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International Endodontic Journal

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https://read.qxmd.com/read/30773661/micro-ct-evaluation-of-sonically-and-ultrasonically-activated-irrigation-on-the-removal-of-hard-tissue-debris-from-isthmus-containing-mesial-root-canal-systems-of-mandibular-molars
#1
T Rödig, C Koberg, S Baxter, F Konietschke, A Wiegand, M Rizk
AIM: To evaluate the efficacy of sonically and ultrasonically activated irrigation on removal of accumulated hard-tissue debris (AHTD) in mesial root canal systems of mandibular molars using micro-computed tomographic (micro-CT) analysis. METHODOLOGY: Forty mesial roots of mandibular molars with two independent canals joint apically by an isthmus (Vertucci type II) were selected, root canals were instrumented using Reciproc R25 instruments and specimens were scanned at a resolution of 10...
February 18, 2019: International Endodontic Journal
https://read.qxmd.com/read/30761555/effect-of-tissue-inhibitor-of-metalloprotease-1-on-human-pulp-cells-in-vitro-and-rat-pulp-tissue-in-vivo
#2
M Okamoto, Y Takahashi, S Komichi, M Ali, M Watanabe, M Hayashi
AIM: To evaluate the dentinogenetic effects of tissue inhibitor of metalloprotease (TIMP1) on human pulp cells in vitro and rat pulp tissue in vivo. METHODOLOGY: The effect of TIMP1 on pulp cell functions related to hard tissue formation as part of the wound healing process (i.e. biocompatibility, proliferation, differentiation and mineralized nodule formation) was evaluated in vitro and using a direct pulp capping experimental animal model in vivo. The effects of different-sized cavity preparations on hard tissue formation induced by ProRoot MTA at 2 weeks were evaluated using micro-computed tomography (micro-CT)...
February 13, 2019: International Endodontic Journal
https://read.qxmd.com/read/30758848/2d-and-3d-radiographic-outcome-assessment-of-the-effect-of-guided-tissue-regeneration-using-resorbable-collagen-membrane-in-the-healing-of-through-and-through-periapical-lesions-a-randomized-controlled-trial
#3
P D Parmar, R Dhamija, S Tewari, P Sangwan, A Gupta, J Duhan, S Mittal
AIM: To evaluate the effect of collagen membrane on the healing of through-and-through periapical lesions using 2-dimensional (2D) and 3-dimensional (3D) imaging techniques. METHODOLOGY: Thirty two patients with periapical radiolucencies measuring at least 10mm and with confirmed loss of buccal and lingual cortical plates were randomly divided into GTR and control groups. Periapical surgery was performed in both groups, using a resorbable collagen membrane in GTR group only...
February 13, 2019: International Endodontic Journal
https://read.qxmd.com/read/30756431/maternal-apical-periodontitis-is-associated-with-insulin-resistance-in-adult-offspring
#4
T V S Tsosura, F Y Chiba, M S L C Mattera, R F Pereira, L T A Cintra, L C Conti, R M Dos Santos, J H P Mateus, C A S Garbin, D H Sumida
AIM: To investigate the plasma concentrations of glucose, insulin, and tumour necrosis factor-α (TNF-α) of rats with maternal apical periodontitis (AP) and to explore the effect of maternal inflammation on the initial steps of insulin signaling and the inflammatory pathway in the gastrocnemius muscle (GM) and periepididymal white adipose tissue (pWAT) of adult offspring. METHODOLOGY: Fifteen female Wistar rats were distributed into a control group (CN), a group with 1 AP (1AP) and group with 4 AP (4AP)...
February 12, 2019: International Endodontic Journal
https://read.qxmd.com/read/30734930/micro-ct-analysis-of-chronic-apical-periodontitis-induced-by-several-specific-pathogens
#5
S Chen, H Lei, Y Luo, S Jiang, M Zhang, H Lv, Z Cai, X Huang
AIM: To conduct three dimensional micro-CT analysis of bone destruction, periapical sclerotic changes and inflammatory root resorption (IRR) to compare the differences between Enterococcus faecalis (Ef)- and Porphyromonas gingivalis (Pg)-induced chronic apical periodontitis (CAP). METHODOLOGY: Mono-species bacteria induced CAP was established in the first and second molars of the right maxilla and mandible of male Sprague-Dawley rats. Fifteen animals were divided into three groups with 5 rats in each group: control group, Ef-CAP group, Pg-CAP group...
