journal
https://read.qxmd.com/read/38734205/prognostic-value-of-stress-myocardial-perfusion-imaging-across-the-spectrum-of-cardiovascular-risk
#41
JOURNAL ARTICLE
Vinh D Doan, Chengyi Zheng, James Onwuzurike, Aiyu Chen, Yi-Lin Wu, Ming-Sum Lee
BACKGROUND: Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is widely used to identify ischemia. There is limited research to evaluate if there is a risk threshold below which SPECT-MPI may not add significant prognostic value. METHODS: Between January 1, 2012, and December 31, 2018, individuals who underwent SPECT-MPI were stratified into four risk groups. The primary outcome was acute myocardial infarction (MI) or death. Multivariable Cox proportional hazards regression analysis was used to calculated HRs with 95% CIs...
May 9, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38734204/stenting-of-isolated-pulmonary-artery-stenosis-in-an-adult-patient-with-rnf213-p-arg4810lys-variant
#42
Misaki Kanezawa, Hiroto Shimokawahara, Ayane Miyagi, Hiromi Matsubara
Isolated peripheral pulmonary artery stenosis (PPAS) in adulthood related to the RNF213 p.Arg4810Lys variant is characterized by bilateral nonuniform pulmonary artery stenoses without congenital heart disease or systemic congenital syndromes. Progressive stenoses worsening results in elevated pulmonary artery pressure (PAP), eventually leading to patient fatality. However, established treatments for PPAS are currently lacking. We present the case of a 40-year-old woman diagnosed with isolated PPAS with the RNF213 p...
May 9, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38729604/contemporary-outcomes-of-acute-coronary-syndromes-in-indigenous-compared-with-non-indigenous-patients-a-northern-saskatchewan-perspective
#43
JOURNAL ARTICLE
Jay S Shavadia, Udoka Okpalauwaekwe, Minyoung Kim, Jason Orvold, Colin Pearce, Alexandra King, Kehinde Ametepee, Haissam Haddad
BACKGROUND: In patients presenting with an acute coronary syndrome (ACS), the impact of efforts leveraged at bridging historical care gaps between Indigenous and non-Indigenous patients remains limited. METHODS: For consecutive ACS presentations (STEMI and NSTEMI/UA, respectively) at the Royal University Hospital, Saskatoon, we compared between self-identified Indigenous and non-Indigenous patients their demographics, treatments and all-cause mortality (in-hospital and 3-years)...
May 8, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38705272/the-relationship-between-perceived-parenting-practices-and-anxiety-in-adults-with-congenital-heart-disease
#44
JOURNAL ARTICLE
Cylia Houchi, Marie-Joëlle Marcil, Kishani Nadarajah, Geneviève A Mageau, Paul Khairy, Marie-France Marin, Mariève Cossette, Marie-Pierre Dubé, Marie-A Chaix, François-Pierre Mongeon, Annie Dore, Blandine Mondésert, Reda Ibrahim, Judith Brouillette
BACKGROUND: Patients with congenital heart disease (CHD) and their parents face challenges throughout their lives that can lead to anxiety lasting into adulthood. We aim to assess the association between perceived parenting practices and anxiety beyond pediatric medical-surgical histories in adults with CHD. METHODS: A cross-sectional study of adults with CHD was conducted at the Montreal Heart Institute (MHI). Perception of parental practices during childhood was retrospectively assessed using validated self-report questionnaires, while anxiety in adulthood was assessed with the Hospital Anxiety and Depression Scale (HADS)...
May 3, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38704145/malnutrition-a-predominant-issue-in-hospitalized-older-adults-yet-an-undeveloped-research-space-with-huge-potential
#45
LETTER
Deirdre E O'Neill, George A Heckman, Michelle M Graham
No abstract text is available yet for this article.
May 2, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38692432/complex-visual-hallucinations-associated-with-ranolazine-treatment-a-case-report
#46
Karla Prebil, Anja Kokalj Palandacic, Polona Rus Prelog
Ranolazine is a piperazine derivative and is indicated for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled or intolerant to first-line antianginal therapies. Visual hallucinations together with neurological symptoms have been described with ranolazine treatment. In this case report, we describe a case of an elderly diabetic patient with chronic angina pectoris who developed visual hallucinations during an acute worsening of kidney function after tolerating ranolazine well for six years...
