American Journal of Veterinary Research | Page 3

Hirofumi Tanoue, Rika Uchiyama, Hideyuki Fukuda, Tom Ichinohe, Nobuo Kanno, Shuji Suzuki, Yasuji Harada, Yasushi Hara
OBJECTIVE: To investigate the effects of intervertebral distraction screw (IDS) fixation of the lumbosacral joint (LSJ) on the intervertebral foraminal area (IFA) and intervertebral stabilization of the LSJ and adjacent lumbar segments in dogs. ANIMALS: 7 healthy Beagles. PROCEDURES: Dorsal laminectomy was performed at the LSJ in each dog to expose the intervertebral disk. The IDS was then inserted into the L7-S1 disk. Computed tomography was performed before and after laminectomy and after IDS insertion (intact, laminectomy, and IDS conditions, respectively) to measure the intervertebral range of motion (ROM) and intervertebral distance (ID) at L7-S1, L6-7, and L5-6 with the LSJ in a flexed and extended position...
April 2020: American Journal of Veterinary Research
Kate P Sharon, Caryn M Thompson, B Duncan X Lascelles, Rudolph S Parrish
OBJECTIVE: To develop methods to identify and characterize activity monitor (AM) data signatures for jumps performed by cats. ANIMALS: 13 healthy, client-owned cats without evidence of osteoarthritis or degenerative joint disease. PROCEDURES: Each cat was fitted with the same AM, individually placed in an observation room, then simultaneously recorded by 3 video cameras during the observation period (5 to 8 hours). Each cat was encouraged to jump up (JU), jump down (JD), and jump across (JA) during the observation period...
April 2020: American Journal of Veterinary Research
Ian C Simcock, J Ciaran Hutchinson, Susan C Shelmerdine, Jose Novos Matos, Neil J Sebire, Virginia Luis Fuentes, Owen J Arthurs
OBJECTIVE: To determine optimal sample preparation conditions with potassium triiodide (I2 KI) and optimal imaging settings for microfocus CT (micro-CT) of excised cat hearts. SAMPLE: 7 excised hearts (weight range, 10 to 17.6 g) obtained from healthy adult cats after euthanasia by IV injection of pentobarbital sodium. PROCEDURES: Following excision, the hearts were preserved in 10% formaldehyde solution. Six hearts were immersed in 1.25% I2 KI solution (n = 3) or 2...
April 2020: American Journal of Veterinary Research
Rebecca L Tinklenberg, Shane D Murphy, Jonathan P Mochel, Yeon-Jung Seo, Alyssa L Mahaffey, Yuqi Yan, Jessica L Ward
OBJECTIVE: To determine whether a dose-response relationship exists between short-term oral prednisone administration and common clinicopathologic variables, cardiovascular biomarkers, and systolic arterial blood pressure (SAP) in healthy dogs. ANIMALS: 8 healthy Beagles. PROCEDURES: Dogs underwent five 5-day experiments (no prednisone treatment [control condition] and prednisone administration at 0.5, 1, 2, and 4 mg/kg, PO, q 24 h), with a 9-day washout period between protocols...
April 2020: American Journal of Veterinary Research
Yasutomo Hori, Yohei Yamashita, Keiichiro Sakakibara, Tadashi Sano, Ai Hori
OBJECTIVE: To investigate whether lung ultrasonography (LUS) performed around the heart, where the lungs are in contact with the pericardium (ie, pericardial LUS), could be used for the diagnosis of cardiogenic pulmonary edema (CPE) in dogs with degenerative mitral valve disease (DMVD). ANIMALS: 15 control dogs with healthy hearts and 26 dogs with DMVD. PROCEDURES: In a prospective multicenter study design, dogs with DMVD were assigned to 2 groups: those with CPE (n = 11) and those without CPE (15)...
March 2020: American Journal of Veterinary Research
Michael J Yaeger, Zuowei Wu, Paul J Plummer, Orhan Sahin, Melda Meral Ocal, Ashenafi F Beyi, Changyun Xu, Qijing Zhang, Ronald W Griffith
OBJECTIVE: To evaluate the efficacy of tulathromycin for prevention of abortion in pregnant ewes when administered within 24 hours after experimental inoculation with Campylobacter jejuni. ANIMALS: 20 pregnant ewes between 72 and 92 days of gestation. PROCEDURES: All ewes were inoculated with a field strain of C jejuni (8.5 × 108 to 10.6 × 108 CFUs, IV). Eighteen hours later, ewes received either tulathromycin (1.1 mL/45 kg [2.4 mg/kg], SC; n = 10) or sterile saline (0...