February 8, 2019: International Endodontic Journal
https://read.qxmd.com/read/30720875/antimicrobial-action-of-photodynamic-therapy-in-root-canals-using-led-curing-light-curcumin-and-carbopol-gel
#6
D F Oda, M A H Duarte, F B Andrade, L T Moriyama, V S Bagnato, I G de Moraes
AIM: To evaluate the capacity of carbopol gel to maintain the intensity of a LED curing light (blueLED) along the length of prepared root canals in bovine teeth, and to assess the antimicrobial capacity of curcumin photoactivated by a LED curing light in the presence of carbopol gel. METHODOLOGY: Experiment 1: Eight straight roots of bovine incisors were standardized to a length of 15 mm, and the root canals instrumented up to a size 120 K-file. The LED curing light was irradiated inside the root canals using an aluminium collimator (1...
February 5, 2019: International Endodontic Journal
https://read.qxmd.com/read/30719720/inflammatory-potential-of-monospecies-biofilm-matrix-components
#7
T Ramirez, A Shrestha, A Kishen
AIM: To assess the inflammatory potential of biofilm matrix constituents of Enterococcus faecalis and Pseudomonas aeruginosa monospecies biofilms on macrophages. METHODOLOGY: In vitro biofilms of E. faecalis and P. aeruginosa were grown (7 days) in aerobic and anaerobic conditions. The biofilm matrix components: exopolysaccharides (EPS) and extracellular DNA (eDNA) were extracted and quantified. The inflammatory potential of EPS and eDNA were assessed on macrophage cell lines (RAW 267...
February 5, 2019: International Endodontic Journal
https://read.qxmd.com/read/30715732/micro-ct-evaluation-of-the-removal-of-root-fillings-using-the-protaper-universal-retreatment-system-supplemented-by-the-xp-endo-finisher-file
#8
H Aksel, S Küçükkaya Eren, S Askerbeyli Örs, A Serper, M Ocak, H H Çelik
AIM: To compare the removal of root fillings using the ProTaper Universal Retreatment system (PTUR) followed by a supplementary preparation with the XP-Endo Finisher file. METHODOLOGY: The mesiobuccal root canals of 30 mandibular first molars were instrumented with ProTaper Universal NiTi files up to F2 and filled with one of the following sealers using a single-cone technique (n=10); AH Plus, NeoMTA Plus and Endosequence BC. The root fillings were removed using the PTUR system with additional apical preparation using ProTaper F2 and F3 files...
February 4, 2019: International Endodontic Journal
https://read.qxmd.com/read/30712265/nlrp6-suppresses-the-inflammatory-response-of-human-periodontal-ligament-cells-by-inhibiting-nf-%C3%AE%C2%BAb-and-erk-signal-pathways
#9
W L Lu, L Zhang, D Z Song, X W Yi, W Z Xu, L Ye, D M Huang
AIM: To explore the function and mechanisms of NLRP6 (NOD-, LRR- and pyrin domain-containing 6) in the inflammatory response of human periodontal ligament cells (HPDLCs). METHODOLOGY: Apical periodontitis tissues were obtained from 3 patients who received endodontic microsurgery. The expression of NLRP6 in 3 human apical periodontitis tissues and HPDLCs was examined by immunohistochemistry and immunofluorescence, respectively. The expressions of NLRP6, Phospho(p)- p65, p65, IκB-α, p- IκB-α, ERK, p- ERK, NLRP3, Pro interleukin (IL)-1β, Pro caspase-1 and apoptosis-associated speck-like protein containing a CARD (ASC) were examined by western blot...
February 3, 2019: International Endodontic Journal
https://read.qxmd.com/read/30706491/how-is-endodontics-taught-a-survey-to-evaluate-undergraduate-endodontic-teaching-in-dental-schools-within-the-united-kingdom
#10
H Alraisi, P M H Dummer, M E Vianna
AIM: To evaluate the delivery of undergraduate endodontic education in UK dental schools using an online survey and to compare the results with those of a previous paper-based survey (Qualtrough & Dummer 1997). Aspects of delivery were also evaluated in comparison with Undergraduate Curriculum Guidelines of the European Society of Endodontology (de Moor et al. 2013). METHODS: An online version of an earlier paper-based survey on undergraduate Endodontic education (Qualtrough & Dummer 1997) was created...
