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International Journal of Cardiology | Page 2

Qing Qin, Shufu Chang, Rende Xu, Mingqiang Fu, Lu Chen, Lei Ge, Juying Qian, Jianying Ma, Junbo Ge
BACKGROUND: Coronary perforation is a serious complication in percutaneous coronary intervention (PCI). In this article, we reported the short and long-term outcomes of patients with coronary perforation managed by coil embolization in our center. METHODS: We retrospectively analyzed 66 patients who had coronary perforation treated by coil embolization during PCI performed in our center from Oct 2012 to June 2018. RESULTS: Of sixty-six cases of coronary perforation, twenty-six cases were distal coronary perforation, while 40 cases were collateral perforation...
August 1, 2019: International Journal of Cardiology
Takefumi Kishimori, Takeyuki Kiguchi, Kosuke Kiyohara, Tasuku Matsuyama, Haruka Shida, Chika Nishiyama, Daisuke Kobayashi, Satoe Okabayashi, Tomonari Shimamoto, Sumito Hayashida, Tetsuhisa Kitamura, Takashi Kawamura, Taku Iwami
BACKGROUND: Randomized controlled trials or observational studies showed that the use of public-access automated external defibrillator (AED) was effective for patients with out-of-hospital cardiac arrest (OHCA). However, it is unclear whether public-access AED use is effective for all patients with OHCA irrespective of first documented rhythm. We aimed to evaluate the effect of public-access AED use for OHCA patients considering first documented rhythm (shockable or non-shockable) in public locations...
August 1, 2019: International Journal of Cardiology
Jingyi Wang, Therese Tillin, Alun D Hughes, Nish Chaturvedi
BACKGROUND: The role of family history in determining excess risk of coronary heart disease (CHD) in South Asians compared with Europeans is unclear. We hypothesized that family history would be more strongly associated with CHD in South Asians. METHODS: We performed cross-sectional analyses of 20-year follow-up data from SABRE (Southall And Brent Revisited) population-based study. Initial recruitment (1988-1991) was by random selection from general practitioners' lists in north-west London...
August 1, 2019: International Journal of Cardiology
Eyal Ben-Assa, Simon Biner, Shmuel Banai, Yaron Arbel, Michal Laufer-Perl, Judith Kramarz, Sammy Elmariah, Ignacio Inglessis, Gad Keren, Ariel Finkelstein, Yan Topilsky
BACKGROUND: While the impact of mitral regurgitation (MR) prior to transcatheter aortic valve replacement (TAVR) has been intensively studied, the implications of post-procedural MR on outcome are unknown. We investigated the clinical and physiological impact of significant MR after TAVR. METHODS: Clinical and echocardiographic data of 486 patients who underwent TAVR between March 2009 and December 2014 were evaluated. Clinical endpoints included overall mortality and combined endpoint of mortality, heart failure re-hospitalization and new atrial fibrillation...
August 1, 2019: International Journal of Cardiology
Yutaka Furukawa
No abstract text is available yet for this article.
August 1, 2019: International Journal of Cardiology
Trushil G Shah, Jaini M Sutaria, Manav V Vyas
BACKGROUND: Pulmonary hypertension is associated with atrial fibrillation and paradoxical embolism. Yet, the association between pulmonary hypertension and stroke has not been well studied. METHODS: We reviewed Medline and Embase from inception to December 1, 2018, to identify observational studies reporting prevalence of stroke in adult patients with pulmonary hypertension. We sought studies that included patients with pulmonary hypertension secondary to any etiology except left heart failure, and excluded studies that reported rates of perioperative stroke...
July 31, 2019: International Journal of Cardiology
Nicola Cosentino, Jeness Campodonico, Gianluca Pontone, Marco Guglielmo, Mirella Trinei, Maria Teresa Sandri, Daniela Riggio, Andrea Baggiano, Valentina Milazzo, Marco Moltrasio, Giuseppe Muscogiuri, Alice Bonomi, Simone Barbieri, Emilio Assanelli, Gianfranco Lauri, Antonio Bartorelli, Giancarlo Marenzi
BACKGROUND: Iron deficiency (ID) is a known co-morbidity and a potential therapeutic target in heart failure. Whether ID is frequent also in ST-segment elevation acute myocardial infarction (STEMI) patients and is associated with worse in-hospital outcomes has never been evaluated. METHODS: We defined ID as a serum ferritin < 100 μg/L or transferrin saturation < 20% at hospital admission. We assessed the association between ID and the primary endpoint (a composite of in-hospital mortality and Killip class ≥ 3)...
