American Journal of Veterinary Research | Page 2

Neringa Alisauskaite, Thomas Bitterli, Patrick R Kircher, Antonio Pozzi, Guy C M Grinwis, Frank Steffen, Lucas A Smolders
OBJECTIVE: To evaluate agreement in results obtained with an MRI-based grading scheme and a macroscopic observation-based grading scheme when used to assess intervertebral disk (IVD) degeneration in cats. SAMPLE: 241 MRI and 143 macroscopic images of singular IVDs in 44 client-owned cats (40 cadaveric and 4 live). PROCEDURES: Singular images of IVDs were obtained of live cats admitted for treatment of suspected neurologic disease (MRI images of IVDs) and of cadavers of cats euthanized for reasons unrelated to spinal disease (MRI and macroscopic images of IVDs) at the Small Animal Hospital, Vetsuisse Faculty, Zurich, Switzerland, between January 12, 2015, and October 19, 2015...
April 2020: American Journal of Veterinary Research
(no author information available yet)
No abstract text is available yet for this article.
April 2020: American Journal of Veterinary Research
Barbara Ambros, Heather K Knych, Miranda J Sadar
OBJECTIVE: To determine the pharmacokinetics of hydromorphone hydrochloride after IV and IM administration in guinea pigs ( Cavia porcellus ). ANIMALS: 8 healthy adult guinea pigs (4 sexually intact females and 4 sexually intact males). PROCEDURES: In a crossover study, hydromorphone (0.3 mg/kg) was administered once IM (epaxial musculature) or IV (cephalic catheter) to each guinea pig at a 1-week interval (2 treatments/guinea pig). Blood samples were collected before and at predetermined intervals after drug administration via a vascular access port...
April 2020: American Journal of Veterinary Research
Carlos R Sanchez, Lee-Ann C Hayek, Ellen P Carlin, Scott A Brown, Scott Citino, Laurie Marker, Krista L Jones, Suzan Murray
OBJECTIVE: To establish a reference interval for glomerular filtration rate (GFR) determined by measuring serum clearance of a single IV dose of inulin in clinically normal cheetahs ( Acinonyx jubatus ) and compare serum symmetric dimethylarginine (SDMA) concentration in cheetahs with GFR. ANIMALS: 33 cheetahs housed at 3 institutions. PROCEDURES: A single bolus of inulin (3,000 mg/m2 ) was administered IV, and 5 serial blood samples were collected and analyzed for serum inulin concentration with the anthrone technique...
April 2020: American Journal of Veterinary Research
(no author information available yet)
No abstract text is available yet for this article.
April 2020: American Journal of Veterinary Research
Vilhelmiina Huuskonen, Flavia Restitutti, Juhana M Honkavaara, Marja R Raekallio, Sofia Männikkö, Mika Scheinin, Outi M Vainio
OBJECTIVE: To determine whether concurrent vatinoxan administration affects the antinociceptive efficacy of medetomidine in dogs at doses that provide circulating dexmedetomidine concentrations similar to those produced by medetomidine alone. ANIMALS: 8 healthy Beagles. PROCEDURES: Dogs received 3 IV treatments in a randomized crossover-design trial with a 2-week washout period between experiments (medetomidine [20 μg/kg], medetomidine [20 μg/kg] and vatinoxan [400 μg/kg], and medetomidine [40 μg/kg] and vatinoxan [800 μg/kg]; M20, M20V400, and M40V800, respectively)...
April 2020: American Journal of Veterinary Research
Mireille Godbout, Amandine Vargas, Pierre Hélie, Michela Bullone, Jean-Pierre Lavoie
OBJECTIVE: To use a biopolymer delivery system to investigate the ability of interleukin (IL)-4 to recruit neutrophils into subcutaneous tissues of equids. ANIMALS: 16 horses and 2 ponies. PROCEDURES: Animals were assigned to 3 experiments (6/experiment). Effects of recombinant equine (Req) IL-4 (100, 250, or 500 ng/site) versus a positive control (ReqIL-8; 100 ng, 250 ng, or 1 μg/site) and a negative control (Dulbecco PBSS or culture medium) on neutrophil chemotaxis were assessed after SC injection into the neck with an injectable biopolymer used as the vehicle...
