Fan Zhang, Yu Yan, Jie-Kun Xu, Lin-Mei Zhang, Li Li, Xin Chen, Dong-Xu Li, Ying Peng, Hua Yang, Ling-Zhi Li, Jun He, Jiang Zheng, Wei-Ku Zhang
Fructus Corni (F. Corni) is the dried mature pulp of Cornus officinalis Sieb. et Zucc.(Cornaceae), which is rich in iridoids. In this study, a simple, sensitive and rapid UPLC-MS/MS method was developed for the simultaneous determination of 13 iridoid glycosides of F. Corni from different areas. Specifically, we included five new compounds (cornusdiridoid C, cornusdiridoid E, cornusdiridoid F, 3'',5''-dehydroxycornuside and 2'-O-p-coumaroyl-kingiside) and isomers (2'-O-p-E-coumaroylloganin and 2'-O-p-Z-coumaroylloganin) for the first time in the quality markers of F...
October 23, 2023: Journal of Chromatographic Science