Use the journals feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Sunil Sethi, Shelly Sharma, Ashutosh N Aggarwal, Sunil Kumar Dhatwalia, Rajesh Rana, Rakesh Yadav
PURPOSE: To assess the Xpert MTB/XDR assay's efficiency in promptly detecting resistance to isoniazid, fluoroquinolones, ethionamide, and second-line injectable drugs among tuberculosis (TB) patients. METHODS: From August 2020 to July 2021, TB suspected patient samples were enrolled at a tertiary care center for our study. We conducted mycobacterial culture, phenotypic DST using proportion method in liquid culture at WHO-recommended concentrations, and the line probe assay (LPA)...
May 6, 2024: Infection
#2
JOURNAL ARTICLE
Paul Jonathan Roch, Carolin Ecker, Katharina Jäckle, Marc-Pascal Meier, Maximilian Reinhold, Friederike Sophie Klockner, Wolfgang Lehmann, Lukas Weiser
PURPOSE: Early diagnosis of surgical site infections (SSIs) could prevent surgical revision. Inflammatory markers (IMs), such as procalcitonin (PCT), interleukin-6 (IL-6), and tumor necrosis factor α (TNF-α), seem more accurate in diagnosing SSI than C-reactive protein (CRP) and white blood cell (WBC) count. The aim was to compare the predictive values of CRP, WBC count, PCT, IL-6, and TNF-α in SSI detection. METHODS: A total of 130 patients undergoing dorsal spondylodesis from 2019 to 2024 were enrolled in a prospective diagnostic study at a maximum care spine center...
May 6, 2024: Infection
#3
JOURNAL ARTICLE
Gamalat A Elgedawy, Naglaa S Elabd, Radwa H Salem, Samah M Awad, Amany A Amer, Mohammad M Torayah, Amal A El-Koa, Mai Abozeid, Belal A Montaser, Hind S Aboshabaan, Mervat Abdelkreem, Marwa L Helal
BACKGROUND AND AIM: A wide range of clinical manifestations and outcomes, including liver injury, have been reported in COVID-19 patients. We investigated the association of three substantial gene polymorphisms (FURIN, IFNL4, and TLR2) with COVID-19 disease susceptibility and severity to help predict prognosis. METHODS: 150 adult COVID-19-assured cases were categorized as follows: 78 patients with a non-severe presentation, 39 patients with severe disease, and 33 critically ill patients...
May 4, 2024: Infection
#4
JOURNAL ARTICLE
Elena Salamanca-Rivera, Zaira R Palacios-Baena, Javier E Cañada, Zaira Moure, María Pérez-Vázquez, Jorge Calvo-Montes, Luis Martínez-Martínez, Rafael Cantón, Guillermo Ruiz Carrascoso, Cristina Pitart, Ferran Navarro, Germán Bou, Xavier Mulet, Juan José González-López, Fran Sivianes, Mercedes Delgado-Valverde, Álvaro Pascual, Jesús Oteo-Iglesias, Jesús Rodríguez-Baño
BACKGROUND: Community-acquired (CA) and healthcare-associated (HCA) infections caused by carbapenemase-producing Enterobacterales (CPE) are not well characterized. The objective was to provide detailed information about the clinical and molecular epidemiological features of nosocomial, HCA and CA infections caused by carbapenemase-producing Klebsiella pneumoniae (CP-Kp) and Escherichia coli (CP-Ec). METHODS: A prospective cohort study was performed in 59 Spanish hospitals from February to March 2019, including the first 10 consecutive patients from whom CP-Kp or CP-Ec were isolated...
May 4, 2024: Infection
#5
JOURNAL ARTICLE
Inmaculada López Montesinos, Aina Carot-Coll, Maria Milagro Montero, Luisa Sorli Redó, Ana Siverio-Parès, Sandra Esteban-Cucó, Xavier Durán, Silvia Gomez-Zorrilla, Juan Pablo Horcajada
PURPOSE: The aim was to analyse the clinical and economic impact of carbapenemase-producing Enterobacterales (CPE) infections. METHODS: Case-control study. Adult patients with CPE infections were considered cases, while those with non-CPE infections were controls. Matching criteria were age (± 5 years), sex, source of infection and microorganism (ratio 1:2). Primary outcome was 30-day mortality. Secondary outcomes were 90-day mortality, clinical failure, hospitalisation costs and resource consumption...
May 3, 2024: Infection
#6
JOURNAL ARTICLE
Melania Degli Antoni, Giovanni Maifredi, Samuele Storti, Giorgio Tiecco, Marco Di Gregorio, Benedetta Rossi, Cinzia Gasparotti, Emanuele Focà, Francesco Castelli, Eugenia Quiros-Roldan
BACKGROUND: Our Hospital in Northern Italy assists 3817 people living with HIV (PLWH) and has faced the impact of COVID-19. Little is known about the impact of HIV infection on the risk of post-COVID-19 conditions (PCCs) onset. We aim to assess the incidence of PCC in PLWH and the factors associated with its occurrence. METHODS: We performed a retrospective, observational study including all PLWH > 18 years registered in the Brescia Health Protection Agency database, assessing SARS-CoV-2 burden, vaccination status, socio-demographic, and viro-immunological parameters from February 2020 until May 2022...