March 2020: American Journal of Veterinary Research
Samuel Frei, David Sanchez-Migallon Guzman, Philip H Kass, Michelle A Giuffrida, Philipp D Mayhew
OBJECTIVE: To compare a ventral and a left lateral endoscopic approach to coelioscopy in bearded dragons ( Pogona vitticeps ). ANIMALS: 18 adult bearded dragons. PROCEDURES: In a randomized crossover design involving 2 surgical approaches, anesthetized bearded dragons first underwent coelioscopy with a ventral approach (left lateral of midline next to the umbilicus; animal positioned in dorsal recumbency) or left lateral approach (intercostal; animal positioned in right lateral recumbency) and then with the alternate approach...
March 2020: American Journal of Veterinary Research
(no author information available yet)
No abstract text is available yet for this article.
March 2020: American Journal of Veterinary Research
Alyssa B Word, P Rand Broadway, Nicole C Burdick Sanchez, John P Hutcheson, Guy B Ellis, Ben P Holland, Michael A Ballou, Jeffery A Carroll
OBJECTIVE: To quantify acute immunologic and metabolic responses of beef heifers following topical administration of transdermal flunixin meglumine (TDFM) at various times relative to bovine herpesvirus 1 (BHV1) and Mannheimia haemolytica challenges. ANIMALS: 32 beef heifers (mean body weight, 170 kg). PROCEDURES: Heifers were assigned to 1 of 4 groups. Heifers in the control group did not receive TDFM, whereas 1 dose of TDFM (3.3 mg/kg) was topically applied to heifers of groups A, V, and B at -144, -72, and 0 hours...
March 2020: American Journal of Veterinary Research
Timothy L Foutz, Steven C Budsberg
OBJECTIVE: To develop a 3-D kinematic model to measure truncal motion in dogs and assess changes in truncal motion in dogs when wearing each of 2 service vests. ANIMALS: 5 adult mixed-breed dogs. PROCEDURES: 27 reflective markers were placed on the pelvis, trunk, and scapula of each dog. Six infrared cameras were placed around a treadmill to track the location of the markers within a calibrated space. Dogs were recorded during walking and trotting on the treadmill...
March 2020: American Journal of Veterinary Research
Elin J Rgensen, Freja B Hjerpe, Hans P Hougen, Thomas Bjarnsholt, Lise C Berg, Stine Jacobsen
OBJECTIVE: To evaluate histologic changes and gene expression patterns in body and limb wounds in horses in response to bacterial inoculation. SAMPLE: Wound biopsy specimens from 6 horses collected on days 7, 14, 21, and 27 after excisional wounds (20 wounds/horse) were created over the metacarpal and metatarsal region and lateral thoracic region (body) and then inoculated or not inoculated on day 4 with Staphylococcus aureus and Pseudomonas aeruginosa . PROCEDURES: Specimens were histologically scored for the amount of inflammation, edema, angiogenesis, fibrosis organization, and epithelialization...
March 2020: American Journal of Veterinary Research
Lisa M Freeman, Kathryn E Michel, Brian M Zanghi, Brittany M Vester Boler, Julien Fages
OBJECTIVE: To compare muscle condition scores (MCSs) and muscle ultrasonographic measurements in cats with and without muscle loss and to evaluate repeatability and reproducibility of MCS assessment. ANIMALS: 40 cats of various ages, body condition scores (BCSs), and MCSs. PROCEDURES: A prospective cross-sectional study was conducted. Body weight, BCS, MCS, epaxial muscle height (EMH), vertebral epaxial muscle score (VEMS), and forelimb epaxial muscle score (FLEMS) were assessed in each cat...
March 2020: American Journal of Veterinary Research
Francesca Del Baldo, Luca Magna, Francesco Dondi, Paolo Maramieri, Oana M Catrina, Sara Corradini, Guido Linari, Stefania Golinelli, Antonio M Tardo, Ugo Bonfanti, Federico Fracassi
OBJECTIVE: To evaluate the performance of 2 assays for measurement of serum fructosamine (SF) and glycated hemoglobin (HbA1c) values in dogs and to compare the usefulness of the 2 glycated proteins for assessment of glycemic control in dogs with diabetes mellitus (DM). SAMPLE: Blood samples from 40 healthy dogs, 13 diabetic dogs, and 23 anemic normoglycemic nondiabetic dogs and results of 200 assessments of glycemic control in 46 diabetic dogs. PROCEDURES: Colorimetric and immunoturbidimetric methods were used for measurement of SF and HbA1c values, respectively...
