Moran Hausman-Kedem, Rachelle Herring, Marcela D Torres, Jonathan D Santoro, Matsanga Leyila Kaseka, Carolina Vargas, Giulia Amico, Marta Bertamino, Deepti Nagesh, Jo Tilley, Allyson Schenk, Shay Ben-Shachar, Patricia L Musolino
Stroke in childhood has multiple etiologies, which are mostly distinct from those in adults. Genetic discoveries over the last decade pointed to monogenic disorders as a rare but significant cause of ischemic stroke in children and young adults, including small vessel and arterial ischemic stroke. These discoveries contributed to the understanding that stroke in children may be a sign of an underlying genetic disease. The identification of these diseases requires a detailed medical and family history collection, a careful clinical evaluation for the detection of systemic symptoms and signs, and neuroimaging assessment...
December 2022: Seminars in Pediatric Neurology