May 3, 2024: Infection
#7
JOURNAL ARTICLE
Daniele Pastori, Danilo Menichelli, Giulio Francesco Romiti, Angela Pia Speziale, Pasquale Pignatelli, Stefania Basili, Francesco Violi, Roberto Cangemi
PURPOSE: Patients hospitalized for community-acquired pneumonia (CAP) may have a higher risk of new-onset atrial fibrillation (NOAF). The C2 HEST score was developed to evaluate the NOAF risk in the general population. Data on the value of the C2 HEST score in acute patients admitted with CAP are lacking. We want to establish the predictive value of C2 HEST score for NOAF in patients with CAP. METHODS: Patients with CAP enrolled in the SIXTUS cohort were enrolled...
May 3, 2024: Infection
#8
JOURNAL ARTICLE
Sina M Hopff, Katharina S Appel, Olga Miljukov, Johannes Schneider, Marylyn M Addo, Robert Bals, Sven Bercker, Sabine Blaschke, Isabel Bröhl, Nikolaus Büchner, Hiwa Dashti, Johanna Erber, Anette Friedrichs, Ramsia Geisler, Siri Göpel, Marina Hagen, Frank Hanses, Björn-Erik Ole Jensen, Maria Keul, Adalbert Krawczyk, Bettina Lorenz-Depiereux, Patrick Meybohm, Milena Milovanovic, Lazar Mitrov, Carolin Nürnberger, Wilfried Obst, Christoph Römmele, Christian Schäfer, Christian Scheer, Margarete Scherer, Julia Schmidt, Kristina Seibel, Shimita Sikdar, Johannes Josef Tebbe, Phil-Robin Tepasse, Philipp Thelen, Maria J G T Vehreschild, Christina Weismantel, J Janne Vehreschild
PURPOSE: The influence of new SARS-CoV-2 variants on the post-COVID-19 condition (PCC) remains unanswered. Therefore, we examined the prevalence and predictors of PCC-related symptoms in patients infected with the SARS-CoV-2 variants delta or omicron. METHODS: We compared prevalences and risk factors of acute and PCC-related symptoms three months after primary infection (3MFU) between delta- and omicron-infected patients from the Cross-Sectoral Platform of the German National Pandemic Cohort Network...
May 3, 2024: Infection
#9
LETTER
Jörg C Prinz, Lars E French
No abstract text is available yet for this article.
May 2, 2024: Infection
#10
JOURNAL ARTICLE
Cristina Kirkegaard, Carlos Javier Parramón-Teixidó, Clara Morales-Comas, Susana Clemente Bautista, Joaquín Rivero Deniz, Nuria Fernández-Hidalgo
OBJECTIVES: Mastitis is mainly caused by Gram-positive bacteria and usually involves treatment with beta-lactam antibiotics and clindamycin. Oxazolidinones show good results in the treatment of skin and soft tissue infections (SSTIs) due to its pharmacokinetic characteristics. We aimed to describe clinical characteristics and outcomes of patients who received oxazolidinones for the treatment of SSTIs of the mammary tissue. METHODS: Retrospective single-centre study of patients with a diagnosis of breast infection who received treatment with oxazolidinones as initial or salvage therapy between September 2016 and November 2022...
May 1, 2024: Infection
#11
JOURNAL ARTICLE
Daniel Hornuss, Siri Göpel, Sarah V Walker, David Tobys, Georg Häcker, Harald Seifert, Paul G Higgins, Kyriaki Xanthopoulou, Beryl Primrose Gladstone, Chiara Cattaneo, Alexander Mischnik, Anna M Rohde, Can Imirzalioglu, Janina Trauth, Moritz Fritzenwanker, Jane Falgenhauer, Petra Gastmeier, Michael Behnke, Evelyn Kramme, Nadja Käding, Jan Rupp, Silke Peter, Kristina Schmauder, Simone Eisenbeis, Winfried V Kern, Evelina Tacconelli, Siegbert Rieg
PURPOSE: To analyse recent epidemiological trends of bloodstream infections (BSI) caused by Enterococcus spp. In adult patients admitted to tertiary care centres in Germany. METHODS: Epidemiological data from the multicentre R-NET study was analysed. Patients presenting with E. faecium or E. faecalis in blood cultures in six German tertiary care university hospitals between October 2016 and June 2020 were prospectively evaluated. In vancomycin-resistant enterococci (VRE), the presence of vanA/vanB was confirmed via molecular methods...
April 30, 2024: Infection
#12
Dima Hattab, Mumen F A Amer, Zina M Al-Alami, Athirah Bakhtiar
No abstract text is available yet for this article.