March 2020: American Journal of Veterinary Research
Daniel J Duffy, Yi-Jen Chang, Julie A Balko, George E Moore
OBJECTIVE: To evaluate the effect of presurgical storage conditions on leakage pressures of enterotomy sites closed with unidirectional barbed suture material in fresh, chilled, and frozen-thawed cadaveric canine jejunal specimens. SAMPLE: 36 grossly normal jejunal segments obtained from 4 dog cadavers. PROCEDURES: 9 jejunal segments were harvested immediately from each euthanized dog and randomly assigned to be tested within 4 hours after collection (fresh segments), stored at 4°C for 24 hours before testing (chilled segments), or stored at -20°C for 7 days and thawed at 21°C for 6 hours before testing (frozen-thawed segments)...
March 2020: American Journal of Veterinary Research
(no author information available yet)
No abstract text is available yet for this article.
March 2020: American Journal of Veterinary Research
Rachel A Allbaugh, Rita F Wehrman, Lionel Sebbag
OBJECTIVE: To compare the efficacy of 0.05% difluprednate ophthalmic emulsion and 1% prednisolone acetate ophthalmic suspension for controlling aqueocentesis-induced breakdown of the blood-aqueous barrier in healthy dogs. ANIMALS: 34 healthy dogs. PROCEDURES: Dogs were allocated to 5 groups (6 to 8 dogs/group) to receive 0.05% difluprednate, 1% prednisolone acetate, or saline (0.9% NaCl) solution (control treatment) in both eyes 2 or 4 times daily...
March 2020: American Journal of Veterinary Research
Bianca N Lourenço, Amanda E Coleman, Chad W Schmiedt, Cathy A Brown, Daniel R Rissi, James B Stanton, Steeve Giguère, Roy D Berghaus, Scott A Brown, Jaime L Tarigo
OBJECTIVE: To characterize transcription of profibrotic mediators in renal tissues of cats with ischemia-induced chronic kidney disease (CKD). SAMPLE: Banked renal tissues from 6 cats with experimentally induced CKD (RI group) and 8 healthy control cats. PROCEDURES: For cats of the RI group, both kidneys were harvested 6 months after ischemia was induced for 90 minutes in 1 kidney. For control cats, the right kidney was evaluated. All kidney specimens were histologically examined for fibrosis, inflammation, and tubular atrophy...
February 2020: American Journal of Veterinary Research
Laurel E Redding, Sondra Lavigne, Helen W Aceto, Rose D Nolen-Walston
OBJECTIVE: To characterize antimicrobial prescribing patterns of clinicians and clinical services at a large animal veterinary teaching hospital and identify factors associated with antimicrobial prescribing. ANIMALS: All large animals (ie, equids, bovids, sheep, goats, camelids, swine, and cervids) evaluated at the New Bolton Center hospital at the University of Pennsylvania from 2013 through 2018. PROCEDURES: In a cross-sectional study design, data on antimicrobial use by clinicians and clinical services were collected from administrative and billing records...
February 2020: American Journal of Veterinary Research
Valentina Vitale, Judit Viu, Lara Armengou, José Ríos, Eduard Jose-Cunilleras
OBJECTIVE: To evaluate the prognostic value of measuring heart rate variability (HRV) in horses with colic at the time of admission to a referral hospital. ANIMALS: 51 horses > 1 year of age with colic (41 that survived [survivors] and 10 that died or were euthanized [nonsurvivors]). PROCEDURES: HRV was recorded within 1 hour after admission by use of heart rate sensors with horses restrained in stocks. A 5-minute recording period was analyzed to obtain HRV measurements (eg, SD of R-R intervals [SDRR], root mean square of successive differences between R-R intervals [RMSSD], and geometric SDs determined from Poincaré plots [SD1 and SD2])...
February 2020: American Journal of Veterinary Research
(no author information available yet)
No abstract text is available yet for this article.
February 2020: American Journal of Veterinary Research
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