April 29, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38692431/oxygenated-right-ventricular-assist-device-oxyrvad-the-right-bridge-for-severe-respiratory-and-right-ventricular-failure
#47
EDITORIAL
Tiffany Yuen, Varinder K Randhawa
No abstract text is available yet for this article.
April 29, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38692430/collagen-triple-helix-repeat-containing-protein-1-is-a-novel-biomarker-of-right-ventricular-involvement-in-pulmonary-hypertension
#48
JOURNAL ARTICLE
Tetsuro Yokokawa, Kazuto Nishiura, Masataka Katahira, Yu Sato, Shunsuke Miura, Akihiko Sato, Takeshi Shimizu, Tomofumi Misaka, Takamasa Sato, Takashi Kaneshiro, Masayoshi Oikawa, Akiomi Yoshihisa, Koichi Sugimoto, Kenji Fukushima, Kazuhiko Nakazato, Yasuchika Takeishi
BACKGROUND: Pulmonary hypertension leads to right ventricular failure, which is a major determinant of prognosis. Circulating biomarkers for right ventricular function are poorly explored in pulmonary hypertension. This study aimed to clarify the significance of collagen triple helix repeat-containing protein 1 (CTHRC1) as a biomarker of right ventricular failure in pulmonary hypertension. METHODS: A monocrotaline-induced pulmonary hypertension rat model was used to evaluate right ventricular CTHRC1 expression and its relationship with fibrosis...
April 29, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38679319/recurrent-pericardial-effusions-and-intrapericardial-thrombi-of-unknown-etiology
#49
Paul Mundra, Richard Whitlock, Omar Ibrahim, Filipe Cirne
This is a case of a 76-year-old male with an initial presentation consistent with idiopathic pericarditis. He presented repeatedly with recurrent pericardial effusions and intrapericardial thrombi of unknown etiology. Surgical evacuation of the thrombi was performed twice, and the second surgery demonstrated a cardiac tumour. Cardiac MRI and pathology were consistent with angiosarcoma. In cases of recurrent pericardial effusions and thrombi, we recommend a high index of suspicion for cardiac tumours. Further, we recommend early consideration of cardiac MRI or PET and early referral to imaging specialists and cardiac surgeons with experience in cardiac tumours...
April 26, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38670458/wherefore-frailty-an-opportunity-to-improve-cardiac-care
#50
JOURNAL ARTICLE
George A Heckman, Kenneth Rockwood
As with many conditions of aging, cardiovascular disease is increasingly common. Ensuring optimal care requires that we adapt care to best support those patients living with frailty. Frailty is a multiply determined state of graded vulnerability to stressors that becomes more prevalent with age. It better predicts risk than does chronological age, and intrinsically affects individuals differently: some chronologically young persons may be frailer than chronologically older ones. Frailty affects how illness presents and can limit treatment choices...
April 24, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38670457/effectiveness-and-safety-of-a-novel-intravascular-lithotripsy-system-for-severe-coronary-calcification-calci-crack-trial
#51
JOURNAL ARTICLE
Qiuhe Wang, Wenshuai Ma, Dongwei Zhang, Wei Zhang, Jian An, Kefei Dou, Ping Li, Jun Jiang, Yong He, Qian Tong, Xiaoyong Zhang, Wenyue Pang, Chunguang Qiu, Qing Yang, Xinqun Hu, Lin Zhong, Xiang Cheng, Xiaoping Peng, Jing Kan, Junjie Zhang, Bin Zhang, Yan Li
BACKGROUND: Intravascular lithotripsy is effective and safe for managing coronary calcification; however, available devices are limited, and complex lesions have been excluded in previous studies. This study aimed to investigate the effectiveness and safety of a novel intravascular lithotripsy system for severe calcification in a population with complex lesions. METHODS: CALCI-CRACK (ChiCTR2100052058) is a prospective, single-arm, multicenter study. The primary endpoint was the procedural success rate...
April 24, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38670456/applying-artificial-intelligence-for-phenotyping-of-inherited-arrhythmia-syndromes
#52
REVIEW
Sophie Sigfstead, River Jiang, Robert Avram, Brianna Davies, Andrew D Krahn, Christopher C Cheung
Inherited arrhythmia disorders account for a significant proportion of sudden cardiac death, particularly among young individuals. Recent advances in our understanding of these syndromes have improved patient diagnosis and care, yet certain clinical gaps remain, particularly within case ascertainment, access to genetic testing and risk stratification. Artificial intelligence (AI), specifically machine learning and its subset deep learning, present promising solutions to these challenges. The capacity of AI to process vast amounts of patient data and identify disease patterns differentiates them from traditional methods, which are time and resource intensive...
