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International Journal of Cardiology

Lorenzo Azzalini, Enrico Poletti, Francesca Lombardo, Alessandra Laricchia, Alessandro Beneduce, Silvia Moscardelli, Barbara Bellini, Davide Maccagni, Alberto Cappelletti, Marco B Ancona, Mauro Carlino, Alaide Chieffo, Antonio Colombo, Matteo Montorfano
BACKGROUND: Complex percutaneous coronary intervention (PCI) is associated with increased procedural challenges and high contrast load. We aimed to evaluate the association between complex PCI and contrast-induced nephropathy (CIN). METHODS: This single-center retrospective study included all-comers undergoing PCI between January 2012 and December 2016. Complex PCI was defined as a procedure with ≥1 of the following characteristics: 3 vessels treated, ≥3 stents implanted, two-stent bifurcation intervention, total stent length >60mm, PCI on a chronic total occlusion, saphenous vein graft, or left main, protected PCI, use of rotational/laser atherectomy...
April 14, 2019: International Journal of Cardiology
Kenichiro Yamamura, Ichiro Sakamoto, Eiji Morihana, Yuichiro Hirata, Hazumu Nagata, Yuzo Yamasaki, Yukihiko Okumura, Kenichi Kohashi, Kazuhiro Koto, Hiroyuki Tsutsui, Shouichi Ohga
BACKGROUND: Congestive hepatopathy and hepatocellular carcinoma is a serious complication after Fontan procedure. Liver fibrosis due to hepatic congestion could occur also in adult patients after repair of tetralogy of Fallot (rTOF). However, the incidence and severity remain unclear. METHODS: A total of 111 patients with adult congenital heart disease between 2009 and 2016 were enrolled. Liver fibrosis markers and hemodynamic parameters assessed by cardiac magnetic resonance imaging and catheterization were analyzed in 50 rTOF patients having significant pulmonary regurgitation and/or stenosis, 50 Fontan patients and 11 controls...
April 11, 2019: International Journal of Cardiology
Britt Borregaard, Jordi Sanchez Dahl, Lars Peter Schødt Riber, Ola Ekholm, Kirstine Lærum Sibilitz, Marc Weiss, Jan Sørensen, Selina Kikkenborg Berg, Jacob Eifer Møller
BACKGROUND: Unplanned readmissions after heart valve surgery are common, and constitute a significant burden for the patient and the health care system. The objective was to investigate the effect of individualised follow-up after open heart valve surgery on a composite endpoint of first unplanned cardiac hospital readmission or all-cause mortality within 180 days of discharge. METHODS: The study is a prospective cohort study comparing the composite endpoint in patients undergoing early, individualised and intensified follow-up after heart valve surgery with a propensity matched historical control group...
April 11, 2019: International Journal of Cardiology
Karsten Keller, Lukas Hobohm, Thomas Münzel, Mir Abolfazl Ostad
BACKGROUND: Seasonal variation regarding the incidence and the short-term mortality of acute myocardial infarction (MI) was frequently reported, but data about sex-specific differences are sparse. METHODS: We analysed the impact of seasons and temperature on incidence and in-hospital mortality of patients with acute MI in Germany between 2005 and 2015. RESULTS: The nationwide sample comprised 3,008,188 hospitalizations of MI patients (2005-2015)...
April 11, 2019: International Journal of Cardiology
Ulrika Ljung Faxén, Lars H Lund, Nicola Orsini, Anna Strömberg, Daniel C Andersson, Cecilia Linde, Ulf Dahlström, Gianluigi Savarese
OBJECTIVE: The aim was to assess sex-specific differences in N-terminal B-type natriuretic peptide (NT-proBNP) regarding concentrations, predictors of high concentrations, and prognostic role, in a large and unselected population with chronic heart failure (HF) with preserved (HFpEF), mid-range (HFmrEF), and reduced ejection fraction (HFrEF). METHODS AND RESULTS: In 9847 outpatients with HFpEF, HFmrEF, and HFrEF (49 vs. 35 vs. 25% females, respectively) from the Swedish HF Registry, median NT-proBNP concentrations were 1598 ng/L in females vs...
April 11, 2019: International Journal of Cardiology
Nileshkumar J Patel, Varunsiri Atti, Mir B Basir, Vikas Aggarwal
No abstract text is available yet for this article.