April 2020: American Journal of Veterinary Research
Momoko Narita, Hidetaka Nishida, Ryota Asahina, Kohei Nakata, Hirohito Yano, Peter J Dickinson, Toshiyuki Tanaka, Hideo Akiyoshi, Sadatoshi Maeda, Hiroaki Kamishina
OBJECTIVE: To measure expression of microRNAs (miRNAs) in plasma and in extracellular vesicles (EVs) derived from plasma for dogs with glioma and dogs with other brain diseases. SAMPLE: Plasma samples from 11 dogs with glioma and 19 control dogs with various other brain diseases. PROCEDURES: EVs were isolated from plasma samples by means of ultracentrifugation. Expression of 4 candidate reference miRNAs (let-7a, miR-16, miR-26a, and miR-103) and 4 candidate target miRNAs (miR-15b, miR-21, miR-155, and miR-342-3p) was quantified with reverse transcription PCR assays...
April 2020: American Journal of Veterinary Research
Hirofumi Tanoue, Rika Uchiyama, Hideyuki Fukuda, Tom Ichinohe, Nobuo Kanno, Shuji Suzuki, Yasuji Harada, Yasushi Hara
OBJECTIVE: To investigate the effects of intervertebral distraction screw (IDS) fixation of the lumbosacral joint (LSJ) on the intervertebral foraminal area (IFA) and intervertebral stabilization of the LSJ and adjacent lumbar segments in dogs. ANIMALS: 7 healthy Beagles. PROCEDURES: Dorsal laminectomy was performed at the LSJ in each dog to expose the intervertebral disk. The IDS was then inserted into the L7-S1 disk. Computed tomography was performed before and after laminectomy and after IDS insertion (intact, laminectomy, and IDS conditions, respectively) to measure the intervertebral range of motion (ROM) and intervertebral distance (ID) at L7-S1, L6-7, and L5-6 with the LSJ in a flexed and extended position...
April 2020: American Journal of Veterinary Research
Kate P Sharon, Caryn M Thompson, B Duncan X Lascelles, Rudolph S Parrish
OBJECTIVE: To develop methods to identify and characterize activity monitor (AM) data signatures for jumps performed by cats. ANIMALS: 13 healthy, client-owned cats without evidence of osteoarthritis or degenerative joint disease. PROCEDURES: Each cat was fitted with the same AM, individually placed in an observation room, then simultaneously recorded by 3 video cameras during the observation period (5 to 8 hours). Each cat was encouraged to jump up (JU), jump down (JD), and jump across (JA) during the observation period...
April 2020: American Journal of Veterinary Research
Ian C Simcock, J Ciaran Hutchinson, Susan C Shelmerdine, Jose Novos Matos, Neil J Sebire, Virginia Luis Fuentes, Owen J Arthurs
OBJECTIVE: To determine optimal sample preparation conditions with potassium triiodide (I2 KI) and optimal imaging settings for microfocus CT (micro-CT) of excised cat hearts. SAMPLE: 7 excised hearts (weight range, 10 to 17.6 g) obtained from healthy adult cats after euthanasia by IV injection of pentobarbital sodium. PROCEDURES: Following excision, the hearts were preserved in 10% formaldehyde solution. Six hearts were immersed in 1.25% I2 KI solution (n = 3) or 2...
April 2020: American Journal of Veterinary Research
Rebecca L Tinklenberg, Shane D Murphy, Jonathan P Mochel, Yeon-Jung Seo, Alyssa L Mahaffey, Yuqi Yan, Jessica L Ward
OBJECTIVE: To determine whether a dose-response relationship exists between short-term oral prednisone administration and common clinicopathologic variables, cardiovascular biomarkers, and systolic arterial blood pressure (SAP) in healthy dogs. ANIMALS: 8 healthy Beagles. PROCEDURES: Dogs underwent five 5-day experiments (no prednisone treatment [control condition] and prednisone administration at 0.5, 1, 2, and 4 mg/kg, PO, q 24 h), with a 9-day washout period between protocols...
April 2020: American Journal of Veterinary Research
Yasutomo Hori, Yohei Yamashita, Keiichiro Sakakibara, Tadashi Sano, Ai Hori
OBJECTIVE: To investigate whether lung ultrasonography (LUS) performed around the heart, where the lungs are in contact with the pericardium (ie, pericardial LUS), could be used for the diagnosis of cardiogenic pulmonary edema (CPE) in dogs with degenerative mitral valve disease (DMVD). ANIMALS: 15 control dogs with healthy hearts and 26 dogs with DMVD. PROCEDURES: In a prospective multicenter study design, dogs with DMVD were assigned to 2 groups: those with CPE (n = 11) and those without CPE (15)...