April 24, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38663528/the-fontan-fenestration-what-are-its-long-term-implications
#53
EDITORIAL
Giulia Pula, Kevin C Harris
No abstract text is available yet for this article.
April 23, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38663527/social-determinants-of-health-in-cardiovascular-disease-a-call-to-action
#54
EDITORIAL
Dennis T Ko, James M Brophy, Mamas A Mamas, Brian W McCrindle, Harindra C Wijeysundera
No abstract text is available yet for this article.
April 23, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38642847/navigating-the-landscape-of-medical-device-advisories-a-special-report-from-the-canadian-heart-rhythm-society-device-advisory-committee
#55
JOURNAL ARTICLE
Jason G Andrade, Alice Virani, Amelia Staunton, Marc Bains, Derek S Chew, Nathaniel M Hawkins, Jacqueline Joza, Clarence Khoo, Jaimie Manlucu, Francois Philippon, Calum Redpath, Laurence Sterns
Cardiac implantable electronic devices (CIED) are often important for regulating cardiac rate and rhythm. Pacemakers and defibrillators are among the top 10 most-implanted medical devices, with >1.5 million devices implanted annually. While millions of patients have benefited with improved quality of life and survival, CIED-systems are increasingly complex and do not always perform according to expectations. Advisory notices communicate important information about the safety and performance of a medical device to healthcare providers and patients...
April 18, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38621475/exploring-the-pathophysiological-interplay-between-multidimensional-frailty-and-heart-failure-prognosis
#56
LETTER
Arif Albulushi
No abstract text is available yet for this article.
April 13, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38614313/unlocking-sex-specific-therapies-in-aortic-stenosis-a-leap-forward-with-angiotensin-ii-receptor-blockers
#57
EDITORIAL
Elizabeth Hillier, Judy Luu
No abstract text is available yet for this article.
April 11, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38604339/heart-failure-with-preserved-ejection-fraction-in-the-elderly-basic-mechanisms-and-clinical-considerations
#58
REVIEW
Kimia Gharagozloo, Mozhdeh Mehdizadeh, George Heckman, Robert A Rose, Jonathan Howlett, Susan E Howlett, Stanley Nattel
Heart failure (HF) with preserved ejection fraction (HFpEF) refers to a clinical condition in which the signs of HF, such as pulmonary congestion, peripheral edema and increased natriuretic-peptide levels, are present despite normal ejection-fractions and the absence of other causes (e.g. pericardial disease). The ejection-fraction cutoff for the definition of HFpEF has varied in the past, but recent society guidelines have settled on a consensus of 50%. HFpEF is particularly common in the elderly. The aim of this narrative review is to summarize the available literature regarding HFpEF in the elderly in terms of evidence for the age-dependence, specific clinical features and underlying mechanisms...
April 9, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38604338/optimal-transfusion-threshold-for-anemic-patients-presenting-with-myocardial-infarction-and-heart-failure-dream-or-reality
#59
EDITORIAL
Ren Jie Robert Yao, Christopher B Fordyce
No abstract text is available yet for this article.
April 9, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38604337/right-ventricular-assist-device-with-an-oxygenator-for-the-management-of-combined-right-ventricular-and-respiratory-failure-a-systematic-review
#60
REVIEW
Juliette Beaulieu, Christine Vu, Sanjog Kalra, Hamza Ouazani Chahdi, Julie Cousineau, Alexis Matteau, Samer Mansour, E Marc Jolicoeur, Sabrina Jacques, Bénédicte Nauche, Renata Podbielski, Pasquale Ferraro, Charles Poirier, Brian J Potter
BACKGROUND: Severe lung disease frequently presents with both refractory hypoxemia and right ventricular (RV) failure. OxyRVAD is an extra-corporeal membrane oxygenation (ECMO) configuration of RV bypass that also supplements gas exchange. This systematic review summarizes the available literature regarding the use of OxyRVAD in the setting of severe lung disease with associated RV failure. METHODS: PubMed, Embase, and Google Scholar were queried on September 27th , 2023, for articles describing the use of an OxyRVAD configuration...
April 9, 2024: Canadian Journal of Cardiology
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