April 11, 2019: International Journal of Cardiology
Fulvio Salvo, Stefano Franchini
No abstract text is available yet for this article.
April 11, 2019: International Journal of Cardiology
Wojciech Wańha, Maksymilian Mielczarek, Tomasz Roleder, Szymon Ładziński, Marek Milewski, Natasza Gilis-Malinowska, Michał Chmielecki, Dariusz Ciećwierz, Witold Bachorski, Piotr Kunik, Agata Trznadel, Klaudia Męcka, Alicja Genc, Rafał Januszek, Piotr Pączek, Artur Dziewierz, Stanisław Bartuś, Marcin Gruchała, Grzegorz Smolka, Dariusz Dudek, Eliano Pio Navarese, Andrzej Ochała, Miłosz Jaguszewski, Wojciech Wojakowski
BACKGROUND: Data regarding the efficacy of the percutaneous coronary intervention (PCI) with new-designed drug-eluting stent (new-DES) vs. bare metal stent (BMS) of saphenous vein grafts (SVG) stenosis is scarce. The primary objective was to compare one-year clinical outcomes of PCI in stenosis of SVG using new-DES vs. BMS in a real-world population. METHODS AND RESULTS: We carried out a multi-center registry comparing new-DES with BMS in all consecutive patients undergoing PCI of SVG...
April 11, 2019: International Journal of Cardiology
Iwan Harries, Giovanni Biglino, Anna Baritussio, Estefania De Garate, Amardeep Dastidar, Juan Carlos Plana, Chiara Bucciarelli-Ducci
BACKGROUND: Anthracycline cardiomyopathy contributes to the morbidity and mortality of cancer survivors but long-term data are lacking. This study sought to describe the phenotype of long-term anthracycline cardiomyopathy, the prevalence of myocardial fibrosis and its association with cardiac remodeling, systolic function and clinical outcomes. METHODS AND RESULTS: We undertook contrast-enhanced CMR in 81 cancer survivors at median 5 years after anthracycline (mean dose 279 SD 89 mg/m2 )...
April 10, 2019: International Journal of Cardiology
J Nicolas Lopez-Canoa, Aurora Baluja, Marinela Couselo-Seijas, Anaberta Bermudez Naveira, Laila Gonzalez-Melchor, Adriana Rozados, Luis Martínez-Sande, Javier García-Seara, X Alberte Fernandez-Lopez, A L Fernandez, Jose Ramon Gonzalez-Juanatey, Sonia Eiras, Moisés Rodriguez-Mañero
BACKGROUND: Imaging techniques have shown the association between left atrial adipose tissue (LAAT) volume and atrial fibrillation (AF) risk. PURPOSE: To analyze 1) adipokines in peripheral and atrial plasma from patients undergoing AF ablation; 2) its association with LAAT volume measured by multislice CT and 3) its predictive value for AF recurrence. METHODS: Seventy consecutive patients undergoing AF catheter ablation were screened. Blood samples were extracted from the left atrium and peripheral vein before catheter ablation...
April 10, 2019: International Journal of Cardiology
Anais Hausvater, Sivabaskari Pasupathy, Per Tornvall, Himali Gandhi, Rosanna Tavella, John Beltrame, Stefan Agewall, Christina Ekenbäck, Elin Bacsovics Brolin, Judith S Hochman, Olov Collste, Harmony R Reynolds
PURPOSE: Patients with myocardial infarction and non-obstructive coronary arteries (MINOCA) may present with or without ST-elevation (STE) on the electrocardiogram (ECG). Previous studies have shown that STE was associated with higher risk of early mortality and long-term major adverse coronary events, and that cardiac magnetic resonance imaging (CMR) can help to determine whether the cause of a MINOCA presentation is ischemic or non-ischemic. We set out to determine the relationship between STE and CMR findings in patients presenting with MINOCA...
April 10, 2019: International Journal of Cardiology
Yvonne Reinke, Stephanie Könemann, Bishwas Chamling, Stefan Gross, Kerstin Weitmann, Wolfgang Hoffmann, Karin Klingel, Matthias Nauck, Jens Fielitz, Marcus Dörr, Stephan B Felix
BACKGROUND: Cardiodepressant antibodies contribute to cardiac dysfunction in dilated cardiomyopathy (DCM). Changes in immunoglobulin G (IgG) glycosylation modulate the activity of various autoimmune diseases and influence disease activity as well as severity of various autoimmune diseases. We hypothesized that alterations in IgG glycosylation are involved in the disease course of DCM. METHODS AND RESULTS: IgG glycosylation was analyzed in plasma samples of 50 DCM patients using a lectin-based ELISA...