January 31, 2019: International Endodontic Journal
https://read.qxmd.com/read/30703248/effects-of-triethylene-glycol-dimethacrylate-and-hydroxyethyl-methacrylate-on-macrophage-polarization
#11
I-S Kim, H C Park, H Quan, Y Kim, L Wu, H-C Yang
AIM: To evaluate the effects of hydrophilic dental resin monomers, triethylene glycol dimethacrylate (TEGDMA) and hydroxyethyl methacrylate (HEMA), on the polarization of a human monocyte cell line (THP-1). METHODOLOGY: THP-1 cells were treated with resin monomers at non-cytotoxic concentrations for 48 h and were analyzed for CD86 and CD206 expressions using flow cytometry. The cells were stimulated for polarization in the presence of resin monomers (co-treatment), or after treatment with monomers (pre-treatment)...
January 31, 2019: International Endodontic Journal
https://read.qxmd.com/read/30702145/cytocompatibility-bioactive-potential-and-antimicrobial-activity-of-an-experimental-calcium-silicate-based-endodontic-sealer
#12
C L Zordan-Bronzel, M Tanomaru-Filho, E M Rodrigues, G M Chávez-Andrade, G Faria, J M Guerreiro-Tanomaru
AIM: To evaluate the cytocompatibility, bioactive potential, antimicrobial and antibiofilm activities of an experimental calcium silicate-based endodontic sealer, in comparison with TotalFill BC Sealer and AH Plus. METHODOLOGY: Cytocompatibility was assessed by methyltetrazolium (MTT) and neutral red (NR) assays, after exposure of the Saos-2 cells to the sealer extracts (1 : 2, 1 : 4, 1 : 8, 1 : 16 and 1 : 32 dilutions) for 24 h. The sealers were manipulated and placed in 12-well culture plates and exposed to ultraviolet light; then, 5 mL of DMEM without serum was added...
January 31, 2019: International Endodontic Journal
https://read.qxmd.com/read/30702139/preferred-reporting-items-for-randomized-trials-in-endodontics-prirate-guidelines-a-development-protocol
#13
REVIEW
V Nagendrababu, H F Duncan, L Bjørndal, T Kvist, E Priya, S J Pulikkotil, J Jayaraman, P M H Dummer
Randomized clinical trials are acknowledged as the most appropriate methodology for demonstrating the efficacy or effectiveness of one intervention as opposed to another and thus play a major role in clinical decision making. However, it is recognized that despite the existence of various guidelines, for example, the Consolidated Standards for Reporting Trials (CONSORT) statement, the quality of manuscripts describing randomised trials is often suboptimal. The current project aims to develop and disseminate new guidelines, Preferred Reporting Items for RAndomized Trials in Endodontics (PRIRATE), to improve the planning and reporting quality of randomized trials in the field of Endodontics...
January 31, 2019: International Endodontic Journal
https://read.qxmd.com/read/30697770/bovine-teeth-can-reliably-substitute-human-dentine-in-an-intra-tooth-push-out-bond-strength-model
#14
E J N L Silva, N K Carvalho, M C Prado, P M Senna, E M Souza, G De-Deus
AIM: To investigate the reliability of using bovine teeth as an alternative to human teeth in an intra-tooth push-out model by comparing the bond strength of three root canal sealers in both tooth substrates. METHODOLOGY: From human and bovine incisors (12 per group), one 1-mm disc was obtained from each root. On each disc, three standard 0.8mm-diameter holes were drilled through the dentine. After irrigation, the holes were filled with one of the three tested root canal sealers: AH Plus, MTA Fillapex or Total Fill BC Sealer...
January 29, 2019: International Endodontic Journal
https://read.qxmd.com/read/30688377/micro-computed-tomographic-evaluation-of-shaping-ability-of-four-instrumentation-systems-in-curved-root-canals
#15
C P Stringheta, C E S Bueno, A S Kato, L G Freire, E F Iglecias, M Santos, R A Pelegrine
AIM: To compare the shaping ability of four instrumentation systems in curved molar root canals, using computerized microtomography (micro-CT). METHODOLOGY: Forty mesial roots of mandibular molars were submitted first to radiographic examination to determine their curvature, and then to a micro-CT scan to analyze other initial morphological characteristics. The specimens were distributed into 4 experimental groups, according to the endodontic instrumentation system used (n = 10): Group R, Reciproc; Group PTN, ProTaper Next; Group WOG, WaveOne Gold; Group PDL, ProDesign Logic...