July 31, 2019: International Journal of Cardiology
Gerhard Sulo, Jannicke Igland, Enxhela Sulo, Simon Øverland, Grace M Egeland, Stein Emil Vollset, Grethe S Tell
BACKGROUND: Trends on cause-specific mortality following acute myocardial infarction (AMI) are poorly described and no studies have analyzed where do AMI patients die. We analyzed trends in 28-day and one-year mortality following an incident AMI with focus on changes over time in the underlying cause and place of death. METHODS: We identified in the 'Cardiovascular Disease in Norway' Project all patients 25+ years, hospitalized with an incident AMI in Norway, 2001-2014...
July 31, 2019: International Journal of Cardiology
Wei Qin, Longyin Zhang, Zhange Li, Dan Xiao, Yue Zhang, Huan Yang, Xin Liu, Haiying Zhang, Xiaohui Chen, Chaoqian Xu, Baofeng Yang, Yong Zhang
BACKGROUND: Vascular aging has profound effects on cardiovascular diseases. Endothelial to mesenchymal transition (EndMT) is defined as the acquisition of mesenchymal characteristics by endothelial cells (ECs) and has been found induced in a model of ECs aging. However, whether EndMT occurs during aging in vivo, the functional significance of EndMT on vascular biology and the underlying mechanisms remain unknown. METHODS AND RESULTS: In this study, we examined the vascular ECs from young (2 months old) and old (18 months old) mice, and demonstrated that aged ECs underwent EndMT...
July 30, 2019: International Journal of Cardiology
Stein Ove Danielsen, Philip Moons, Leiv Sandvik, Marit Leegaard, Svein Solheim, Theis Tønnessen, Irene Lie
BACKGROUND: Thirty-day all-cause readmissions are high after aortic valve replacement (AVR). We aimed to assess the effectiveness of a structured telephone follow-up (TFU) and a 24/7 hotline on reducing 30-day all-cause readmission (30-DACR) after AVR, on reducing symptoms of anxiety and depression and on improving perceived health state. METHODS: A prospective randomized controlled trial was conducted. Patients (n = 288) were randomly allocated to either post-discharge usual care or to care that provided TFU and access to a 24/7 hotline after AVR...
July 30, 2019: International Journal of Cardiology
Maria A Baturova, Kristina H Haugaa, Henrik K Jensen, Anneli Svensson, Thomas Gilljam, Henning Bundgaard, Trine Madsen, Jim Hansen, Monica Chivulescu, Morten Krogh Christiansen, Jonas Carlson, Thor Edvardsen, Jesper H Svendsen, Pyotr G Platonov
BACKGROUND: Recent studies in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients have drawn attention to atrial fibrillation (AF) as an arrhythmic manifestation of ARVC and as an indicator of atrial involvement in the disease progression. We aimed to assess the prevalence of AF in the Scandinavian cohort of ARVC patients and to evaluate its association with disease clinical manifestations. METHODS: Study sample comprised of 293 definite ARVC patients by 2010 Task Force criteria (TFC2010) and 141 genotype-positive family members (total n = 434, 43% females, median age at ARVC diagnosis 41 years [interquartile range (IQR) 28-52 years])...
July 30, 2019: International Journal of Cardiology
Babu Muhamed, Daniel Mutithu, Olukayode Aremu, Liesl Zühlke, Karen Sliwa
In recent years, the devastating effect of rheumatic fever (RF) and rheumatic heart disease (RHD) in Africa has been acknowledged by Institutions such as the Pan-African Society of Cardiology, the African Union Commission, and the World Health Organization. Key priorities set to eradicate RF and RHD include diagnosing and managing RF and RHD, building registries, improving adequate supplies of benzathine penicillin, reproductive health services, and cardiac surgery, developing multi-sectoral RHD awareness programmes, understanding RHD pathogenesis and fostering international partnership for resource mobilization...
July 29, 2019: International Journal of Cardiology
Fadi Al-Rashid, Matthias Totzeck, Amir A Mahabadi, Laura Johannsen, Peter Luedike, Alexander Lind, Andrea Krueger, Markus Kamler, Philipp Kahlert, Rolf Alexander Jánosi, Gerd Heusch, Tienush Rassaf
BACKGROUND: Patients with severe coronary artery disease (CAD), comorbidities, or impaired hemodynamics are at risk during percutaneous coronary interventions. The aim of the study was to investigate the safety and efficacy of a novel risk-stratification algorithm for high-risk coronary procedures. METHODS AND RESULTS: We prospectively screened 1189 patients with CAD requiring revascularization (period 07/2017-06/2018). The algorithm was designed to select high-risk procedures...
July 29, 2019: International Journal of Cardiology
Dongzhi Wang, Hailing Li, E Kenneth Weir, Yawei Xu, Dachun Xu, Yingjie Chen
Patients with pulmonary arterial hypertension (PAH) and right ventricular (RV) failure have a poor clinical outcome, but the mechanisms of PAH and RV failure development are not totally clear. PAH is associated with reduced NO bioavailability and increased endogenous NOS inhibitor asymmetric dimethylarginine (ADMA). Dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays a critical role in ADMA degradation. Here we generated a novel DDAH1 deficiency rat strain using the CRISPR-Cas9 technique, and studied the effect of DDAH1 dysfunction on monocrotaline-induced PAH, lung vascular remodeling and RV hypertrophy...