March 2020: American Journal of Veterinary Research
Michael J Yaeger, Zuowei Wu, Paul J Plummer, Orhan Sahin, Melda Meral Ocal, Ashenafi F Beyi, Changyun Xu, Qijing Zhang, Ronald W Griffith
OBJECTIVE: To evaluate the efficacy of tulathromycin for prevention of abortion in pregnant ewes when administered within 24 hours after experimental inoculation with Campylobacter jejuni. ANIMALS: 20 pregnant ewes between 72 and 92 days of gestation. PROCEDURES: All ewes were inoculated with a field strain of C jejuni (8.5 × 108 to 10.6 × 108 CFUs, IV). Eighteen hours later, ewes received either tulathromycin (1.1 mL/45 kg [2.4 mg/kg], SC; n = 10) or sterile saline (0...
March 2020: American Journal of Veterinary Research
Samuel Frei, David Sanchez-Migallon Guzman, Philip H Kass, Michelle A Giuffrida, Philipp D Mayhew
OBJECTIVE: To compare a ventral and a left lateral endoscopic approach to coelioscopy in bearded dragons ( Pogona vitticeps ). ANIMALS: 18 adult bearded dragons. PROCEDURES: In a randomized crossover design involving 2 surgical approaches, anesthetized bearded dragons first underwent coelioscopy with a ventral approach (left lateral of midline next to the umbilicus; animal positioned in dorsal recumbency) or left lateral approach (intercostal; animal positioned in right lateral recumbency) and then with the alternate approach...
March 2020: American Journal of Veterinary Research
(no author information available yet)
No abstract text is available yet for this article.
March 2020: American Journal of Veterinary Research
Alyssa B Word, P Rand Broadway, Nicole C Burdick Sanchez, John P Hutcheson, Guy B Ellis, Ben P Holland, Michael A Ballou, Jeffery A Carroll
OBJECTIVE: To quantify acute immunologic and metabolic responses of beef heifers following topical administration of transdermal flunixin meglumine (TDFM) at various times relative to bovine herpesvirus 1 (BHV1) and Mannheimia haemolytica challenges. ANIMALS: 32 beef heifers (mean body weight, 170 kg). PROCEDURES: Heifers were assigned to 1 of 4 groups. Heifers in the control group did not receive TDFM, whereas 1 dose of TDFM (3.3 mg/kg) was topically applied to heifers of groups A, V, and B at -144, -72, and 0 hours...
March 2020: American Journal of Veterinary Research
Timothy L Foutz, Steven C Budsberg
OBJECTIVE: To develop a 3-D kinematic model to measure truncal motion in dogs and assess changes in truncal motion in dogs when wearing each of 2 service vests. ANIMALS: 5 adult mixed-breed dogs. PROCEDURES: 27 reflective markers were placed on the pelvis, trunk, and scapula of each dog. Six infrared cameras were placed around a treadmill to track the location of the markers within a calibrated space. Dogs were recorded during walking and trotting on the treadmill...
March 2020: American Journal of Veterinary Research
Elin J Rgensen, Freja B Hjerpe, Hans P Hougen, Thomas Bjarnsholt, Lise C Berg, Stine Jacobsen
OBJECTIVE: To evaluate histologic changes and gene expression patterns in body and limb wounds in horses in response to bacterial inoculation. SAMPLE: Wound biopsy specimens from 6 horses collected on days 7, 14, 21, and 27 after excisional wounds (20 wounds/horse) were created over the metacarpal and metatarsal region and lateral thoracic region (body) and then inoculated or not inoculated on day 4 with Staphylococcus aureus and Pseudomonas aeruginosa . PROCEDURES: Specimens were histologically scored for the amount of inflammation, edema, angiogenesis, fibrosis organization, and epithelialization...
March 2020: American Journal of Veterinary Research
Lisa M Freeman, Kathryn E Michel, Brian M Zanghi, Brittany M Vester Boler, Julien Fages
OBJECTIVE: To compare muscle condition scores (MCSs) and muscle ultrasonographic measurements in cats with and without muscle loss and to evaluate repeatability and reproducibility of MCS assessment. ANIMALS: 40 cats of various ages, body condition scores (BCSs), and MCSs. PROCEDURES: A prospective cross-sectional study was conducted. Body weight, BCS, MCS, epaxial muscle height (EMH), vertebral epaxial muscle score (VEMS), and forelimb epaxial muscle score (FLEMS) were assessed in each cat...
March 2020: American Journal of Veterinary Research
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"