January 28, 2019: International Endodontic Journal
https://read.qxmd.com/read/30667524/the-top-50-most-cited-articles-published-in-the-international-endodontic-journal
#16
P Ahmad, P M H Dummer, T Y Noorani, J A Asif
AIM: To analyze the main characteristics of the top 50 most-cited articles published in the International Endodontic Journal from 1967 to 2018. METHODOLOGY: The Clarivate Analytics' Web of Science "All Databases", Elsevier's Scopus, Google Scholar and PubMed Central were searched to retrieve the 50 most-cited articles in the IEJ published from April 1967 to December 2018. The articles were analyzed and information including number of citations, year of publication, contributing authors, institutions and countries, study design, study topic, impact factor, and keywords was extracted...
January 22, 2019: International Endodontic Journal
https://read.qxmd.com/read/30667519/endodontics-and-diabetes-association-versus-causation
#17
REVIEW
J J Segura-Egea, D Cabanillas-Balsera, M C Jiménez-Sánchez, J Martín-González
Endodontic medicine has gained more attention and is becoming a more important issue in Endodontics. As an example, more than one hundred articles on this topic have been published in the last eight years. Several of these studies have found an association between endodontic variables, i.e. the prevalence of apical periodontitis, the prevalence of root canal treatment (RCT) and the outcome of RCT assessed as root filled teeth (RFT) with radiolucent periapical lesions (RPL) or non-retained RFT, and several systemic diseases, such as diabetes, cardiovascular disease, smoking habits, osteoporosis, inherited coagulopaties, biologic medications, low birth weigth or physical fitness...
January 22, 2019: International Endodontic Journal
https://read.qxmd.com/read/30664240/european-society-of-endodontology-position-statement-management-of-deep-caries-and-the-exposed-pulp
#18
H F Duncan, K M Galler, P L Tomson, S Simon, I El-Karim, R Kundzina, G Krastl, T Dammaschke, H Fransson, M Markvart, M Zehnder, L Bjørndal, P M H Dummer
This position statement on the management of deep caries and the exposed pulp represents the consensus of an expert committee, convened by the European Society of Endodontology (ESE). Preserving the pulp in a healthy state with sustained vitality, preventing apical periodontitis and developing minimally invasive biologically based therapies are key themes within contemporary clinical endodontics. The aim of this statement is to summarise current best evidence on the diagnosis and classification of deep caries and caries-induced pulpal disease, as well as indicating appropriate clinical management strategies for avoiding and treating pulp exposure in permanent teeth with deep or extremely deep caries...
January 21, 2019: International Endodontic Journal
https://read.qxmd.com/read/30663790/xp-endo-finisher-r-instrument-optimizes-the-removal-of-root-filling-remnants-in-oval-shaped-canals
#19
G De-Deus, F G Belladonna, A S Zuolo, D M Cavalcante, J C A Carvalhal, M S Carvalho, E M Souza, R T Lopes, E J N L Silva
AIM: To evaluate the performance of XP-endo Finisher R instruments when removing root filling remnants from oval-shaped canals using micro-computed tomographic (micro-CT) imaging as the analytical tool. Passive ultrasonic irrigation (PUI) was used as a reference technique for comparison. METHODOLOGY: Twenty mandibular incisors with oval-shaped canals were matched based on similar anatomic features of the canal (volume, aspect ratio and 3D configuration) after scanning procedures...
January 21, 2019: International Endodontic Journal
https://read.qxmd.com/read/30661246/accuracy-of-detecting-vertical-root-fractures-in-non-root-filled-teeth-using-cone-beam-computed-tomography-effect-of-voxel-size-and-fracture-width
#20
X L Guo, G Li, J Q Zheng, R H Ma, F C Liu, F S Yuan, P J Lyu, Y J Guo, S Yin
AIM: To investigate simultaneously the effect of voxel size and fracture width on the accuracy of detecting vertical root fractures (VRF) in non-root filled teeth when using cone beam computed tomography. METHODOLOGY: Fifty-one of 161 extracted human permanent teeth (16 anterior teeth, 132 premolars, 13 mandibular molars) were selected randomly for VRF induction with two fracture widths. All teeth were scanned with four CBCT units at different voxel sizes provided by the units...
January 20, 2019: International Endodontic Journal
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