector CT (DLCT). Moreover, it sought to develop a clinical-radiomics nomogram based on DLCT for predicting cancer stage (early stage: stage I-II, advanced stage: stage III-IV) in pancreatic ductal adenocarcinoma (PDAC). METHODS: A total of 173 patients histopathologically diagnosed with PDAC and who underwent contrast-enhanced DLCT were enrolled in this study...
May 9, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38720391/impact-of-deep-learning-image-reconstruction-on-volumetric-accuracy-and-image-quality-of-pulmonary-nodules-with-different-morphologies-in-low-dose-ct
#35
JOURNAL ARTICLE
L D'hondt, C Franck, P-J Kellens, F Zanca, D Buytaert, A Van Hoyweghen, H El Addouli, K Carpentier, M Niekel, M Spinhoven, K Bacher, A Snoeckx
BACKGROUND: This study systematically compares the impact of innovative deep learning image reconstruction (DLIR, TrueFidelity) to conventionally used iterative reconstruction (IR) on nodule volumetry and subjective image quality (IQ) at highly reduced radiation doses. This is essential in the context of low-dose CT lung cancer screening where accurate volumetry and characterization of pulmonary nodules in repeated CT scanning are indispensable. MATERIALS AND METHODS: A standardized CT dataset was established using an anthropomorphic chest phantom (Lungman, Kyoto Kaguku Inc...
May 9, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38720384/multi-institutional-validation-of-a-radiomics-signature-for-identification-of-postoperative-progression-of-soft-tissue-sarcoma
#36
MULTICENTER STUDY
Yuan Yu, Hongwei Guo, Meng Zhang, Feng Hou, Shifeng Yang, Chencui Huang, Lisha Duan, Hexiang Wang
BACKGROUND: To develop a magnetic resonance imaging (MRI)-based radiomics signature for evaluating the risk of soft tissue sarcoma (STS) disease progression. METHODS: We retrospectively enrolled 335 patients with STS (training, validation, and The Cancer Imaging Archive sets, n = 168, n = 123, and n = 44, respectively) who underwent surgical resection. Regions of interest were manually delineated using two MRI sequences...
May 8, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38715096/superiority-of-18-f-fapi-42-pet-ct-in-the-detection-of-primary-tumor-and-management-of-appendiceal-neoplasm-to-18-f-fdg-pet-ct-and-ce-ct
#37
COMPARATIVE STUDY
Ye Dong, Shun Huang, Hubing Wu, Min Cao, Yanchao Huang, Ganghua Tang, Wenlan Zhou
BACKGROUND: In the present study, we investigated the value of 18 F-fibroblast-activation protein inhibitor (FAPI) positron emission tomography/computed tomography (18 F-FAPI-42 PET/CT) to preoperative evaluations of appendiceal neoplasms and management for patients. METHODS: This single-center retrospective clinical study, including 16 untreated and 6 treated patients, was performed from January 2022 to May 2023 at Southern Medical University Nanfang Hospital. Histopathologic examination and imaging follow-up served as the reference standard...
May 7, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38711135/comparison-of-quantitative-whole-body-pet-parameters-on-68-ga-ga-psma-11-pet-ct-using-ordered-subset-expectation-maximization-osem-vs-bayesian-penalized-likelihood-bpl-reconstruction-algorithms-in-men-with-metastatic-castration-resistant-prostate-cancer
#38
COMPARATIVE STUDY
Narjess Ayati, Lachlan McIntosh, James Buteau, Ramin Alipour, Michal Pudis, Nicholas Daw, Price Jackson, Michael S Hofman
BACKGROUND: PSMA PET/CT is a predictive and prognostic biomarker for determining response to [177 Lu]Lu-PSMA-617 in patients with metastatic castration resistant prostate cancer (mCRPC). Thresholds defined to date may not be generalizable to newer image reconstruction algorithms. Bayesian penalized likelihood (BPL) reconstruction algorithm is a novel reconstruction algorithm that may improve contrast whilst preventing introduction of image noise. The aim of this study is to compare the quantitative parameters obtained using BPL and the Ordered Subset Expectation Maximization (OSEM) reconstruction algorithms...
May 6, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38702821/head-to-head-comparison-of-68-ga-ga-dota-fapi-04-and-18-f-fdg-pet-ct-for-the-evaluation-of-tonsil-cancer-and-lymph-node-metastases-a-single-centre-retrospective-study
#39
COMPARATIVE STUDY
Mengjing Ji, Guang Ma, Cheng Liu, Bingxin Gu, Xinyue Du, Xiaomin Ou, Xiaoping Xu, Shaoli Song, Zhongyi Yang
BACKGROUND: This study aimed to compare the diagnostic value of [68  Ga]Ga-DOTA-FAPI-04 and [18 F]FDG PET/CT imaging for primary lesions and metastatic lymph nodes in patients with tonsil cancer. METHOD: Twenty-one tonsil cancer patients who underwent [68  Ga]Ga-DOTA-FAPI-04 and [18 F]FDG PET/CT scans within two weeks in our centre were retrospectively enrolled. The maximum standardized uptake value (SUVmax) and tumor-to-background ratio (TBR) of the two tracers were compared by using the Mann‒Whitney U test...
May 3, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/38654284/radiomics-signature-for-dynamic-changes-of-tumor-infiltrating-cd8-t-cells-and-macrophages-in-cervical-cancer-during-chemoradiotherapy
#40
JOURNAL ARTICLE
Kang Huang, Xuehan Huang, Chengbing Zeng, Siyan Wang, Yizhou Zhan, Qingxin Cai, Guobo Peng, Zhining Yang, Li Zhou, Jianzhou Chen, Chuangzhen Chen
BACKGROUND: Our previous study suggests that tumor CD8+ T cells and macrophages (defined as CD68+ cells) infiltration underwent dynamic and heterogeneous changes during concurrent chemoradiotherapy (CCRT) in cervical cancer patients, which correlated with their short-term tumor response. This study aims to develop a CT image-based radiomics signature for such dynamic changes. METHODS: Thirty cervical squamous cell carcinoma patients, who were treated with CCRT followed by brachytherapy, were included in this study...
April 23, 2024: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
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