April 9, 2019: International Journal of Cardiology
Joanna Cwikiel, Ingebjørg Seljeflot, Morten W Fagerland, Kristian Wachtell, Harald Arnesen, Eivind Berge, Arnljot Flaa
BACKGROUND: Exercise stress test (EST) has a moderate precision for diagnosis of CAD and could potentially obtain improved accuracy if adding a reliable cardiac biomarker to the test. OBJECTIVE: We aimed to investigate resting levels and change in hs-cTnT during EST in patients with and without angiographically significant CAD. Moreover, we intended to explore the additive value of hs-cTnT to EST results in diagnosis of stable CAD. We hypothesized that hs-cTnT would be higher in CAD patients and increase diagnostic precision of EST...
April 8, 2019: International Journal of Cardiology
Hans Kossmann, Christoph Rischpler, Franziska Hanus, Stephan G Nekolla, Karl P Kunze, Katharina Götze, Alexander Goedel, Hendrik Sager, Adnan Kastrati, Daniel Sinnecker, Christian Kupatt, Tareq Ibrahim, Markus Schwaiger, Karl-Ludwig Laugwitz, Ralf J Dirschinger
The local inflammatory response following acute myocardial infarction (AMI) is increasingly being recognized as a central factor determining infarct healing. Myocardial inflammation can be visualized in patients using fasting 18 F-FDG PET/MRI. Although this novel biosignal correlates with long-term functional outcome, the corresponding cellular substrate is not well understood. Here we present a retrospective analysis of 29 patients with AMI who underwent revascularization, suggesting a connection between post infarction myocardial fasting 18 F-FDG uptake, monocyte platelet aggregates (MPA), and P2Y12 inhibition...
April 8, 2019: International Journal of Cardiology
A M C Koop, Q A J Hagdorn, G P L Bossers, T van Leusden, A Gerding, M van Weeghel, F M Vaz, D P Y Koonen, H H W Silljé, R M F Berger, B Bartelds
INTRODUCTION: Right ventricular (RV) failure due to pressure load is an important determinant of clinical outcome in pulmonary hypertension, congenital heart disease and left ventricular failure. The last decades it has become clear that metabolic dysregulation is associated with the development of RV-failure. However, underlying mechanisms remain to be unraveled. Recently, disruption of intracardiac lipid content has been suggested as potential inducer of RV failure. In the present study, we used a rat model of RV-dysfunction and aimed to obtain insight in temporal changes in RV-function, -remodelling and -metabolism and relate this to RV lipid content...
April 8, 2019: International Journal of Cardiology
Satoru Mitomo, Ozan M Demir, Sunao Nakamura
No abstract text is available yet for this article.
April 8, 2019: International Journal of Cardiology
Tadao Aikawa, Toshiyuki Nagai, Toshihisa Anzai
No abstract text is available yet for this article.
April 8, 2019: International Journal of Cardiology
Mohammed A Al-Hijji, Amir Lerman
No abstract text is available yet for this article.
April 8, 2019: International Journal of Cardiology
Kozo Okada, Yasuhiro Honda, Helen Luikart, Paul G Yock, Peter J Fitzgerald, Alan C Yeung, Hannah A Valantine, Kiran K Khush, William F Fearon
BACKGROUND: Acute allograft rejection (AAR) plays an important role in patient and graft survival; therefore, more emphasis should be placed on its prediction. This study aimed to investigate baseline clinical and diagnostic variables associated with subsequent AAR during the first year post-transplant, especially focusing on early physiologic and anatomic measures. METHODS: This study enrolled 88 heart transplant patients who underwent fractional flow reserve (FFR), coronary flow reserve (CFR), the index of microcirculatory resistance (IMR) and intravascular ultrasound (IVUS) in the left anterior descending artery at baseline (within 8 weeks post-transplant)...
April 8, 2019: International Journal of Cardiology
Jan Wintrich, Valerie Pavlicek, Felix Mahfoud, Karin Klingel, Michael Böhm, Christian Ukena, Ingrid Kindermann
No abstract text is available yet for this article.
April 5, 2019: International Journal of Cardiology
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