July 27, 2019: International Journal of Cardiology
Shemy Carasso, Dalit Porat Ben Amy, Fabio Kusniec, Diab Ghanim, Doron Sudarsky, Wadi Kinany, Chen Shmuel, Imad Abu El-Naaj, Erez Kachel, Offer Amir
BACKGROUND: 40% of cases of infective endocarditis (IE) are likely caused by oral bacteria. IE prevalence after transcatheter aortic valve replacement (TAVR) is comparable to IE following surgical prosthetic valve replacement (SVR). Current guidelines recommend pre-operative dental screening for SVR, without specific recommendations regarding TAVR. We aimed to compare oral dental findings in TAVR vs. surgical valve replacement (SVR) candidates and assess the need for routine dental screening and treatment prior to TAVR similar to the SVR patients...
July 26, 2019: International Journal of Cardiology
Kari Feldt, Rodney De Palma, Henrik Bjursten, Petur Petursson, Niels Erik Nielsen, Thomas Kellerth, Anders Jönsson, Johan Nilsson, Andreas Rück, Magnus Settergren
BACKGROUND: The impact of a change in mitral regurgitation (MR) following TAVR is unknown. We studied the impact of baseline MR and early post-procedural change in MR on survival following TAVR. METHODS: The SWEDEHEART registry included all TAVRs performed in Sweden. Patients were dichotomized into no/mild and moderate/severe MR groups. Vital status, echocardiographic data at baseline and within 7 days after TAVR were analyzed. RESULTS: 1712 patients were included...
July 24, 2019: International Journal of Cardiology
Alberto Zanatta, Elisa Carturan, Stefania Rizzo, Cristina Basso, Gaetano Thiene
Myocarditis was discovered as heart disease at autopsy with the use of microscope. In 1900, with the name of acute interstitial myocarditis, Carl Ludwig Alfred Fiedler first reported the history of a sudden cardiac heart failure, in the absence of coronary, valve, pericardial disease or classical specific infections with multiorgan involvement. He postulated a peculiar isolated acute inflammation of the myocardium with poor prognosis due to invisible microorganisms, which years later would have been identified as viruses...
July 24, 2019: International Journal of Cardiology
Zachary L Cox, Pikki Lai, Connie M Lewis, JoAnn Lindenfeld
BACKGROUND: Admission blood glucose (BG) has demonstrated contradictory association with 30-day mortality in acute heart failure (AHF) hospitalization. To explore these contradictory findings, we aimed to determine if admission BG reflects an acute change from chronic glucose control and investigate the association between the admission and chronic BG change (ΔBG) with 30-day mortality in AHF. METHODS: We analyzed patients (n = 1045) age ≥ 65 with Centers of Medicare Services benefits and known 30-day all-cause mortality hospitalized with AHF at an academic medical center from 2009 to 2016...
July 23, 2019: International Journal of Cardiology
Tariq Ashraf, Muhammad Nauman Khan, Syed Muhammad Afaque, Kanwal Fatima Aamir, Mukesh Kumar, Tahir Saghir, Syed Ishtiaq Rasool, Syed Nadeem Hassan Rizvi, Jawaid Akbar Sial, Asif Nadeem, Abid Amin Khan, Musa Karim
OBJECTIVES: In the present study, we analysed the incidence of no-reflow phenomenon, its clinical and procedural predictors, and associated in-hospital outcomes for the patients undergoing primary percutaneous coronary intervention (PCI). BACKGROUND: No-reflow phenomenon after primary PCI is a procedural complication associated with adverse post-procedure outcomes. METHODS: Data for this study were extracted from global registry, NCDR®, the site of National Institute of Cardiovascular Disease (NICVD), Karachi from July 2017 to March 2018...
July 23, 2019: International Journal of Cardiology
Elena Critselis, Demosthenes B Panagiotakos, Ekavi N Georgousopoulou, Paraskevi Katsaounou, Christina Chrysohoou, Christos Pitsavos
BACKGROUND: Despite WHO Framework Convention of Tobacco Control (FCTC) adoption, effective implementation of national smoking bans remains pending in several countries. This study quantified the association of second hand smoke (SHS) exposure and 10-year cardiovascular disease (CVD) among never smokers in such settings. METHODS: In 2001-2002, a sample of 1514 males and 1528 females (range: 18-89 years old) were randomly selected in Greece. Frequency and duration of SHS exposure (i...
July 23, 2019: International Journal of Cardiology
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