April 29, 2024: Infection
#13
JOURNAL ARTICLE
Kristin Vardheim Liyanarachi, Randi Marie Mohus, Tormod Rogne, Lise Tuset Gustad, Bjørn Olav Åsvold, Solfrid Romundstad, Erik Solligård, Stein Hallan, Jan Kristian Damås
PURPOSE: Bloodstream infections (BSI) and sepsis are important causes of hospitalization, loss of health, and death globally. Targetable risk factors need to be identified to improve prevention and treatment. In this study, we aimed to evaluate the association of chronic kidney disease (CKD) and risk of and mortality from BSI and sepsis in the general population during a 22-year period. METHODS: We conducted a prospective cohort study among participants in the population-based Norwegian HUNT Study, where 68,438 participated...
April 29, 2024: Infection
#14
JOURNAL ARTICLE
Le Li, Likun Zhou, Xi Peng, Zhuxin Zhang, Zhenhao Zhang, Yulong Xiong, Zhao Hu, Yan Yao
BACKGROUND: The stress hyperglycemia ratio (SHR), adjusted for average glycemic status, is suggested for assessing actual blood glucose levels. Its link with adverse outcomes is known in certain populations, yet its impact on sepsis patients' prognosis is unclear. This study explores the association between SHR and mortality in sepsis. METHODS: We included 13,199 sepsis patients in this study and categorized SHR into distinct groups. Additionally, we utilized restricted cubic spline analysis to evaluate the correlation between SHR as a continuous variable and mortality...
April 28, 2024: Infection
#15
JOURNAL ARTICLE
Ambre Sauvage, Emeline Laurent, Christophe Gaborit, Antoine Guillon, Leslie Grammatico-Guillon
BACKGROUND: Herpes simplex encephalitis (HSE) is a disease with unfavorable vital and functional prognoses. There are no recent epidemiological data on HSE at a national level using real-life databases, especially in France. This study aimed to report the incidence, the clinical characteristics and outcomes of the patients with HSE. METHODS: We conducted a comprehensive retrospective cohort study on all patients hospitalized for HSE in France between 2015 and 2022 using national hospital discharge databases...
April 28, 2024: Infection
#16
JOURNAL ARTICLE
Susanne Dyckhoff-Shen, Hans-Walter Pfister, Uwe Koedel, Matthias Klein
BACKGROUND: Meningococcal meningitis is still a severe disease causing high mortality and morbidity rates. Early diagnosis is crucial to ensure prompt antibiotic therapy. However, identification of the pathogen can be challenging. CASE PRESENTATION: A 32-year-old male patient with systemic lupus erythematosus (SLE) presented to the emergency room with fever, nausea, vomiting, headache and lower back pain as well as multiple petechial bleedings. On suspicion of meningococcal infection, the emergency doctor had already administered one dose of ceftriaxone before arrival to the clinic...
April 27, 2024: Infection
#17
JOURNAL ARTICLE
Peter Laursen Graversen, Lauge Østergaard, Morten Holdgaard Smerup, Jarl Emanuel Strange, Katra Hadji-Turdeghal, Marianne Voldstedlund, Lars Køber, Emil Fosbøl
PURPOSE: Surgery is required in 20-50% of patients with infective endocarditis (IE). Frailty increases surgical risk; however, the prognostic implications of frailty in patients undergoing IE-related surgery remain poorly understood. We aimed to assess the association between frailty and all-cause mortality or rehospitalization after discharge (≥ 14 days). METHODS: We identified all IE patients who underwent surgery during admission (2010-2020) in Denmark...
April 27, 2024: Infection
#18
Lisanne Boekhoud, Helena M E A Schaap, Rick L Huizinga, Tycho J Olgers, Jan C Ter Maaten, Douwe F Postma, Hjalmar R Bouma
No abstract text is available yet for this article.
April 26, 2024: Infection
#19
JOURNAL ARTICLE
Rafael Fayos-Gregori, Gonzalo Alonso-Fernández, Miguel Mansilla-Polo
This case report highlights a case of a 65-year-old woman who presented to our clinic with suspicion of refractory scabies. She had undergone multiple treatments without improvement. However, the clinical condition was not scabies but rather Gianotti-Crosti Syndrome (GCS), leading to rapid clinical improvement and avoiding the need for further unnecessary tests and treatments. GCS is a postviral exanthem characterized by symmetrical, red papules on the extremities and buttocks, typically occurring in children but can also affect adults...
April 26, 2024: Infection
#20
JOURNAL ARTICLE
Suzan Şahin, Ebru Fidan, Serap Demir Tekol, Bülent Kaya
Nocardia is a genus of aerobic, Gram-positive bacteria known for their filamentous and branching morphology. N. brasiliensis is the most common species causing cutaneous nocardiosis. We present a 67-year-old woman who developed abscesseson the back of her right ankle after walking barefoot on soil. Cultures from the cutaneous lesions grew N. brasiliensis. Antibiotic therapy with trimethoprim-sulfamethoxazole given for a month provided near-complete resolution of her lesions.
April 26, 2024: Infection
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
